Results 51 to 60 of about 1,106 (124)

Distribution of cytoglobin in the mouse brain

Frontiers in Neuroanatomy, 2016
Cytoglobin (Cygb) is a vertebrate globin with so far poorly defined function. It is expressed in the fibroblast cell-lineage but has also been found in neurons.
Stefan eReuss, Sylvia eWystub, Ursula eDisque-Kaiser, Thomas eHankeln, Thorsten eBurmester   +4 more
doaj   +1 more source

A gene-environment study of cytoglobin in the human and rat hippocampus. [PDF]

PLoS ONE, 2013
BACKGROUND: Cytoglobin (Cygb) was discovered a decade ago as the fourth vertebrate heme-globin. The function of Cygb is still unknown, but accumulating evidence from in vitro studies point to a putative role in scavenging of reactive oxygen species and ...
Christian Ansgar Hundahl, Betina Elfving, Heidi Kaastrup Müller, Anders Hay-Schmidt, Gregers Wegener   +4 more
doaj   +1 more source

Analyzing the role of ferroptosis in ribosome‐related bone marrow failure disorders: From pathophysiology to potential pharmacological exploitation

IUBMB Life, Volume 76, Issue 12, Page 1011-1034, December 2024.
Abstract Within the last decade, the scientific community has witnessed the importance of ferroptosis as a novel cascade of molecular events leading to cellular decisions of death distinct from apoptosis and other known forms of cell death. Notably, such non‐ apoptotic and iron‐dependent regulated cell death has been found to be intricately linked to ...
Aliki Papadimitriou‐Tsantarliotou, Chrysostomos Avgeros, Maria Konstantinidou, Ioannis S. Vizirianakis   +3 more
wiley   +1 more source

Haemoglobin Gene Repertoire in Teleost and Cichlid Fishes Shaped by Gene Duplications and Genome Rearrangements

Molecular Ecology, Volume 33, Issue 22, November 2024.
ABSTRACT Haemoglobin is a key molecule for oxygen transport in vertebrates. It exhibits remarkable gene diversity in teleost fishes, reflecting adaptation to various aquatic environments. In this study, we present the dynamic evolution of haemoglobin subunit genes based on a comparison of high‐quality genome assemblies of 24 vertebrate species ...
Dmytro Omelchenko, Arnold Roger Bitja‐Nyom, Michael Matschiner, Milan Malinsky, Adrian Indermaur, Walter Salzburger, Oldřich Bartoš, Zuzana Musilova   +7 more
wiley   +1 more source

Diosmin: A promising phytochemical for functional foods, nutraceuticals and cancer therapy

Food Science &Nutrition, Volume 12, Issue 9, Page 6070-6092, September 2024.
The anticancer mechanisms of diosmin involve stimulating receptors, increasing ROS, and inducing cell death via the PI3K/Akt pathway. Diosmin upregulates p53 and p21, causing S‐phase cell cycle arrest, and activates caspase‐3, leading to apoptosis. Additionally, diosmin inhibits NF‐κB, reducing inflammation and angiogenesis, and promotes autophagy ...
Lubna Rahman, Ali Talha Khalil, Syed Ahsan Shahid, Zabta Khan Shinwari, Zainab M. Almarhoon, Amnah Alalmaie, Javad Sharifi‐Rad, Daniela Calina   +7 more
wiley   +1 more source

Cardiopulmonary adaptations of a diving marine mammal, the bottlenose dolphin: Physiology during anesthesia

Physiological Reports, Volume 12, Issue 17, September 2024.
Abstract Diving marine mammals are a diverse group of semi‐ to completely aquatic species. Some species are targets of conservation and rehabilitation efforts; other populations are permanently housed under human care and may contribute to clinical and biomedical investigations.
Carolina R. Le‐Bert, Gordon S. Mitchell, Leah R. Reznikov   +2 more
wiley   +1 more source

Electron transfer function versus oxygen delivery: a comparative study for several hexacoordinated globins across the animal kingdom. [PDF]

PLoS ONE, 2011
Caenorhabditis elegans globin GLB-26 (expressed from gene T22C1.2) has been studied in comparison with human neuroglobin (Ngb) and cytoglobin (Cygb) for its electron transfer properties. GLB-26 exhibits no reversible binding for O(2) and a relatively low
Laurent Kiger, Lesley Tilleman, Eva Geuens, David Hoogewijs, Christophe Lechauve, Luc Moens, Sylvia Dewilde, Michael C Marden   +7 more
doaj   +1 more source

A comprehensive review of specific activity and intrinsic connections of food‐derived bioactive peptides for human health

Food Frontiers, Volume 5, Issue 3, Page 1145-1165, May 2024.
This review provides an in‐depth exploration of nineteen types of food‐derived bioactive peptides, focusing on their intricate interplay and foundational functionalities, particularly antioxidant actions, in relation to human health. It emphasizes the complex yet crucial mechanisms of these peptides in various bodily systems and underscores the ...
Tiantian Zhao, Guowan Su, Lijun Zhang, Jieqiong Chen, Yehui Zhang, Weifeng Liu, Mouming Zhao, Jianan Zhang, Qingrong Huang   +8 more
wiley   +1 more source

Iron–histidine bonding in bishistidyl hemoproteins–A local vibrational mode study

Journal of Computational Chemistry, Volume 45, Issue 9, Page 574-588, April 5, 2024.
Using our local mode analysis, the strength of FeN distal and proximal bonds was investigated for bishistidyl proteins from bacteria, animals, human, and plants via local mode force constants ka(FeN). We also investigated the stiffness of the axial NFeN bond angle via local mode force constants ka(NFeN).
Marek Freindorf, Juliana J. Antonio, Elfi Kraka   +2 more
wiley   +1 more source

Phylogenetic analysis reveals wide distribution of globin X

Biology Direct, 2011
The vertebrate globin gene repertoire consists of seven members that differ in terms of structure, function and phyletic distribution. While hemoglobin, myoglobin, cytoglobin, and neuroglobin are present in almost all gnathostomes examined so far, other ...
Makałowski Wojciech, Dröge Jasmin
doaj   +1 more source