Results 31 to 40 of about 1,677 (171)

Neuroglobin and cytoglobin as potential enzyme or substrate

Gene, 2007
The possible enzymatic activities of neuro- and cytoglobin as well as their potential function as substrates in enzymatic reactions were studied. Neuro- and cytoglobin are found to show no appreciable superoxide dismutase, catalase, and peroxidase activities.
F. Trandafir, D. Hoogewijs, ALTIERI, Fabio, P. Rivetti Di Val Cervo, K. Ramser, S. Van Doorslaer, J. R. Vanfleteren, L. Moens, S. Dewilde   +8 more
openaire   +5 more sources

Characterization of human cytoglobin gene promoter region

Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression, 2006
Cytoglobin (CYGB) is a member of the vertebrate globin family together with hemoglobin, myoglobin and neuroglobin. Although the physiological function of CYGB is still unclear, spectroscopic studies show that CYGB contains a hexacoordinated heme pocket similar to other pentacoordinated globin proteins.
Guo, X, Philipsen, S, TanUn, KC
openaire   +6 more sources

A gene-environment study of cytoglobin in the human and rat hippocampus. [PDF]

PLoS ONE, 2013
BACKGROUND: Cytoglobin (Cygb) was discovered a decade ago as the fourth vertebrate heme-globin. The function of Cygb is still unknown, but accumulating evidence from in vitro studies point to a putative role in scavenging of reactive oxygen species and ...
Christian Ansgar Hundahl, Betina Elfving, Heidi Kaastrup Müller, Anders Hay-Schmidt, Gregers Wegener   +4 more
doaj   +6 more sources

Cytoglobin and Neuroglobin in the Human Brainstem and Carotid Body

, 2013
The aim of the present study was to evaluate the presence of Neuroglobin (Ngb) and Cytoglobin (Cygb) in the solitary tract nucleus (STN) and in the carotid body of human subjects. Transverse serial sections of formalin-fixed, paraffin-embedded brainstems, taken from six subjects, were investigated.
Di Giulio C, Zara S, De Colli M, Ruffini R, PORZIONATO, ANDREA, MACCHI, VERONICA, DE CARO, RAFFAELE, Cataldi A.   +7 more
openaire   +4 more sources

Transcriptomic and de novo proteomic analyses of organotypic entorhino-hippocampal tissue cultures reveal changes in metabolic and signaling regulators in TTX-induced synaptic plasticity [PDF]

Molecular Brain
Understanding the mechanisms of synaptic plasticity is crucial for elucidating how the brain adapts to internal and external stimuli. A key objective of plasticity is maintaining physiological activity states during perturbations by adjusting synaptic ...
Maximilian Lenz, Paul Turko, Pia Kruse, Amelie Eichler, Zhuo Angel Chen, Juri Rappsilber, Imre Vida, Andreas Vlachos   +7 more
doaj   +2 more sources

Cytoglobin overexpression facilitates proliferation and migration of vascular smooth muscle cells [PDF]

Archives of Biological Sciences, 2020
Cytoglobin, a recently discovered globin, is expressed in vascular smooth muscle cells (VSMCs). Loss of cytoglobin provides a protective effect on vascular reconstruction but the effect of its overexpression is unclear.
Li Lei, Xie Yilin, Li Shen, Tan Juanjuan, Qin Yingchun, Yan Zhiqiang   +5 more
doaj   +1 more source

The expression profile of cytoglobin in human fibrotic lung, and the protective role of cytoglobin in hypoxia and oxidative stress in vitro [PDF]

, 2010
Cytoglobin (CYGB), a novel member of the globin family, has been shown to be upregulated in response to hypoxia, oxidative stress and fibrogenesis. Presented here is evidence of CYGB expression within cells of fibrotic lesions taken from patients with ...
Carpenter, Melinda
core   +7 more sources

Regulation of nitrite reductase and lipid binding properties of cytoglobin by surface and distal histidine mutations [PDF]

Nitric Oxide - Biology and Chemistry, 2022
Anthony W DeMartino, Courtney Sparacino-Watkins, Jesus Tejero   +2 more
exaly   +2 more sources

The Role of Cytoglobin in Cancer

Jurnal Biomedika dan Kesehatan, 2023
Cytoglobin (Cygb) is a new member of the globin protein family, following the discovery of other globin proteins such as hemoglobin (Hb), myoglobin (Mb), and neuroglobin (Ngb). In 2001, Kawada et al. identified Cygb in hepatic stellate cells (HSCs) that play an important role in the repair of damaged liver cell tissue, hence the name stellate cell ...
Deasyka Yastani, Novi Silvia H, Sri Widia A Jusman   +2 more
openaire   +1 more source

Cytoglobin at the Crossroads of Vascular Remodeling [PDF]

Arteriosclerosis, Thrombosis, and Vascular Biology, 2017
Since its discovery ≈15 years ago, cytoglobin has been studied extensively. Because it is found outside the red cell, cytoglobin is categorized as a nonerythroid globin, along with (in humans) proteins, such as myoglobin, neuroglobin, androglobin, and hemoglobin α.
Matthew B, Amdahl, Anthony W, DeMartino, Jesús, Tejero, Mark T, Gladwin   +3 more
openaire   +2 more sources