Results 71 to 80 of about 4,757 (93)

Curated CYP450 Interaction Dataset: Covering the Majority of Phase I Drug Metabolism. [PDF]

Sci Data
Ni YH, Su YW, Yang SC, Hong JC, Du PA, Hsu YT, Kuo TC, Tseng YJ.   +7 more
europepmc   +1 more source

Distinct Interactions of Cannabinol and Its Cytochrome P450-Generated Metabolites with Receptors and Sensory Neurons. [PDF]

J Med Chem
Kundu D, Franchini L, Hasdemir HS, Lloyd E, Maturano J, Rabl K, Denissiouk AN, Schumacher M, Sarlah D, Hellman J, Tajkhorshid E, Orlandi C, Das A.   +12 more
europepmc   +1 more source

Metabolism of Cannabidiol in Respiratory-Associated Cells and HepG2-Derived Cells and Molecular Docking of Cannabidiol and Its Metabolites with CYP Enzymes and Cannabinoid Receptors. [PDF]

Int J Mol Sci
Tongkanarak K, Paul PK, Bintang MAKM, Suedee R, Sawatdee S, Srichana T.   +5 more
europepmc   +1 more source

Subgroup analysis of genotype guided vs traditional warfarin dosing in Asian patients from an open label randomized trial. [PDF]

Sci Rep
Wong HJ, Teo YN, Teo YH, Syn NL, Wong AL, Teoh HL, Seet RCS, Lee SC, Goh BC, Sia CH.   +9 more
europepmc   +1 more source

Role Assessment of Water-Soluble Pharmaceutical Form of Phosphatidylcholine on the Catalytic Activity of Cytochrome P450 2C9 and 2D6. [PDF]

Int J Mol Sci
Koroleva PI, Bulko TV, Kuzikov AV, Gilep AA, Romashova YA, Tichonova EG, Kostrukova LV, Archakov AI, Shumyantseva VV.   +8 more
europepmc   +1 more source

Physiologically Based Pharmacokinetic Modeling to Predict Drug-Drug Interactions of Soticlestat as a Victim of CYP Induction and Inhibition, and as a Perpetrator of CYP and P-Glycoprotein Inhibition. [PDF]

Clin Pharmacol Drug Dev
Jia H, Ballard TE, Zhang L, Cohen L, Bergagnini-Kolev MC, Templeton IE, Jones HM, Yin W.   +7 more
europepmc   +1 more source

Towards the Use of Metabolic Volatiles in Breath for Determining Drug Response: Gstachamine as an Unlabeled Substrate to Measure CYP3A4 Activity. [PDF]

ChemMedChem
Stock V, Hofer R, Liedl KR, Troppmair J, Langer T, Gstach H, Dank C, Kammerer S, Ruzsanyi V.   +8 more
europepmc   +1 more source

Building Sub-Saharan African PBPK Populations Reveals Critical Data Gaps: A Case Study on Aflatoxin B1. [PDF]

Toxins (Basel)
Lootens O, De Boevre M, De Saeger S, Van Bocxlaer J, Vermeulen A.   +4 more
europepmc   +1 more source

Epigenetics in pharmacogenes encoding metabolizing enzymes of second-generation antipsychotics used in schizophrenia and its clinical implications. [PDF]

Front Pharmacol
Alvarado AT, Zavaleta AI, Li-Amenero C, Bendezú MR, Garcia JA, Chávez H, Palomino-Jhong JJ, Surco-Laos F, Laos-Anchante D, Melgar-Merino EJ, Bolarte-Arteaga M, Tasayco-Yataco N, Pariona-Llanos R.   +12 more
europepmc   +1 more source