Results 51 to 60 of about 778,835 (257)

An Update: Enzymatic Synthesis for Industrial Applications

Angewandte Chemie International Edition, Accepted Article.
Supported by rapid technological advancements, biocatalytic applications have matured into a sustainable, scalable, and cost‐competitive alternatives to established chemical catalysis. This review presents the most recent examples of enzyme‐based solutions for the manufacturing of molecules with extended carbon‐carbon frameworks and multiple ...
Thomas Bayer, Shuke Wu, Radka Snajdrova, Kai Baldenius, Uwe Bornscheuer   +4 more
wiley   +1 more source

Modelling studies on a secondary metabolite from Saccharomyces cerevisiae. [PDF]

, 2018
Modelling studies were performed on a fermentation system using Saccharomyces cerevisiae NCYC 754. The production of fermentation product and cytochrome P-450 were studied under semi-anaerobic condition in batch cultures. The fermentation was carried out
Leung, Chun Sau.
core   +1 more source

Towards Scalable Electroenzymatic Hydrogen Production with [FeFe]‐Hydrogenase

ChemElectroChem, EarlyView.
The [FeFe]‐hydrogenase metalloenzyme is a promising biocatalyst for sustainable electrocatalytic hydrogen (H2) production, however important issues need to be addressed before this can happen. For future biotechnologies to be realized, the [FeFe]‐hydrogenase enzyme should be more oxygen resistant, be produced in viable quantities and ultimately ...
Sophie Webb, Ross D. Milton
wiley   +1 more source

Pacman percolation: a model for enzyme gel degradation [PDF]

Phys. Rev. Lett. 93, 228301 (2004), 2004
We study a model for the gel degradation by an enzyme, where the gel is schematized as a cubic lattice, and the enzyme as a random walker, that cuts the bonds over which it passes. The model undergoes a (reverse) percolation transition, which for low density of enzymes falls in a universality class different from random percolation.
arxiv   +1 more source

Caloric Restriction Affects Liver Microsomal Monooxygenases Differentially in Aging Male Rats [PDF]

, 2017
Caloric restriction (CR) extends life span and retards the onset of physiological changes and pathologies associated with aging, but the underlying mechanisms remain unresolved.
Marti, Ulrich, Schmucker, Douglas L., Snyder, David, Strobel, Henry, Wang, Rose K.   +4 more
core  

Characterization and Solubilization of Kaurenoic Acid Hydroxylase from Gibberella fujikuroi [PDF]

, 1993
A key step in gibberellin biosynthesis is the conversion of ent-kaurenoic acid to ent-7[alpha]-hydroxykaurenoic acid, mediated by the enzyme kaurenoic acid hydroxylase. A cell-free system obtained from Gibberella fujikuroi (Saw.) Wr.
C. A. West, D. A. Nakata, J. C. Jennings, R. C. Coolbaugh   +3 more
core   +2 more sources

Molecular Synchronization Waves in Arrays of Allosterically Regulated Enzymes [PDF]

Phys. Rev. Lett. 99, 048301 (2007), 2007
Spatiotemporal pattern formation in a product-activated enzymic reaction at high enzyme concentrations is investigated. Stochastic simulations show that catalytic turnover cycles of individual enzymes can become coherent and that complex wave patterns of molecular synchronization can develop. The analysis based on the mean-field approximation indicates
arxiv   +1 more source

Human P450 CYP17A1: Control of Substrate Preference by Asparagine 202 [PDF]

, 2018
CYP17A1 is a key steroidogenic enzyme known to conduct several distinct chemical transformations on multiple substrates. In its hydroxylase activity, this enzyme adds a hydroxyl group at the 17α position of both pregnenolone and progesterone at ...
Bangcharoenpaurpong O., James R. Kincaid, Mak P. J., Michael C. Gregory, Nakajin S., Piotr J. Mak, Shen A. L., Stephen G. Sligar, Yogan Khatri   +8 more
core   +2 more sources

Photoinduced Electron Transfer in Ruthenium‐Polypyridyl‐Modified Laccases: Probing Pathways From the Surface to the Metal Centers

Chemistry – A European Journal, EarlyView.
This study investigates photoinduced electron transfer (PIET) within a multicopper oxidase by grafting a ruthenium‐polypyridyl photosensitizer onto different positions on its surface. We uncover alternative ET pathways to the enzyme's copper centers, in which the trinuclear cluster is photoreduced directly without first passing through the Type 1 ...
Iago de Assis Modenez, Annamaria Quaranta, Elise Courvoisier‐Dezord, Yasmina Mekmouche, A. Jalila Simaan, Winfried Leibl, Thierry Tron   +6 more
wiley   +1 more source

Aryl Hydrocarbon Hydroxylase, Epoxide Hydrolase, and Benzo[a]pyrene Metabolism in Human Epidermis: Comparative Studies in Normal Subjects and Patients with Psoriasis [PDF]

, 1984
Prior studies have shown that human skin possesses a cytochrome P-450-dependent microsomal enzyme that is capable of metabolizing drugs and polycyclic aromatic hydrocarbon (PAH) carcinogens.
David R. Bickers, Hasan Mukhtar, Tapu Dutta-Choudhury, Cynthia L. Marcelo, John J. Voorhees, Blum, Hueper, Bickers, Miller, Heidelberger, Gelboin, Daudel, Levin, Koreeda, Alvares, Bickers, Oesch, Nebert, Nebert, Chapman, Shuster, Stern, Rawlins, Finnen, Voorhees, Nebert, Mukhtar, Lowry, Bickers, Bickers, Chapman, Chapman, Shuster, Pott, Blum, Henry, Harber, Goeckerman, Kellermann, Paigen, McLemore, Prasad, Fletcher, Paigen, Jett, Ruzicka, Karki   +46 more
core   +7 more sources