Results 21 to 30 of about 3,672,235 (286)

Cytokine Induced Killer Cells as Promising Immunotherapy for Solid Tumors [PDF]

Journal of Cancer, 2011
Cytokine-induced killer (CIK) cells are a heterogeneous subset of ex-vivo expanded T lymphocytes which present a mixed T-NK phenotype and are endowed with a MHC-unrestricted antitumor activity. The main functional properties of CIK cells may address some
Dario Sangiolo
doaj   +3 more sources

Attenuated Cytokine-Induced Memory-Like Natural Killer Cell Responses to Mycobacterium tuberculosis in Tuberculosis Patients

Infection and Drug Resistance, 2023
Chen Liang,1,2,* Shanshan Li,1,* Jinfeng Yuan,1 Yanhua Song,3 Weicong Ren,1 Wei Wang,1 Yuanyuan Shang,1 Shenjie Tang,2 Yu Pang1 1Department of Bacteriology and Immunology, Beijing Key Laboratory on Drug-Resistant Tuberculosis Research, Beijing ...
Liang C, Li S, Yuan J, Song Y, Ren W, Wang W, Shang Y, Tang S, Pang Y   +8 more
doaj   +1 more source

Efficacy of cytokine-induced killer cell infusion as an adjuvant immunotherapy for hepatocellular carcinoma: a systematic review and meta-analysis

Drug Design, Development and Therapy, 2017
Ruili Yu,1 Bo Yang,2 Xiaohua Chi,3 Lili Cai,4 Cui Liu,5 Lei Yang,6 Xueyan Wang,1 Peifeng He,7 Xuechun Lu2 1Department of Allergy, Beijing Shijitan Hospital, Affiliated to Capital Medical University, 2Department of Geriatric Hematology, Chinese PLA ...
Yu R, Yang B, Chi X, Cai L, Liu C, Yang L, Wang X, He P, Lu X   +8 more
doaj   +1 more source

Cytokine-induced killer cells/dendritic cells and cytokine-induced killer cells immunotherapy for the treatment of esophageal cancer: A meta-analysis. [PDF]

Medicine (Baltimore), 2021
Abstract Objectives: This meta-analysis was designed to systematically evaluate whether autologous cytokine-induced killer cells (CIK) or dendritic cells and cytokine-induced killer cells (DC-CIK) immunotherapy combined with chemotherapy can improve the therapeutic effect and safety of chemotherapy in esophageal ...
Yuan X, Zhang AZ, Ren YL, Wang XL, Jiang CH, Yang L, Liu CX, Liang WH, Pang LJ, Gu WY, Li F, Hu JM.   +11 more
europepmc   +5 more sources

Inhibition of human ovarian tumor growth by cytokine-induced killer cells

Archives of Pharmacal Research, 2007
Despite the recent improvement in the treatment of ovarian cancer, this disease is still leading cause of cancer death in women. In this study, the anti-tumor activity of cytokine-induced killer (CIK) cells against human ovarian cancer was evaluated in ...
Gyoonhee Han, G Han, Jong Soon Kang, Jaeseung Lim, K H Yang, Ki Hoon Lee, Hwan Mook Kim, Kyu-Hwan Yang, Song-Kyu Park, Yeon Jin Kim, Song Kyu Park, Youngsoo Kim, Chang Woo Lee, J Lim, Sang-Bae Han, Y J Kim, Kiho Lee, S B Han, Y Kim, Yeo Dae Yoon   +19 more
core   +3 more sources

Cytokine-induced memory-like natural killer cells [PDF]

Proceedings of the National Academy of Sciences, 2009
The mammalian immune response to infection is mediated by 2 broad arms, the innate and adaptive immune systems. Innate immune cells are a first-line defense against pathogens and are thought to respond consistently to infection, regardless of previous exposure, i.e., they do not exhibit memory of prior activation.
Megan A, Cooper, Julie M, Elliott, Peter A, Keyel, Liping, Yang, Javier A, Carrero, Wayne M, Yokoyama   +5 more
openaire   +2 more sources

A dynamic transcriptomic atlas of cytokine-induced killer cells [PDF]

Journal of Biological Chemistry, 2018
Several clinical immunotherapy trials with cytokine-induced killer (CIK) cells have been reported. However, molecular evidence of cell expansion, acquisition of tumor cytotoxicity, and safety of CIK cells is required before putting them to clinical use.
Meng, Mingyao, Li, Lin, Li, Ruhong, Wang, Wenju, Chen, Yang, Xie, Yanhua, Han, Rui, Zhu, Kai, Huang, Wenwen, Yang, Lili, Li, Shuo, Shi, Jianlin, Tan, Weiwei, Gao, Hui, Zhao, Yiyi, Yang, Li, Tan, Jing, Hou, Zongliu   +17 more
openaire   +2 more sources

Dendritic cell/cytokine-induced killer cell-based immunotherapy in lung cancer: What we know and future landscape. [PDF]

, 2020
Multiple modalities for lung cancer therapy have emerged in the past decade, whereas their clinical applications and survival-beneficiary is little known. Vaccination with dendritic cells (DCs) or DCs/cytokine-induced killer (CIK) cells has shown limited
Mohsenzadegan, Monireh, Peng, Ren-Wang, Monireh Mohsenzadegan, Roudi, Raheleh, Raheleh Roudi, Ren‐Wang Peng, Roudi R, Mohsenzadegan M, Peng RW   +8 more
core   +1 more source

Cytotoxic capacity of IL-15-stimulated cytokine-induced killer cells against human acute myeloid leukemia and rhabdomyosarcoma in humanized preclinical mouse models [PDF]

, 2012
Allogeneic stem cell transplantation (allo-SCT) has become an important treatment modality for patients with high-risk acute myeloid leukemia (AML) and is also under investigation for soft tissue sarcomas.
Wels, Winfried, Simone eFulda, Bader, Peter, Eva eRettinger, Koscielniak, Ewa, Winfried eWels, Meyer, Vida, Hermann eKreyenberg, Andreas eVolk, Selim Kuçi, Volk, Andreas, Simone Fulda, Thomas eKlingebiel, Willasch, Andre Manfred, Andreas Volk, Halvard Boenig, Klingebiel, Thomas, Kuçi, Selim, Peter Bader, Eva Rettinger, Thomas Klingebiel, Vida Meyer, Ewa eKoscielniak, Fulda, Simone, Andre eWillasch, Kreyenberg, Hermann, Halvard eBoenig, Bönig, Halvard-Björn, Rettinger, Eva, Vida eMeyer, Hermann Kreyenberg, Peter eBader, Selim eKuci, Ewa Koscielniak, Andre Willasch, Winfried S. Wels   +35 more
core   +1 more source

Cytokine-induced killer cells for cell therapy of acute myeloid leukemia: improvement of their immune activity by expression of CD33-specific chimeric receptors

Haematologica, 2010
Background Cytokine-induced killer cells are ex vivo-expanded cells with potent antitumor activity. The infusion of cytokine-induced killer cells in patients with acute myeloid leukemia relapsing after allogeneic hematopoietic stem cell transplant is ...
Virna Marin, Irene Pizzitola, Valentina Agostoni, Greta Maria Paola Giordano Attianese, Helene Finney, Alastair Lawson, Martin Pule, Raphael Rousseau, Andrea Biondi, Ettore Biagi   +9 more
doaj   +1 more source