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Activated T cells and cytokine-induced CD3 + CD56 + killer cells
Annals of Hematology, 1997Over the past two decades, attempts have been made to develop immunotherapy for patients with cancer. A significant obstacle to the development of successful adoptive immunotherapy has been the availability of appropriate cytotoxic cells. Immunologic effector cells such as lymphokine-activated killer (LAK) cells, activated T cells such as tumor ...
G D, Schmidt-Wolf +2 more
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Cytokine Induced Killer (CIK) cells for the treatment of haematological neoplasms
Immunology Letters, 2013Cytokine Induced Killer (CIK) cells are in vitro activated human CD8 T cells which have maintained several characteristics of T-EMRA cells and additionally acquired non specific anti tumoral cytotoxicity and CD56 overexpression, thus representing a cell population with double T and NK phenotype.
M, Introna, J, Golay, A, Rambaldi
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Clinical expansion of cytokine induced killer (CIK) cells
ISBT Science Series, 2012Cytokine induced killer (CIK) cells are polyclonal T cells that can be expanded from marrow or peripheral blood lymphocytes with potent non‐MHC‐restricted cytotoxicity against a variety of tumor target cells. Earlier work had established the superiority of CIK cells over LAK cells in terms expansion and cytotoxicity.
M. B. C. Koh, Y. Ching Linn
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Ultrastructure of cytokine induced human natural killer cells
Cytotherapy, 2019Background & Aim Natural Killer (NK) cells account for 3.66-26.74% of lymphocytes in the human peripheral blood. They secrete exosomes which express both NK-cell markers and cytokines. It has been shown that Interkin-2 (IL-2) stimulated the proliferation of natural killer cells, a sub-class of lymphocytes in human.
W. Ng, D. Tam, D. Liao, W. Lee, F. Chan
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Clinical Studies Applying Cytokine-Induced Killer Cells for the Treatment of Renal Cell Carcinoma
Cancers, 2020Manuel Ritter, Jörg Ellinger
exaly
Autologous cytokine-induced killer cell immunotherapy in lung cancer: a phase II clinical study
Cancer Immunology, Immunotherapy, 2012Xiubao Ren, Hui Li, Jinpu Yu
exaly

