Results 81 to 90 of about 2,444 (195)

Functional characterization of cytoglobin

open access: yes, 2012
published_or_final_version ; Biological Sciences ; Doctoral ; Doctor of ...
openaire   +2 more sources

Analyzing the role of ferroptosis in ribosome‐related bone marrow failure disorders: From pathophysiology to potential pharmacological exploitation

open access: yesIUBMB Life, Volume 76, Issue 12, Page 1011-1034, December 2024.
Abstract Within the last decade, the scientific community has witnessed the importance of ferroptosis as a novel cascade of molecular events leading to cellular decisions of death distinct from apoptosis and other known forms of cell death. Notably, such non‐ apoptotic and iron‐dependent regulated cell death has been found to be intricately linked to ...
Aliki Papadimitriou‐Tsantarliotou   +3 more
wiley   +1 more source

Nitric oxide in fungi: is there NO light at the end of the tunnel? [PDF]

open access: yes, 2016
Nitric oxide (NO) is a remarkable gaseous molecule with multiple and important roles in different organisms, including fungi. However, the study of the biology of NO in fungi has been hindered by the lack of a complete knowledge on the different ...
Cánovas López, David   +3 more
core   +5 more sources

Cytoglobin modulates myogenic progenitor cell viability and muscle regeneration [PDF]

open access: yesProceedings of the National Academy of Sciences, 2013
Significance Mammalian skeletal muscle is a dynamic and plastic tissue, capable of responding to physiological demands and pathophysiological stresses. This response relies on the muscle’s ability to activate myogenic progenitor cells (MPCs) resulting in myogenesis.
Sarvjeet, Singh   +11 more
openaire   +2 more sources

Haemoglobin Gene Repertoire in Teleost and Cichlid Fishes Shaped by Gene Duplications and Genome Rearrangements

open access: yesMolecular Ecology, Volume 33, Issue 22, November 2024.
ABSTRACT Haemoglobin is a key molecule for oxygen transport in vertebrates. It exhibits remarkable gene diversity in teleost fishes, reflecting adaptation to various aquatic environments. In this study, we present the dynamic evolution of haemoglobin subunit genes based on a comparison of high‐quality genome assemblies of 24 vertebrate species ...
Dmytro Omelchenko   +7 more
wiley   +1 more source

Electron transfer function versus oxygen delivery: a comparative study for several hexacoordinated globins across the animal kingdom. [PDF]

open access: yesPLoS ONE, 2011
Caenorhabditis elegans globin GLB-26 (expressed from gene T22C1.2) has been studied in comparison with human neuroglobin (Ngb) and cytoglobin (Cygb) for its electron transfer properties. GLB-26 exhibits no reversible binding for O(2) and a relatively low
Laurent Kiger   +7 more
doaj   +1 more source

Cytoglobin: A Novel Globin Type Ubiquitously Expressed inVertebrate Tissues [PDF]

open access: yesMolecular Biology and Evolution, 2002
Vertebrates possess multiple respiratory globins that differ in terms of structure, function, and tissue distribution. Three types of globins have been described so far: hemoglobin facilitates the transport of oxygen in the blood, myoglobin serves oxygen transport and storage in the muscle, and neuroglobin has a yet unidentified function in nerve cells.
Thorsten, Burmester   +3 more
openaire   +2 more sources

Diosmin: A promising phytochemical for functional foods, nutraceuticals and cancer therapy

open access: yesFood Science &Nutrition, Volume 12, Issue 9, Page 6070-6092, September 2024.
The anticancer mechanisms of diosmin involve stimulating receptors, increasing ROS, and inducing cell death via the PI3K/Akt pathway. Diosmin upregulates p53 and p21, causing S‐phase cell cycle arrest, and activates caspase‐3, leading to apoptosis. Additionally, diosmin inhibits NF‐κB, reducing inflammation and angiogenesis, and promotes autophagy ...
Lubna Rahman   +7 more
wiley   +1 more source

Characterization of novel glomerular proteins : role in physiology and disease [PDF]

open access: yes, 2014
Glomerular damage accounts for the majority of chronic kidney disease cases, the prevalence of which is dramatically escalating worldwide, mainly due to increase in diabetes and associated nephropathy.
Andersson, Ann-Charlotte
core   +1 more source

Structure, function and the related mechanism of cytoglobin [PDF]

open access: yesSCIENTIA SINICA Vitae, 2018
Cytoglobin (Cygb) is a hemeprotein belonging to the globin superfamily. It is mainly expressed in fibroblasts, cardiomyocytes and vascular smooth muscle cells. The main function of Cygb is unclear. It has been reported that Cygb is involved in oxygen storage, reactive oxygen species detoxification, collagen synthesis, nitric oxide (NO) metabolism ...
XiaoPing LIU, DanLei ZHOU, AiQin LUO
openaire   +1 more source

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