Results 91 to 100 of about 56,650 (349)

Kidney Organoids in Drug Development: Integrating Technological Advances and Standardization for Effective Implementation

Advanced Healthcare Materials, EarlyView.
This review examines how emerging enabling technologies enhance the physiological relevance, scalability, and reproducibility of kidney organoids, while advanced analytical approaches support model validation and deepen mechanistic insight into nephrotoxicity.
Helen Kearney, Silvia M. Mihăilă, Lorenzo Moroni, Carlos Mota   +3 more
wiley   +1 more source

Some Properties of Plastidic Cytochrome b-563

Zeitschrift für Naturforschung C, 1977
Abstract Plastidic Cytochrome b-563 Cytochrome b-563 from spinach chloroplasts was isolated in a homogeneous and enzymatically active form. It has a low, but variable lipid content and a molecular weight of about 18,000 daltons.
H J, Lach, P, Böger
openaire   +2 more sources

Microbial electrocatalysis with Geobacter sulfurreducens biofilm on stainless steel cathodes [PDF]

, 2008
Stainless steel and graphite electrodes were individually addressed and polarized at−0.60V vs. Ag/AgCl in reactors filled with a growth medium that contained 25mM fumarate as the electron acceptor and no electron donor, in order to force the microbial ...
Afkar, Alain Bergel, Bergel, Bond, Claire Dumas, Gorby, Gregory, Gregory, He, Logan, Lopez-Lopez, Lovley, Lovley, Lovley, Methé, Myers, Park, Park, Reguera, Rhoads, Régine Basseguy, Seeliger   +21 more
core   +1 more source

Biocompatible Ink Optimization Enables Functional Volumetric Bioprinting With Xolography

Advanced Materials, EarlyView.
Xolography's reliance on weak‐base co‐initiators introduces unique biochemical constraints. By dissecting the effects of extracellular pH, osmolality, and lysosomotropic stress, this study defines the biochemical design space that enables fully biocompatible, cell‐laden volumetric printing. Abstract Xolography is a novel linear volumetric manufacturing
Erik Brauer, Aiste Balciunaite, Matthias R. Kollert, Julian Weihs, Raphael S. Knecht, Rose Behncke, Susanna Quach, Niklas Felix König, Asia Badolato, Stella Monestier, Simone Bersini, Matteo Moretti, Miriam Filippi, René Hägerling, Milad Rezvani, Stefan Hecht, Ansgar Petersen, Robert K. Katzschmann   +17 more
wiley   +1 more source

Mitochondria‐Targeted Nanomotor: H2S‐Driven Cascade Therapy for Hepatocellular Carcinoma

Advanced Materials, EarlyView.
A mitochondrial‐targeted nanomotor integrates photodynamic therapy, mild photothermal therapy, and enzyme dynamic therapy into a self‐amplifying cascade through H2S‐driven metabolic reprogramming. Abstract Despite advances in combination therapies for cancer treatment, most strategies rely on modular‐additive designs that lack dynamic molecular cues to
Chengcheng Li, Xiaodong Ma, Shiji Fang, Biao Chen, Xinru Wang, Lingyun He, Xin Yang, Yuanqiang Li, Jessica M. Rosenholm, Zhongwei Zhao, Jiansong Ji, Hongbo Zhang   +11 more
wiley   +1 more source

Leishmaniosis cutanea: manifestación clínica inusual

Revista Peruana de Medicina Experimental y Salud Pública
Las manifestaciones clínicas de la leishmaniosis son variables y están relacionadas con la especie infectante, su relación con el medioambiente y con la respuesta inmune del hospedero.
Aidé Sandoval-Juárez, Gloria Minaya-Gómez, Nyshon Rojas-Palomino, Eduardo Falconi, Omar Cáceres   +4 more
doaj  

Structural role of the tyrosine residues of cytochrome c [PDF]

, 1982
The tertiary structures of horse, tuna, Neurospora crassa, horse [Hse65,Leu67]- and horse [Hse65,Leu74]-cytochromes c were studied with high-resolution 1H n.m.r. spectroscopy.
Boon, Peter J., Brinkhof, Herman H. K., Eley, Crispin G. S., Moore, Geoffrey R., Neupert, Walter, Nivard, Rutger J. F., Tesser, Godefridus I., Williams, Robert J. P.   +7 more
core  

Mitochondria‐Specific Protein Delivery by Protease‐Triggered Release in Plants with Single‐Walled Carbon Nanotubes

Advanced Materials Technologies, EarlyView.
Polymer‐coated carbon nanotubes were engineered as protease‐responsive nanocarriers for protein delivery in intact plants. GFP cargo can be released by cytosolic phytaspase cleavage and subsequently targeted to mitochondria via an N‐terminal sequence, enabling controlled intracellular protein delivery without tissue damage and demonstrating stable ...
Simon Sau Yin Law, Takehiro Suzuki, Tsuyohiko Fujigaya, Keiji Numata   +3 more
wiley   +1 more source

Schisandrin B elicits the Keap1-Nrf2 defense system via carbene reactive metabolite which is less harmful to mice liver

Drug Design, Development and Therapy, 2018
Shan Feng,* Bingxun Qiu,* Li Zou, Ke Liu, Xiaoyu Xu, Huifeng Zhu College of Pharmaceutical Sciences and Chinese Medicine, Southwest University, Beibei, Chongqing 400715, China *These authors contributed equally to this work Background: Schisandrin B ...
Feng S, Qiu B, Zou L, Liu K, Xu X, Zhu H
doaj  

Proteins derived from green biomass: Alfalfa (Medicago sativa L.) and water lentil concentrate (Lemna minor L.) in the focus as stabilizers for emulsions

Food Hydrocolloids for Health
Green crop biomass is a sustainable protein source, which can support solving global food challenges as well as improving the bioeconomy for novel food utilization. Two green biomasses -alfalfa and water lentil- known for a high protein content and their
Maren Müller, Olaf Holderer, Kuno Schwärzer, Anika Wiese-Klinkenberg, Beate Förster, Stephan Förster, Joachim Kohlbrecher, Kathleen Wood, Baohu Wu, Stephan Hauschild, Henrich Frielinghaus, Theresia Heiden-Hecht   +11 more
doaj   +1 more source