Results 71 to 80 of about 9,195 (133)

Effect of ritonavir on the pharmacokinetics of the benzimidazoles albendazole and mebendazole: an interaction study in healthy volunteers [PDF]

, 2018
Background: Benzimidazoles are often used concomitantly with protease inhibitors in patients with helminthic disease and HIV infection. Low bioavailability and extensive first-pass metabolism make benzimidazoles prone to pharmacokinetic drug interactions.
Corti, Natascia, Heck, Antje, Jetter, Alexander, Pauli-Magnus, Christiane, Rentsch, Katharina, Stieger, Bruno, Zingg, Walter   +6 more
core  

Publication Only

HemaSphere, Volume 9, Issue S1, June 2025.
wiley   +1 more source

Biology of PXR [PDF]

, 2014
Hormonal homeostasis is essential for a variety of physiological and pathological processes. Elimination and detoxification of xenobiotics, such as drugs introduced into the human body, could disrupt the balance of hormones due to the induction of drug ...
Dai, Shu, Guo, Yan, Wang, Jing, Xie, Wen, Zhai, Yonggong   +4 more
core  

Medical Marijuana-Induced Tacrolimus Toxicity. [PDF]

, 2019
As both recreational and therapeutic marijuana use increases in the US, more attention is being paid to its direct medical and psychoactive effects. One crucial dimension is the potential for marijuana or marijuana-derived therapies to interact with ...
Chism, Keira, Moadel, Daniel
core   +1 more source

Assessment of the Intestinal CYP3A Contribution to Drug Interactions with Extended-Release Tacrolimus (LCPT) Using Grapefruit Juice. [PDF]

Clin Pharmacol Drug Dev
Alabi A, Kerr JS, Shah M, Khan A, Ma JD, Suhandynata RT, Momper JD, Tsunoda SM.   +7 more
europepmc   +1 more source

Physiologically Based Pharmacokinetic Modeling of Valemetostat to Inform Dose Recommendations When Coadministered With CYP3A/P-gp Modulators. [PDF]

Clin Transl Sci
Watanabe A, Okudaira N, Tachibana M, Kazui M, Kotsuma M, Shimizu T, Lau Y.   +6 more
europepmc   +1 more source

Effect of Valemetostat on the Pharmacokinetics of Midazolam and Digoxin: A Phase 1 Drug-Drug Interaction Study in Patients With Non-Hodgkin Lymphoma. [PDF]

Clin Transl Sci
Tachibana M, Horwitz S, Jacobsen E, Foss F, Allen P, Porcu P, Feldman T, Ruan J, Brammer JE, Wang J, Inaba S, Iko Y, Nakajima K, Kakurai Y, Kitami N, Chen Y, Lau Y.   +16 more
europepmc   +1 more source

Genotype-Specific Safety and Pharmacokinetics of Cannabidiol in Healthy Volunteers. [PDF]

Clin Transl Sci
Etkins J, So GC, Lu JBL, Koyama S, Gisch DL, Melo Ferreira R, Cheng YH, McClara K, Jun J, Miller M, Desta Z, Eadon MT.   +11 more
europepmc   +1 more source

Interactions between xenoestrogens and ketoconazole on hepatic CYP1A and CYP3A, in juvenile Atlantic cod () [PDF]

core   +1 more source

Application of Physiologically-Based Pharmacokinetic Modeling to Support Drug Labeling: Prediction of CYP3A4-Mediated Pirtobrutinib-Drug Interactions. [PDF]

CPT Pharmacometrics Syst Pharmacol
Tian DD, Hall SD, Chapman SC, Posada MM.
europepmc   +1 more source