Results 61 to 70 of about 1,106 (124)

Stimulation of Cytoglobin Expression and Improvement in ROS-Related Aging Markers in Skin Cells with Tropaeolum majus Extract

Cosmetics
Reactive oxygen species (ROS) and mitochondrial dysfunction play a major role in skin aging. Due to Tropaeolum majus’ suggested protective actions against ROS, a link between T.
Andrea Cipriano, Fang Qi, Karen Kai-Lin Hwang, Priscila Chiavellini, Wei-Chieh Mu, Elodie Aymard, Philippe Schaeffer, Marion Renault, Tanesha Naiken, Emmanuelle Leblanc, Jamila Dhiab, Brigitte Closs, Karl Pays, Delphine Sauce, David Furman, Vittorio Sebastiano, Knut Woltjen, Carine Nizard, Anne-Laure Bulteau   +18 more
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The effect of reactive oxygen and nitrogen species on the structure of cytoglobin: A potential tumor suppressor

Redox Biology, 2018
Many current anti-cancer therapies rely on increasing the intracellular reactive oxygen and nitrogen species (RONS) contents with the aim to induce irreparable damage, which subsequently results in tumor cell death.
Joey De Backer, Jamoliddin Razzokov, Dietmar Hammerschmid, Carl Mensch, Zainab Hafideddine, Naresh Kumar, Geert van Raemdonck, Maksudbek Yusupov, Sabine Van Doorslaer, Christian Johannessen, Frank Sobott, Annemie Bogaerts, Sylvia Dewilde   +12 more
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Effect of cytoglobin overexpression on extracellular matrix component synthesis in human tenon fibroblasts

Biological Research, 2019
Background Conjunctival filtering bleb scar formation is the main reason for the failure of glaucoma filtration surgery. Cytoglobin (Cygb) has been reported to play an important role in extracellular matrix (ECM) remodeling, fibrosis and tissue damage ...
Haiying Wei, Lili Lin, Xiaomei Zhang, Zhuolei Feng, Yeqing Wang, Yan You, Xiaodan Wang, Yongsheng Hou   +7 more
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Cytoglobin as a Marker of Hepatic Stellate Cell-derived Myofibroblasts

Frontiers in Physiology, 2015
Myofibroblasts play important roles in inflammation, fibrosis and tumorigenesis in chronically inflamed liver. Liver myofibroblasts originate from hepatic stellate cells, portal fibroblasts or mesothelial cells, and they are localized in and around ...
Norifumi eKawada
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The novel thiosemicarbazone, di-2-pyridylketone 4-cyclohexyl-4-methyl-3-thiosemicarbazone (DpC), inhibits neuroblastoma growth in vitro and in vivo via multiple mechanisms

Journal of Hematology & Oncology, 2016
Background Neuroblastoma is a relatively common and highly belligerent childhood tumor with poor prognosis by current therapeutic approaches. A novel anti-cancer agent of the di-2-pyridylketone thiosemicarbazone series, namely di-2-pyridylketone 4,4 ...
Zhu-Ling Guo, Des R. Richardson, Danuta S. Kalinowski, Zaklina Kovacevic, Kian Cheng Tan-Un, Godfrey Chi-Fung Chan   +5 more
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An N-myristoylated globin with a redox-sensing function that regulates the defecation cycle in Caenorhabditis elegans.

PLoS ONE, 2012
Globins occur in all kingdoms of life where they fulfill a wide variety of functions. In the past they used to be primarily characterized as oxygen transport/storage proteins, but since the discovery of new members of the globin family like neuroglobin ...
Lesley Tilleman, Sasha De Henau, Martje Pauwels, Nora Nagy, Isabel Pintelon, Bart P Braeckman, Karolien De Wael, Sabine Van Doorslaer, Dirk Adriaensen, Jean-Pierre Timmermans, Luc Moens, Sylvia Dewilde   +11 more
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Hypoxic regulation of cytoglobin and neuroglobin expression in human normal and tumor tissues

Cancer Cell International, 2010
Background Cytoglobin (Cygb) and neuroglobin (Ngb) are recently identified globin molecules that are expressed in vertebrate tissues. Upregulation of Cygb and Ngb under hypoxic and/or ischemic conditions in vitro and in vivo increases cell survival ...
Emara Marwan, Turner A Robert, Allalunis-Turner Joan   +2 more
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Effect of copper nanoparticles exposure in the physiology of the common carp (Cyprinus carpio): Biochemical, histological and proteomic approaches

Aquaculture and Fisheries, 2016
Copper nanoparticles (Cu-NPs) are serious water pollutants but their impact in teleosts performance remains poorly understood. In the present study, we have exposed juvenile carps (Cyprinus carpio), a freshwater teleost edible in India to two different ...
Yugantak Raj Gupta, Durai Sellegounder, Monica Kannan, Seetharam Deepa, Balasubramanian Senthilkumaran, Yaraguntappa Basavaraju   +5 more
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Hemoprotein dalam Tubuh Manusia

Jurnal Kesehatan Andalas, 2012
Abstrak Hemoprotein adalah protein dengan kandungan hem yang terdapat hampir dalam semua sel manusia, hewan, dan pigmen fotosintesis tumbuhan. Ada berbagai macam hemoprotein yang tersebar luas dalam tubuh manusia, seperti hemoglobin, myoglobin ...
Husnil Kadri
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Edaravone and Acetovanillone Upregulate Nrf2 and PI3K/Akt/mTOR Signaling and Prevent Cyclophosphamide Cardiotoxicity in Rats

Drug Design, Development and Therapy, 2020
Emad HM Hassanein,1 Omnia AM Abd El-Ghafar,2 Marwa A Ahmed,3 Ahmed M Sayed,4 Wail M Gad-Elrab,5 Jamaan S Ajarem,6 Ahmed A Allam,7 Ayman M Mahmoud7,8 1Department of Pharmacology and Toxicology Faculty of Pharmacy, Al-Azhar University, Assiut, Egypt ...
Hassanein EHM, Abd El-Ghafar OAM, Ahmed MA, Sayed AM, Gad-Elrab WM, Ajarem JS, Allam AA, Mahmoud AM   +7 more
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