Results 31 to 40 of about 127,252 (263)
The study was performed to investigate the effects of the separate and combined action of omega-3 polyunsaturated fatty acids (ω-3 PUFAs) and vitamin D3 on the activity of the components of the oxygenase and reductase chains of the monooxygenase system ...
I. O. Shymanskyi+3 more
doaj +1 more source
Evolution favors protein mutational robustness in sufficiently large populations [PDF]
BACKGROUND: An important question is whether evolution favors properties such as mutational robustness or evolvability that do not directly benefit any individual, but can influence the course of future evolution. Functionally similar proteins can differ substantially in their robustness to mutations and capacity to evolve new functions, but it has ...
arxiv +1 more source
Neutral genetic drift can aid functional protein evolution [PDF]
BACKGROUND: Many of the mutations accumulated by naturally evolving proteins are neutral in the sense that they do not significantly alter a protein's ability to perform its primary biological function. However, new protein functions evolve when selection begins to favor other, "promiscuous" functions that are incidental to a protein's biological role.
arxiv +1 more source
Cytochrome P450, a family of monooxygenase enzymes, is organized as a catalytic metabolon, which requires enzymatic partners as well as environmental factors that tune its complex dynamic.
Carlo Barnaba+3 more
doaj +1 more source
Background: Procollagen type I amino-terminal propeptide (PINP) is often present during osteoblast development and could be a biomarker of early bone development. Osteoprotegerin (OPG) may protect tumor cells from apoptosis.
Yousif Pshtiwan A.+1 more
doaj +1 more source
The COS-7 (CV-1 in Origin with SV40 genes) cells are known as non-steroidogenic cells because they are derived from kidney cells and the kidney is defined as a non-steroidogenic organ.
Mitsuki Nozaki+9 more
doaj +1 more source
HETEROLOGOUS EXPRESSION OF RECOMBINANT MOUSE CYTOCHROME P450 2E1 IN ESCHERICHIA COLI
Aim. The cloning of the mouse cytochrome P450 2E1 cDNA and obtaining of expression of cloned cDNA in E. coli. Methods. Polymerase chain reaction, cloning techniques, electrophoresis, Western blot. Results.
В. Н. Заец+4 more
doaj +1 more source
Remediation of bentazone contaminated water by Trametes versicolor: characterization, identification of transformation products, and implementation in a trickle-bed reactor under non-sterile conditions [PDF]
Bentazone, an herbicide widely applied in rice and cereal crops, is widespread in the aquatic environment. This study evaluated the capacity of Trametes versicolor to remove bentazone from water. The fungus was able to completely remove bentazone after three days at Erlenmeyer-scale incubation.
arxiv +1 more source
Antioxidant Activities of Celery and Parsley Juices in Rats Treated with Doxorubicin
We have examined the influence of diluted pure celery and parsley leaf and root juices and their combinations with doxorubicin on the antioxidant status [as measured by the content of reduced glutathione (GSH) and ferric reducing antioxidant power (FRAP)]
Svetlana Trivic+4 more
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The interplay between tubulins and P450 cytochromes during Plasmodium berghei invasion of Anopheles gambiae midgut. [PDF]
BACKGROUND: Plasmodium infection increases the oxidative stress inside the mosquito, leading to a significant alteration on transcription of Anopheles gambiae detoxification genes.
Rute C Félix, Henrique Silveira
doaj +1 more source