Results 161 to 170 of about 104,306 (283)

Effects of Botrychium ternatum (Thunb) Sw. On Cytochrome P450 Activities in Rats. [PDF]

Pharmacol Res Perspect
Yao J, Hu L, Zhou Q, Al Mamun A, Wang S, Han A.   +5 more
europepmc   +1 more source

Comparative lipidomic and proteomic analysis reveals species‐specific differences in midgut composition and insecticide absorption between Apis mellifera and Bombus terrestris

Pest Management Science, Volume 82, Issue 2, Page 1540-1551, February 2026.
Lipidomic and proteomic analysis revealed large‐scale differences in the midgut composition of the honeybee Apis mellifera and the buff‐tailed bumblebee Bombus terrestris. These differences correlated to increased insecticide absorption in the bumblebee when using an ex vivo Ussing chamber and subsequently in vivo feeding assay (created in Biorender ...
Emmanouil Kokkas, Joseph Hawkins, Lauraine Swindale, Aniko Kende, John Sinclair, Jacob M Riveron, Helen Thompson, Adam Pym   +7 more
wiley   +1 more source

Inhibitory effects of Δ8-tetrahydrocannabinol on major hepatic cytochrome P450 enzymes and implications for drug disposition. [PDF]

Drug Metab Dispos
Zhao M, Coates S, Bardhi K, Lazarus P.
europepmc   +1 more source

[Effect of modifiers of the cytochrome P-450-dependent enzyme system of the liver on the metabolic pathways of diethylnitrosamine activation and inactivation].

, 1987
Shuliakovskaia Ts, Koen IaM, Rykova Va, Loknitskaia Nn, Fonshteĭn Lm   +4 more
openalex   +1 more source

Dicloxacillin and Flucloxacillin Inhibit Hepatic Uptake Transporters—In Vitro Investigations and Physiologically Based Pharmacokinetic Modeling

Clinical and Translational Science, Volume 19, Issue 2, February 2026.
ABSTRACT Dicloxacillin and flucloxacillin are β‐lactamase‐resistant penicillin antibiotics that have been in clinical use for over 50 years. While both antibiotics are known to induce cytochrome P450 enzymes, there is limited information available regarding their interactions with drug transporters.
Noora Sjöstedt, Ogochukwu U. Amaeze, Jeroen J. M. W. van den Heuvel, Tore B. Stage, Jan B. Koenderink, Nina Isoherranen, Heidi Kidron, Erkka Järvinen   +7 more
wiley   +1 more source

Assessing Cytochrome P450 Drug Interaction Risk for Dordaviprone Using Physiologically Based Pharmacokinetic Modeling. [PDF]

CPT Pharmacometrics Syst Pharmacol
Jaiswal S, Patel NK, Jones HM, McFeely S, Faison SL, Tippin T, Naderer O.   +6 more
europepmc   +1 more source

Genetic Diversity, Population Structure and Differentiation of Farmed and Wild African Catfish (Clarias gariepinus) in Nigeria

Evolutionary Applications, Volume 19, Issue 2, February 2026.
ABSTRACT The African catfish (Clarias gariepinus) is a commercially important species, for both fisheries and aquaculture, and is now the most commonly farmed fish in sub‐Saharan Africa. However, knowledge about the genetic diversity and population structure of natural and farmed populations, which is crucial for effective conservation and sustainable ...
Mark K. Sanda, Neil B. Metcalfe, Maria Capstick, Jenna Nichols, Barbara K. Mable   +4 more
wiley   +1 more source

Use of P450 Enzymes for Late-Stage Functionalization in Drug Discovery. [PDF]

J Med Chem
Poon V, Bailey C, Carvalho S, Patterson S, Fyfe JWB, Semenova O, Wrigley SK, Hopkins E, Manohar R, Drake C, Kokubun T, Boyle J, Kvaerno L, Lees K, Hoffmann KF, Forde-Thomas J, Wyllie S, Steele J, Gilbert IH, Tarver GJ.   +19 more
europepmc   +1 more source

Acute hepatitis and haemolysis associated with doxycycline and rifampin administration in two weanling foals

Equine Veterinary Education, Volume 38, Issue 2, Page e70-e77, February 2026.
Summary Two foals were being treated with a combination of oral doxycycline and rifampin for presumed Rhodococcus equi infections. After 3–4 weeks of antimicrobial administration, both foals presented with icterus and nonspecific clinical signs, including lethargy and inappetence.
A. Murdock, D. Wong, T. Hall, B. Sponseller, J. Howard, K. Frerichs, A. Bianco, R. Ruby   +7 more
wiley   +1 more source

Perioral dermatitis secondary to topical clascoterone 1. [PDF]

JAAD Case Rep
Noda M, Zureigat M.
europepmc   +1 more source