Results 11 to 20 of about 127,689 (285)

Cytokine-Induced Killer Cells As Pharmacological Tools for Cancer Immunotherapy [PDF]

open access: yesFrontiers in Immunology, 2017
Cytokine-induced killer (CIK) cells are a heterogeneous population of effector CD3+CD56+ natural killer T cells, which can be easily expanded in vitro from peripheral blood mononuclear cells.
Xingchun Gao   +11 more
doaj   +4 more sources

Cytokine-induced killer cells: A novel treatment for allergic airway inflammation. [PDF]

open access: yesPLoS ONE, 2017
The effectiveness of cytokine-induced killer (CIK) cells for treatment of cancers has long been appreciated. Here, we report for the first time that CIK cells can be applied to treat allergic airway inflammation.
Panwadee Pluangnooch   +3 more
doaj   +6 more sources

Cytokine-induced killer cells are type II natural killer T cells

open access: yesGMS German Medical Science, 2007
Background: Until now, cytokine-induced killer (CIK) cells were assumed to be part of the type I natural killer T (NKT) cell population, but it was not yet investigated if this is correct.
Schmidt-Wolf, Ingo G.H.   +3 more
doaj   +4 more sources

Efficient lysis of rhabdomyosarcoma cells by cytokine-induced killer cells: implications for adoptive immunotherapy after allogeneic stem cell transplantation

open access: yesHaematologica, 2010
Background Rhabdomyosarcoma is the most common soft tissue sarcoma in childhood and has a poor prognosis. Here we assessed the capability of ex vivo expanded cytokine-induced killer cells to lyse both alveolar and embryonic rhabdomyosarcoma cell lines ...
Selim Kuçi   +12 more
doaj   +2 more sources

Efficient killing of radioresistant breast cancer cells by cytokine-induced killer cells

open access: yesTumor Biology, 2017
Recurrence of breast cancer after radiotherapy may be partly explained by the presence of radioresistant cells. Thus, it would be desirable to develop an effective therapy against radioresistant cells. In this study, we demonstrated the intense antitumor
Qingming Guo   +8 more
doaj   +2 more sources

Cytokine-induced killer cells promote antitumor immunity [PDF]

open access: yesJournal of Translational Medicine, 2013
The number of immune cells, especially dendritic cells and cytotoxic tumor infiltrating lymphocytes (TIL), particularly Th1 cells, CD8 T cells, and NK cells is associated with increased survival of cancer patients.
Lu, B   +8 more
core   +4 more sources

Cytokine Induced Killer (CIK) Cells Based Adoptive Immunotherapy

open access: yesJournal of Gandaki Medical College, 2018
Cytokine induced killer (CIK) cells has been increasingly used in adoptive immunotherapy against various cancers and viral infections. This review summarizes the basic overview of CIK cells as a therapeutic immunocyte.
S Timalsena, P P Lamichhane
doaj   +3 more sources

Revving up natural killer cells and cytokine-induced killer cells against hematological malignancies [PDF]

open access: yesFrontiers in Immunology, 2015
Natural killer (NK) cells belong to innate immunity and exhibit cytolytic activity against infectious pathogens and tumor cells. NK-cell function is finely tuned by receptors that transduce inhibitory or activating signals, such as killer immunoglobulin ...
Gianfranco ePittari   +4 more
doaj   +4 more sources

Biological Character of RetroNectin Activated Cytokine-Induced Killer Cells [PDF]

open access: yesJournal of Immunology Research, 2016
Adoptive cell therapy (ACT) using autologous cytokine-induced killer (CIK) cells is a promising treatment for metastatic carcinomas. In this study, we investigated the impact of RetroNectin on the proliferation, phenotype alternation, cytokine secretion,
Lu Han   +3 more
doaj   +3 more sources

Cytokine Induced Killer Cells as Promising Immunotherapy for Solid Tumors [PDF]

open access: yesJournal of Cancer, 2011
Cytokine-induced killer (CIK) cells are a heterogeneous subset of ex-vivo expanded T lymphocytes which present a mixed T-NK phenotype and are endowed with a MHC-unrestricted antitumor activity. The main functional properties of CIK cells may address some
Dario Sangiolo
doaj   +4 more sources

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