Results 31 to 40 of about 3,672,235 (286)

Activation of human natural killer cells by Plasmodium falciparum [PDF]

, 2003
The purpose of work described in this thesis was to (i) determine the contribution of innate immune responses to the early pro-inflammatory cytokine response to Plasmodium falciparum, (ii) describe the kinetics and ...
Artavanis-Tsakonas, Katerina
core   +1 more source

MicroRNA profiling of CD3+CD56+ cytokine-induced killer cells [PDF]

Scientific Reports, 2015
AbstractStudies have proven that IL-2 and IL-15 showed contrasting roles during CIK cells preparation. By employing microarray, we analyzed miRNA expression profiles of PBMC, CIKIL-2 and CIKIL-15. Advanced bioinformatic analyses were performed to explore the key miRNAs which may regulate cell proliferation and anti-tumor activity of CIK.
Wenju Wang, Ruhong Li, Mingyao Meng, Chuanyu Wei, Yanhua Xie, Yayong Zhang, Lihong Jiang, Ruiyi Dong, Chunhui Wang, Yiming Zhong, Fang Yang, Weiwei Tang, Xingfang Jin, Baohua Liu, Zongliu Hou   +14 more
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Cytokine-induced memory-like natural killer cells for cancer immunotherapy

Stem Cell Research & Therapy, 2021
Natural killer cells are an important part of the innate immune system mediating robust responses to virus-infected and malignant cells without needing prior antigen priming.
Mubin Tarannum, Rizwan Romee
doaj   +1 more source

Novel IL-15 dendritic cells have a potent immunomodulatory effect in immunotherapy of multiple myeloma

Translational Oncology, 2022
Dendritic cells (DCs) are the most potent antigen-presenting cells, and have thus been used in clinical cancer vaccines. However, the effects of DC vaccines are still limited, leading researchers to explore novel ways to make them effective.
Tan-Huy Chu, Manh-Cuong Vo, Thangaraj Jaya Lakshmi, Seo-Yeon Ahn, Mihee Kim, Ga-Young Song, Deok-Hwan Yang, Jae-Sook Ahn, Hyeoung-Joon Kim, Sung-Hoon Jung, Je-Jung Lee   +10 more
doaj   +1 more source

Efficient killing of radioresistant breast cancer cells by cytokine-induced killer cells

Tumor Biology, 2017
Recurrence of breast cancer after radiotherapy may be partly explained by the presence of radioresistant cells. Thus, it would be desirable to develop an effective therapy against radioresistant cells. In this study, we demonstrated the intense antitumor
Qingming Guo, Danni Zhu, Xiaocui Bu, Xiaofang Wei, Changyou Li, Daiqing Gao, Xiaoqiang Wei, Xuezhen Ma, Peng Zhao   +8 more
doaj   +1 more source

Adjuvant alternative cytokine-induced killer cell combined with natural killer cell immunotherapy improves the prognosis of post-mastectomy breast cancer

Frontiers in Immunology, 2022
Breast cancer is one of the most common cancers in women. Triple-negative breast cancer (TNBC) has a significantly worse prognosis due to the lack of endocrine receptors including estrogen receptor (ER), progesterone receptor (PR) and human epidermal ...
Xinyi Yang, Xinyi Yang, Desheng Weng, Desheng Weng, Qiuzhong Pan, Qiuzhong Pan, Tong Xiang, Tong Xiang, Chaopin Yang, Chaopin Yang, Zhengrong Wu, Minxing Li, Minxing Li, Songzuo Xie, Songzuo Xie, Yan Tang, Yan Tang, Jianchuan Xia, Jianchuan Xia, Jingjing Zhao, Jingjing Zhao   +20 more
doaj   +1 more source

Influence of Cytokines and Autologous Lymphokine-Activated Killer Cells on Leukemic Bone Marrow Cells and Colonies in AML [PDF]

, 2001
We have already shown that cytokine cocktails (IL-1 beta, IL-3, IL-6, SCF, GM-CSF) and/or lymphokine-activated killer (LAK) cells can reduce the amounts of clonal, CD34-positive mononuclear bone marrow cells (BM-MNC) in acute myeloid leukemia (AML).
Gerhartz, Helmut Heinrich, Schmetzer, Helga Maria, Braun, Susanne Walburg   +2 more
core   +1 more source

Blockade of Immunosuppressive Cytokines Restores NK Cell Antiviral Function in Chronic Hepatitis B Virus Infection [PDF]

, 2010
NK cells are enriched in the liver, constituting around a third of intrahepatic lymphocytes. We have previously demonstrated that they upregulate the death ligand TRAIL in patients with chronic hepatitis B virus infection (CHB), allowing them to kill ...
Richard J. Gilson, Dusheiko, G., Gilson, R.J., Dunn Claire, Gilson Richard J., Peppa, D, Patrick T F Kennedy, Ellis, G., Claire Dunn, Celeste Pallant, Dunn, C., Geoffrey Dusheiko, Lorenzo Micco, Dusheiko Geoffrey, Maini Mala K., Micco, L, Ellis, G, Pooja Khanna, Maini, MK, Pallant, C., Micco Lorenzo, Khanna, P, Javaid, A., Gilson, RJ, Micco, L., Mala K Maini, Schurich, A.; id_orcid, Javaid Alia, Khanna Pooja, Schurich, A, Kennedy, P.T.F., Anna Schurich, Pallant, C, Kennedy Patrick T. F., Mala K. Maini, Khanna, P., Peppa Dimitra, Gidon Ellis, Dusheiko, G, Javaid, A, Ellis Gidon, Dimitra Peppa, Dunn, C, Patrick T. F. Kennedy, Pallant Celeste, Maini, M.K., Kennedy, PTF, Alia Javaid, Peppa, D., Schurich Anna, Richard J Gilson   +50 more
core   +1 more source

Presence of the Transmembrane Protein Neuropilin in Cytokine-induced Killer Cells

Anticancer Research, 2020
Cytokine-induced killer (CIK) cells are a heterogenous population of immune cells showing promising applications in immunotherapeutic cancer treatment. Neuropilin (NRP) proteins have been proven to play an important role in cancer development and prognosis.
Diez Garcia De Olalla E. V., Garofano F., Weiher H., Muders M., Forster S., Schmidt-Wolf I. G. H.   +5 more
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Adoptive Cell Therapy of Melanoma with Cytokine-induced Killer Cells [PDF]

Immune Network, 2015
Melanoma is the most aggressive skin cancer and its incidence is gradually increasing worldwide. Patients with metastatic melanoma have a very poor prognosis (estimated 5-year survival rate of
Kim, Ji Sung, Kim, Yong Guk, Pyo, Minji, Lee, Hong Kyung, Hong, Jin Tae, Kim, Youngsoo, Han, Sang-Bae   +6 more
openaire   +2 more sources