Current status of cytokine-induced killer cells and combination regimens in breast cancer [PDF]
Frontiers in ImmunologyBreast cancer remains a significant health challenge worldwide, with substantial efforts aimed at understanding its pathogenesis, biological characteristics, and clinical triggers.
Yuancong Jiang +3 more
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Cytokine-Induced Killer Cells As Pharmacological Tools for Cancer Immunotherapy [PDF]
Frontiers in Immunology, 2017 Cytokine-induced killer (CIK) cells are a heterogeneous population of effector CD3+CD56+ natural killer T cells, which can be easily expanded in vitro from peripheral blood mononuclear cells.
Xingchun Gao +11 more
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An Exploratory in vitro Study of Cytotoxicity and Cytokine Profiling of Cytokine-Induced Killer (CIK) Cells Against HCT-15 Colorectal Cancer (CRC) Cells [PDF]
ImmunoTargets and TherapySze-Piaw Chin,1,2 Natasha Najwa Nor Arfuzir,1 Vivian Wai-Ping Kong,3 Soon-Keng Cheong1,2 1Department of Research and Development, Cytopeutics Sdn Bhd, Cyberjaya, Selangor, Malaysia; 2M.
Chin SP +3 more
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Biological Character of RetroNectin Activated Cytokine-Induced Killer Cells [PDF]
Journal of Immunology Research, 2016 Adoptive cell therapy (ACT) using autologous cytokine-induced killer (CIK) cells is a promising treatment for metastatic carcinomas. In this study, we investigated the impact of RetroNectin on the proliferation, phenotype alternation, cytokine secretion,
Lu Han +3 more
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Efficient killing of radioresistant breast cancer cells by cytokine-induced killer cells
Tumor Biology, 2017 Recurrence of breast cancer after radiotherapy may be partly explained by the presence of radioresistant cells. Thus, it would be desirable to develop an effective therapy against radioresistant cells. In this study, we demonstrated the intense antitumor
Qingming Guo +8 more
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Revving up natural killer cells and cytokine-induced killer cells against hematological malignancies [PDF]
Frontiers in Immunology, 2015 Natural killer (NK) cells belong to innate immunity and exhibit cytolytic activity against infectious pathogens and tumor cells. NK-cell function is finely tuned by receptors that transduce inhibitory or activating signals, such as killer immunoglobulin ...
Gianfranco ePittari +4 more
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How can Cytokine-induced killer cells overcome CAR-T cell limits [PDF]
Frontiers in Immunology, 2023 The successful treatment of patients affected by B-cell malignancies with Chimeric Antigen Receptor (CAR)-T cells represented a breakthrough in the field of adoptive cell therapy (ACT).
Elisa Cappuzzello +7 more
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Efficacy of modified dendritic cell–cytokine-induced killer cells loaded with tumour stem cell membrane microparticle therapy in the treatment of relapsed or refractory T- and NK-cell lymphoid proliferations and lymphomas: a report of three cases [PDF]
Annals of HematologyThe prognosis of relapsed or refractory T-cell and NK-cell lymphoid proliferations and lymphomas (R/R T/NK-LPD/LYM) remains poor. Modified dendritic cell–cytokine-induced killer (DC–CIK) cells loaded with tumour stem cell (TSC) membrane microparticles ...
Ao Wang +5 more
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Drug Design, Development and Therapy, 2017 Yan Wang,1 Benji Lv,2 Ke Li,3 Anqi Zhang,3 Hong Liu3 1Department of Clinical Laboratory, 2Department of Blood Transfusion, 3Department of Central Laboratory, Liaocheng People’s Hospital, Liaocheng Clinical School of Taishan Medical University ...
Wang Y, Lv BJ, Li K, Zhang AQ, Liu H
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Cytokine-induced killer cells: new insights for therapy of hematologic malignancies [PDF]
Stem Cell Research & TherapyBackground Cytokine-induced killer (CIK) cells are a novel subgroup of immune effectors, classified as one of the modified T cell-mediated arms for immunotherapy.
Faezeh Ghanbari Sevari +4 more
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