Results 51 to 60 of about 18,948,758 (389)

The pio Operon Is Essential for Phototrophic Fe(II) Oxidation in Rhodopseudomonas palustris TIE-1 [PDF]

, 2006
Phototrophic Fe(II)-oxidizing bacteria couple the oxidation of ferrous iron [Fe(II)] to reductive CO2 fixation by using light energy, but until recently, little has been understood about the molecular basis for this process. Here we report the discovery,
Jiao, Yongqin, Newman, Dianne K.
core   +4 more sources

Apocytochrome c [PDF]

, 1990
The cytochrome c import pathway differs markedly from the general route taken by the majority of other imported proteins, which is characterized by the import involvement of namely, surface receptors, the general insertion protein (GIP), contact sites ...
Berkout, Böhni, Chen, Cheng, Chirico, Daldal, Deshaies, Deshaies, Drygas, Dumont, Dumont, Eilers, Enosawa, Gabellini, Gabellini, Gasser, Hartl, Hartl, Hawlitschek, Hennig, Hennig, Hennig, Horwich, Horwich, Hurt, Hurt, Jordi, Korb, Lewis, Matsuura, McAda, Meyer, Nargang, Nicholson, Nicholson, Nicholson, Nicholson, Pelham, Pfaller, Pfaller, Pfanner, Pfanner, Pfanner, Pfanner, Pollock, Randall, Rietveld, Rietveld, Rietveld, Rietveld, Rietveld, Rothman, Römisch, Sadler, Schleyer, Schleyer, Schwaiger, Smith, Stewart, Stuart, Stuart, Söllner, Teintze, Welch, Zimmermann, Zimmermann, Zitomer, Zwizinski, Zwizinski   +68 more
core   +1 more source

Iron or sulfur respiration—an adaptive choice determining the fitness of a natronophilic bacterium Dethiobacter alkaliphilus in geochemically contrasting environments

Frontiers in Microbiology, 2023
Haloalkaliphilic microorganisms are double extremophiles functioning optimally at high salinity and pH. Their typical habitats are soda lakes, geologically ancient yet widespread ecosystems supposed to harbor relict microbial communities.
Daria G. Zavarzina, Alexander Yu Merkel, Alexandra A. Klyukina, Ivan M. Elizarov, Valeria A. Pikhtereva, Valeria A. Pikhtereva, Vyacheslav S. Rusakov, Nataliya I. Chistyakova, Rustam H. Ziganshin, Alexey A. Maslov, Sergey N. Gavrilov   +10 more
doaj   +1 more source

Pseudomonas Cytochrome c551 at 2.0 angstrom Resolution: Enlargement of the Cytochrome c Family [PDF]

, 1978
The structure of respiratory cytochrome c551 of Pseudomonas aeruginosa, with 82 amino acids, has been solved by x-ray analysis and refined to a crystallographic R factor of 16.2%.
Almassy, Robert J., Dickerson, Richard E.   +1 more
core  

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Efficient and selective isotopic labeling of hemes to facilitate the study of multiheme proteins

BioTechniques, 2012
Specific isotopic labeling of hemes provides a unique opportunity to characterize the structure and function of heme-proteins. Unfortunately, current methods do not allow efficient labeling in high yields of multiheme cytochromes c, which are of great ...
Bruno M. Fonseca, Ming Tien, Mario Rivera, Liang Shi, Ricardo O. Louro   +4 more
doaj   +1 more source

Deep-branching ANME-1c archaea grow at the upper temperature limit of anaerobic oxidation of methane

Frontiers in Microbiology, 2022
In seafloor sediments, the anaerobic oxidation of methane (AOM) consumes most of the methane formed in anoxic layers, preventing this greenhouse gas from reaching the water column and finally the atmosphere.
David Benito Merino, David Benito Merino, Hanna Zehnle, Hanna Zehnle, Hanna Zehnle, Andreas Teske, Gunter Wegener, Gunter Wegener   +7 more
doaj   +1 more source

Resonance Raman Spectroscopy Reveals that Substrate Structure Selectively Impacts the Heme-Bound Diatomic Ligands of CYP17 [PDF]

, 2013
An important function of steroidogenic cytochromes P450 is the transformation of cholesterol to produce androgens, estrogens, and the corticosteroids.
Gregory, Michael C., Kincaid, James R., Mak, Piotr J., Sligar, Stephen G.   +3 more
core   +2 more sources

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Vibrio natriegens as a superior host for the production of c-type cytochromes and difficult-to-express redox proteins

Scientific Reports
C-type cytochromes fulfil many essential roles in both aerobic and anaerobic respiration. Their characterization requires large quantities of protein which can be obtained through heterologous production.
Helena Fuchs, Sophie R. Ullrich, Sabrina Hedrich   +2 more
doaj   +1 more source