Results 31 to 40 of about 116,982 (279)

A dynamic transcriptomic atlas of cytokine-induced killer cells [PDF]

Journal of Biological Chemistry, 2018
Several clinical immunotherapy trials with cytokine-induced killer (CIK) cells have been reported. However, molecular evidence of cell expansion, acquisition of tumor cytotoxicity, and safety of CIK cells is required before putting them to clinical use.
Meng, Mingyao, Li, Lin, Li, Ruhong, Wang, Wenju, Chen, Yang, Xie, Yanhua, Han, Rui, Zhu, Kai, Huang, Wenwen, Yang, Lili, Li, Shuo, Shi, Jianlin, Tan, Weiwei, Gao, Hui, Zhao, Yiyi, Yang, Li, Tan, Jing, Hou, Zongliu   +17 more
openaire   +2 more sources

Cell-based immunotherapy with cytokine-induced killer (CIK) cells: From preparation and testing to clinical application [PDF]

Human Vaccines and Immunotherapeutics, 2017
Guirong Zhang
exaly   +2 more sources

Efficient lysis of rhabdomyosarcoma cells by cytokine-induced killer cells: implications for adoptive immunotherapy after allogeneic stem cell transplantation

Haematologica, 2010
Background Rhabdomyosarcoma is the most common soft tissue sarcoma in childhood and has a poor prognosis. Here we assessed the capability of ex vivo expanded cytokine-induced killer cells to lyse both alveolar and embryonic rhabdomyosarcoma cell lines ...
Selim Kuçi, Eva Rettinger, Bernhard Voß, Gerrit Weber, Miriam Stais, Hermann Kreyenberg, Andre Willasch, Zyrafete Kuçi, Ewa Koscielniak, Stephan Klöss, Dorothee von Laer, Thomas Klingebiel, Peter Bader   +12 more
doaj   +1 more source

Cytokine-induced killer cells/dendritic cells and cytokine-induced killer cells immunotherapy for the treatment of esophageal cancer in China: a meta-analysis

OncoTargets and Therapy, 2017
Immunotherapy based on cytokine-induced killer cells or combination of dendritic cells and cytokine-induced killer cells (CIK/DC-CIK) showed promising clinical outcomes for treating esophageal cancer (EC). However, the clinical benefit varies among previous studies.
Yan Liu, Ying Mu, Anqi Zhang, Shaoda Ren, Weihua Wang, Jiaping Xie, Yingxin Zhang, Changhui Zhou   +7 more
openalex   +5 more sources

MicroRNA profiling of CD3+CD56+ cytokine-induced killer cells [PDF]

Scientific Reports, 2015
AbstractStudies have proven that IL-2 and IL-15 showed contrasting roles during CIK cells preparation. By employing microarray, we analyzed miRNA expression profiles of PBMC, CIKIL-2 and CIKIL-15. Advanced bioinformatic analyses were performed to explore the key miRNAs which may regulate cell proliferation and anti-tumor activity of CIK.
Wenju Wang, Ruhong Li, Mingyao Meng, Chuanyu Wei, Yanhua Xie, Yayong Zhang, Lihong Jiang, Ruiyi Dong, Chunhui Wang, Yiming Zhong, Fang Yang, Weiwei Tang, Xingfang Jin, Baohua Liu, Zongliu Hou   +14 more
openaire   +2 more sources

Cytokine-induced killer cells for cell therapy of acute myeloid leukemia: improvement of their immune activity by expression of CD33-specific chimeric receptors

Haematologica, 2010
Background Cytokine-induced killer cells are ex vivo-expanded cells with potent antitumor activity. The infusion of cytokine-induced killer cells in patients with acute myeloid leukemia relapsing after allogeneic hematopoietic stem cell transplant is ...
Virna Marin, Irene Pizzitola, Valentina Agostoni, Greta Maria Paola Giordano Attianese, Helene Finney, Alastair Lawson, Martin Pule, Raphael Rousseau, Andrea Biondi, Ettore Biagi   +9 more
doaj   +1 more source

Cytokine-induced memory-like natural killer cells for cancer immunotherapy

Stem Cell Research & Therapy, 2021
Natural killer cells are an important part of the innate immune system mediating robust responses to virus-infected and malignant cells without needing prior antigen priming.
Mubin Tarannum, Rizwan Romee
doaj   +1 more source

Novel IL-15 dendritic cells have a potent immunomodulatory effect in immunotherapy of multiple myeloma

Translational Oncology, 2022
Dendritic cells (DCs) are the most potent antigen-presenting cells, and have thus been used in clinical cancer vaccines. However, the effects of DC vaccines are still limited, leading researchers to explore novel ways to make them effective.
Tan-Huy Chu, Manh-Cuong Vo, Thangaraj Jaya Lakshmi, Seo-Yeon Ahn, Mihee Kim, Ga-Young Song, Deok-Hwan Yang, Jae-Sook Ahn, Hyeoung-Joon Kim, Sung-Hoon Jung, Je-Jung Lee   +10 more
doaj   +1 more source

Adjuvant alternative cytokine-induced killer cell combined with natural killer cell immunotherapy improves the prognosis of post-mastectomy breast cancer

Frontiers in Immunology, 2022
Breast cancer is one of the most common cancers in women. Triple-negative breast cancer (TNBC) has a significantly worse prognosis due to the lack of endocrine receptors including estrogen receptor (ER), progesterone receptor (PR) and human epidermal ...
Xinyi Yang, Xinyi Yang, Desheng Weng, Desheng Weng, Qiuzhong Pan, Qiuzhong Pan, Tong Xiang, Tong Xiang, Chaopin Yang, Chaopin Yang, Zhengrong Wu, Minxing Li, Minxing Li, Songzuo Xie, Songzuo Xie, Yan Tang, Yan Tang, Jianchuan Xia, Jianchuan Xia, Jingjing Zhao, Jingjing Zhao   +20 more
doaj   +1 more source

Cytokine Induced Killer (CIK) Cells Based Adoptive Immunotherapy

Journal of Gandaki Medical College, 2018
Cytokine induced killer (CIK) cells has been increasingly used in adoptive immunotherapy against various cancers and viral infections. This review summarizes the basic overview of CIK cells as a therapeutic immunocyte.
S Timalsena, P P Lamichhane
doaj   +1 more source