Results 81 to 90 of about 2,444 (195)
Functional characterization of cytoglobin
published_or_final_version ; Biological Sciences ; Doctoral ; Doctor of ...
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Abstract Within the last decade, the scientific community has witnessed the importance of ferroptosis as a novel cascade of molecular events leading to cellular decisions of death distinct from apoptosis and other known forms of cell death. Notably, such non‐ apoptotic and iron‐dependent regulated cell death has been found to be intricately linked to ...
Aliki Papadimitriou‐Tsantarliotou +3 more
wiley +1 more source
Nitric oxide in fungi: is there NO light at the end of the tunnel? [PDF]
Nitric oxide (NO) is a remarkable gaseous molecule with multiple and important roles in different organisms, including fungi. However, the study of the biology of NO in fungi has been hindered by the lack of a complete knowledge on the different ...
Cánovas López, David +3 more
core +5 more sources
Cytoglobin modulates myogenic progenitor cell viability and muscle regeneration [PDF]
Significance Mammalian skeletal muscle is a dynamic and plastic tissue, capable of responding to physiological demands and pathophysiological stresses. This response relies on the muscle’s ability to activate myogenic progenitor cells (MPCs) resulting in myogenesis.
Sarvjeet, Singh +11 more
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ABSTRACT Haemoglobin is a key molecule for oxygen transport in vertebrates. It exhibits remarkable gene diversity in teleost fishes, reflecting adaptation to various aquatic environments. In this study, we present the dynamic evolution of haemoglobin subunit genes based on a comparison of high‐quality genome assemblies of 24 vertebrate species ...
Dmytro Omelchenko +7 more
wiley +1 more source
Electron transfer function versus oxygen delivery: a comparative study for several hexacoordinated globins across the animal kingdom. [PDF]
Caenorhabditis elegans globin GLB-26 (expressed from gene T22C1.2) has been studied in comparison with human neuroglobin (Ngb) and cytoglobin (Cygb) for its electron transfer properties. GLB-26 exhibits no reversible binding for O(2) and a relatively low
Laurent Kiger +7 more
doaj +1 more source
Cytoglobin: A Novel Globin Type Ubiquitously Expressed inVertebrate Tissues [PDF]
Vertebrates possess multiple respiratory globins that differ in terms of structure, function, and tissue distribution. Three types of globins have been described so far: hemoglobin facilitates the transport of oxygen in the blood, myoglobin serves oxygen transport and storage in the muscle, and neuroglobin has a yet unidentified function in nerve cells.
Thorsten, Burmester +3 more
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Diosmin: A promising phytochemical for functional foods, nutraceuticals and cancer therapy
The anticancer mechanisms of diosmin involve stimulating receptors, increasing ROS, and inducing cell death via the PI3K/Akt pathway. Diosmin upregulates p53 and p21, causing S‐phase cell cycle arrest, and activates caspase‐3, leading to apoptosis. Additionally, diosmin inhibits NF‐κB, reducing inflammation and angiogenesis, and promotes autophagy ...
Lubna Rahman +7 more
wiley +1 more source
Characterization of novel glomerular proteins : role in physiology and disease [PDF]
Glomerular damage accounts for the majority of chronic kidney disease cases, the prevalence of which is dramatically escalating worldwide, mainly due to increase in diabetes and associated nephropathy.
Andersson, Ann-Charlotte
core +1 more source
Structure, function and the related mechanism of cytoglobin [PDF]
Cytoglobin (Cygb) is a hemeprotein belonging to the globin superfamily. It is mainly expressed in fibroblasts, cardiomyocytes and vascular smooth muscle cells. The main function of Cygb is unclear. It has been reported that Cygb is involved in oxygen storage, reactive oxygen species detoxification, collagen synthesis, nitric oxide (NO) metabolism ...
XiaoPing LIU, DanLei ZHOU, AiQin LUO
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