Results 81 to 90 of about 127,252 (263)
Inhibition of Human Cytochrome P450 Metabolism by Blended Herbal Products and Vitamins
Journal of Pharmacy & Pharmaceutical Sciences, 2011 Purpose. The use of supplements as herbal and micronutrient natural health products with conventional health products has become increasingly popular.
Teresa W Tam +10 more
doaj +1 more source
Scientific Reports, 2022 Chimeric TK-NOG mice with a humanized liver (normal Hu-liver) are a unique animal model for predicting drug metabolism in humans. However, residual mouse hepatocytes occasionally prevent the precise evaluation of human drug metabolism.
Shotaro Uehara +14 more
doaj +1 more source
On the occurrence of cytochrome P450 in viruses [PDF]
Proceedings of the National Academy of Sciences, 2019 Genes encoding cytochrome P450 (CYP; P450) enzymes occur widely in the Archaea, Bacteria, and Eukarya, where they play important roles in metabolism of endogenous regulatory molecules and exogenous chemicals. We now report that genes for multiple and unique P450s occur commonly in giant viruses in the Mimiviridae ,
Lamb, David +9 more
openaire +6 more sources
Presence of cytochrome P450 in the Caribbean corals Siderastrea siderea and Montastraea faveolata
Ciencias Marinas, 2005 Cytochrome P450 was detected in the animal tissue of the scleractinian corals Siderastrea siderea and Montastraea faveolata collected from a reef site on the west coast of Venezuela.
E García, R Ramos, C Bastidas
doaj +1 more source
Prodrugs of the Archetypal Dynamin Inhibitor Bis‐T‐22
ChemMedChem, Volume 17, Issue 24, December 16, 2022., 2022 The Bis‐T series of compounds comprise some of the most potent inhibitors of dynamin GTPase activity yet reported, such as Bis‐T‐22 (2). The catechol moieties are believed to limit cell permeability, rendering these compounds largely inactive in cells.
Luke R. Odell +6 more
wiley +1 more source
Biological Research, 2003 Liver microsomal cytochrome P4502E1-dependent p-nitrophenol (PNP) hydroxylation and expression of cytochrome P4502E1 were studied in rats subjected to g-hexachlorocyclohexane (HCCH) or L-3,3,,5-triiodothyronine (T3) administration as a possible mechanism
VIRGINIA FERNÁNDEZ +8 more
doaj
Specific Heat upon Aqueous Unfolding of the Protein Interior: A Theoretical Approach [PDF]
, 2001 We study theoretically the thermodynamics, over a broad temperature range (5 C to 125 C), related to hydrated water upon protein unfolding. The hydration effect is modeled as interacting dipoles in an external field, mimicking the influence from the unfolded surfaces on the surrounding water compared to bulk water.
arxiv +1 more source
Intensive Production of Carboxylic Acids Using C. butyricum in a Membrane Bioreactor (MBR)
Fermentation, 2018 This work reports on the use of a bench-scale chemostat (CSTR) in continuous mode and of a pilot-scale membrane bioreactor (MBR) in fed-batch mode to intensively produce acetic and butyric acids using C. butyricum grown on synthetic media.
Husnul Azan Tajarudin +4 more
doaj +1 more source
Relationships among the nucleotide content of human genome sequence, gene structure, and gene expression features (PhD synopsis) [PDF]
arXiv, 2010 The Dissertation is focused on the studies of associations between functional elements in human genome and their nucleotide structure. The asymmetry in nucleotide content (skew, bias) was chosen as the main feature for nucleotide structure. A significant difference in nucleotide content asymmetry was found for human exons vs. introns.
arxiv
Cytochromes P450: a success story.
Genome biology, 2000 Cytochrome P450 proteins, named for the absorption band at 450 nm of their carbon-monoxide-bound form, are one of the largest superfamilies of enzyme proteins. The P450 genes (also called CYP) are found in the genomes of virtually all organisms, but their number has exploded in plants.
Werck-Reichhart,, Feyereisen, R.
openaire +6 more sources