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Clinical expansion of cytokine induced killer (CIK) cells
ISBT Science Series, 2012Cytokine induced killer (CIK) cells are polyclonal T cells that can be expanded from marrow or peripheral blood lymphocytes with potent non‐MHC‐restricted cytotoxicity against a variety of tumor target cells. Earlier work had established the superiority of CIK cells over LAK cells in terms expansion and cytotoxicity.
M. B. C. Koh, Y. Ching Linn
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Ultrastructure of cytokine induced human natural killer cells
Cytotherapy, 2019Background & Aim Natural Killer (NK) cells account for 3.66-26.74% of lymphocytes in the human peripheral blood. They secrete exosomes which express both NK-cell markers and cytokines. It has been shown that Interkin-2 (IL-2) stimulated the proliferation of natural killer cells, a sub-class of lymphocytes in human.
W. Ng, D. Tam, D. Liao, W. Lee, F. Chan
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Cytokine-induced Killer Cells: NK-like T Cells with Cytotolytic Specificity against Leukemia
Leukemia and Lymphoma, 2003Kam Hui
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