Analysis of imatinib in bone marrow and plasma samples of chronic myeloid leukaemia patients using solid phase extraction LC-ESI-MS [PDF]
The LC-ESI-MS was developed and validated for the analysis of imatinib in plasma and bone marrow samples using deuterated imatinib (D(8)-IM) as an internal standard. The biological samples were extracted using Strata-X-C SPE cartridges and separated on C&
Holyoake, T.L. +4 more
core +11 more sources
A genome assembly-integrated dog 1 Mb BAC microarray : a cytogenetic resource for canine cancer studies and comparative genomic analysis [PDF]
Molecular cytogenetic studies have been instrumental in defining the nature of numerical and structural chromosome changes in human cancers, but their significance remains to be fully understood.
Evans, A +7 more
core +2 more sources
Analysis of non-Hodgkin's lymphoma by conventional cytogenetics and fluorescence in-situ hybridisation. [PDF]
Cytogenetic analysis was performed on 40 non-Hodgkin's lymphoma (NHQ node biopsies. Chromosomes X, 3 and 12 were the most frequently gained; of the much rarer monosomies, loss of chromosome 13 was most common.
Hammond, David William, Hammond, D.W.
core +6 more sources
Molecular and classical cytogenetic analyses demonstrate an apomorphic reciprocal chromosomal translocation in Gorilla gorilla [PDF]
The existence of an apomorphic reciprocal chromosomal translocation in the gorilla lineage has been asserted or denied by various cytogeneticists. We employed a new molecular cytogenetic strategy (chromosomal in situ suppression hybridization) combined ...
Stanyon, Roscoe +11 more
core +1 more source
Acute promyelocytic leukemia (APL) is a subtype of acute myeloid leukemia, which is highly aggressive, yet the most curable. It is a medical emergency that requires a very high index of suspicion, as delay in the treatment could lead to fatality.
Shipra Verma +3 more
doaj +1 more source
Prognostic Implications of Cytogenetic Features in Myelodysplastic Syndromes [PDF]
Myelodysplastic Syndromes (MDS) are a heterogeneous group of hematological diseases characterized by refractory cytopenia(s) and variable risk of leukemic progression.
Belli, Carolina Bárbara +3 more
core +1 more source
“Classical cytogenetics” is not equal to “banding cytogenetics” [PDF]
Human cytogenetics is a field suffering from the argumentation that it 'is nowadays really outdated and to be replaced by molecular high throughput approaches'. Thus, it is to be expected that non-cytogeneticists do mistakes in nomenclature of cytogenetics, which is exposed to repeated reforms, like e.g.
openaire +2 more sources
Integration of the cytogenetic and physical maps of chicken chromosome 17 [PDF]
The chicken genome, like those of most avian species, contains numerous microchromosomes that cannot be distinguished by size alone. Unique properties attributed to the microchromosomes include high GC content and gene density, and an enhanced ...
Dodgson, Jerry B +3 more
core +3 more sources
Cervids are characterized by their greatest karyotypic diversity among mammals. A great diversity of chromosome numbers in notably similar morphological groups leads to the existence of several complexes of cryptic species and taxonomic uncertainties ...
Vozdova, Miluse +7 more
core +1 more source
Background Children with Down syndrome (DS) have an enhanced risk of developing acute leukemia, with the most common subtype being acute megakaryoblastic leukemia (AMKL).
Daiane Correa de Souza +8 more
doaj +1 more source

