Results 41 to 50 of about 1,677 (171)
Hyperthermal stability of neuroglobin and cytoglobin [PDF]
The FEBS Journal, 2005 Neuroglobin (Ngb) and cytoglobin (Cygb), recent additions to the globin family, display a hexa‐coordinated (bis‐histidyl) heme in the absence of external ligands. Although these proteins have the classical globin fold they reveal a very high thermal stability with a melting temperature (Tm) of 100 °C for Ngb and 95 °C for Cygb.
Hamdane, Djemel +7 more
openaire +3 more sources
Role of cytoglobin, a novel radical scavenger, in stellate cell activation and hepatic fibrosis [PDF]
Clinical and Molecular Hepatology, 2020 Cytoglobin (Cygb), a stellate cell-specific globin, has recently drawn attention due to its association with liver fibrosis. In the livers of both humans and rodents, Cygb is expressed only in stellate cells and can be utilized as a marker to distinguish
Le Thi Thanh Thuy +2 more
doaj +1 more source
Phylogeny of Echinoderm Hemoglobins. [PDF]
PLoS ONE, 2015 Recent genomic information has revealed that neuroglobin and cytoglobin are the two principal lineages of vertebrate hemoglobins, with the latter encompassing the familiar myoglobin and α-globin/β-globin tetramer hemoglobin, and several minor groups.
Ana B Christensen +9 more
doaj +1 more source
Neuroglobin and Cytoglobin: Genes, Proteins and Evolution [PDF]
IUBMB Life, 2004 AbstractHemoglobin and myoglobin are oxygen transport and storage proteins of most vertebrates. Neuroglobin (Ngb) and cytoglobin (Cygb) ‐ two recent additions to the vertebrate globin superfamily ‐ have still disputed functions. Combining the data from all available resources, we investigate the evolution of these novel globins.
Thorsten, Burmester +8 more
openaire +2 more sources
Computational and Structural Biotechnology Journal, 2020 While the functions of the recently discovered cytoglobin, ubiquitously expressed in vertebrate tissues, remain uncertain, Antarctic fish provide unparalleled models to study novel protein traits that may arise from cold adaptation.
Daniela Giordano +15 more
doaj +1 more source
Antioxidants, 2022 Despite recent advances in melanoma treatment, there are still patients that either do not respond or develop resistance. This unresponsiveness and/or acquired resistance to therapy could be explained by the fact that some melanoma cells reside in a ...
Joey De Backer +6 more
doaj +1 more source
THE ROLE OF VISFATIN AND CYTOGLOBIN IN OBESE DIABETIC RATS: THE MODULATORY EFFECTS OF RASPBERRY KETONE [PDF]
Bulletin of Pharmaceutical Sciences. Assiut University, 2020 Introduction: Clinical and epidemiological studies suggest that patients who are overweight or obese are more at risk in developing glucose intolerance (G/I) and insulin resistance (I/R) leading to type 2 diabetes (T2DM) and cardiovascular disease.
Hosny Hassan +4 more
doaj +1 more source
Changes of globins expression in tongue sole, Cynoglossus semilaevis (Actinopterygii: Pleuronectiformes: Cynoglossidae) in response to short-term hypoxia [PDF]
Acta Ichthyologica et Piscatoria, 2011 Background. Fishes live in the aquatic systems which are first affected by low or temporally changing O2 availability. Under hypoxia, the fish possess varieties of mechanism to ensure the uptake of an adequate amount of O2.
S. Wang Z. +6 more
doaj +3 more sources
Nitric Oxide Production and Regulation in the Teleost Cardiovascular System
Antioxidants, 2022 Nitric Oxide (NO) is a free radical with numerous critical signaling roles in vertebrate physiology. Similar to mammals, in the teleost system the generation of sufficient amounts of NO is critical for the physiological function of the cardiovascular ...
Daniela Giordano +2 more
doaj +1 more source
Neuroglobin and cytoglobin [PDF]
The EMBO Reports, 2002 Neuroglobin and cytoglobin are two recently discovered members of the vertebrate globin family. Both are intracellular proteins endowed with hexacoordinated heme-Fe atoms, in their ferrous and ferric forms, and display O2 affinities comparable with that of myoglobin.
PESCE, ALESSANDRA +7 more
openaire +4 more sources