Results 21 to 30 of about 1,106 (124)
Antioxidants, 2022 Despite recent advances in melanoma treatment, there are still patients that either do not respond or develop resistance. This unresponsiveness and/or acquired resistance to therapy could be explained by the fact that some melanoma cells reside in a ...
Joey De Backer +6 more
doaj +1 more source
Changes of globins expression in tongue sole, Cynoglossus semilaevis (Actinopterygii: Pleuronectiformes: Cynoglossidae) in response to short-term hypoxia [PDF]
Acta Ichthyologica et Piscatoria, 2011 Background. Fishes live in the aquatic systems which are first affected by low or temporally changing O2 availability. Under hypoxia, the fish possess varieties of mechanism to ensure the uptake of an adequate amount of O2.
S. Wang Z. +6 more
doaj +3 more sources
Nitric Oxide Production and Regulation in the Teleost Cardiovascular System
Antioxidants, 2022 Nitric Oxide (NO) is a free radical with numerous critical signaling roles in vertebrate physiology. Similar to mammals, in the teleost system the generation of sufficient amounts of NO is critical for the physiological function of the cardiovascular ...
Daniela Giordano +2 more
doaj +1 more source
THE ROLE OF VISFATIN AND CYTOGLOBIN IN OBESE DIABETIC RATS: THE MODULATORY EFFECTS OF RASPBERRY KETONE [PDF]
Bulletin of Pharmaceutical Sciences. Assiut University, 2020 Introduction: Clinical and epidemiological studies suggest that patients who are overweight or obese are more at risk in developing glucose intolerance (G/I) and insulin resistance (I/R) leading to type 2 diabetes (T2DM) and cardiovascular disease.
Hosny Hassan +4 more
doaj +1 more source
Phytotherapy Research, Volume 37, Issue 11, Page 4932-4962, November 2023., 2023 Phytochemicals treat liver fibrosis in chemicals induced in‐vivo and in‐vitro liver fibrosis models. MMPs are potential drug targets by novel natural drugs for treating hepatic fibrosis. MMPs regulate ECM turnover, fibrolysis, and stellate cell activation through alternative mechanisms.
Usman Sabir +2 more
wiley +1 more source
Nitric Oxide: Physiological Functions, Delivery, and Biomedical Applications
Advanced Science, Volume 10, Issue 30, October 26, 2023., 2023 This review explores nitric oxide's (NO) roles in physiology and pathology while considering its advantages and limitations. Progress in designing versatile materials as NO donors and carriers for bioavailability and function at target sites is discussed. It summarizes therapeutic potential, challenges, and prospects in biomedicine.
Syed Muntazir Andrabi +6 more
wiley +1 more source
Advanced Science, Volume 10, Issue 26, September 15, 2023., 2023 Programmed cell death mainly include ferroptosis (A), necroptosis (B), and pyroptosis (C), which are morphologically similar and can induce severe inflammatory responses. Notably, ferroptosis, necroptosis, and pyroptosis also participate in the occurrence and development of cancers.
Xudong Zhu, Shenglong Li
wiley +1 more source
MedComm, Volume 4, Issue 4, August 2023., 2023 Patent foramen ovale (PFO), a congenital heart disease causing right‐to‐left shunt, is considered as one etiological factor of neurological chronic diseases with episodic manifestations (NCDEMs). PFO closure can improve NCDEMs and relieve hypoxic state.
Bosi Dong +10 more
wiley +1 more source
F1000Research, 2015 The reaction of hydrogen peroxide with ferric human cytoglobin and a number of distal histidine variants were studied. The peroxidase activity of the monomeric wildtype protein with an internal disulfide bond, likely to be the form of the protein in vivo,
Penny Beckerson +2 more
doaj +1 more source
Pharmaceuticals, 2022 Acute lung injury (ALI) is one of the adverse effects of the antineoplastic agent cisplatin (CIS). Oxidative stress, inflammation, and necroptosis are linked to the emergence of lung injury in various disorders.
Emad H. M. Hassanein +9 more
doaj +1 more source