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Clinical expansion of cytokine induced killer (CIK) cells
ISBT Science Series, 2012Cytokine induced killer (CIK) cells are polyclonal T cells that can be expanded from marrow or peripheral blood lymphocytes with potent non‐MHC‐restricted cytotoxicity against a variety of tumor target cells. Earlier work had established the superiority of CIK cells over LAK cells in terms expansion and cytotoxicity.
M. B. C. Koh, Y. Ching Linn
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Ultrastructure of cytokine induced human natural killer cells
Cytotherapy, 2019Background & Aim Natural Killer (NK) cells account for 3.66-26.74% of lymphocytes in the human peripheral blood. They secrete exosomes which express both NK-cell markers and cytokines. It has been shown that Interkin-2 (IL-2) stimulated the proliferation of natural killer cells, a sub-class of lymphocytes in human.
W. Ng, D. Tam, D. Liao, W. Lee, F. Chan
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Inhibition of human ovarian tumor growth by cytokine-induced killer cells
Archives of Pharmacal Research, 2007Despite the recent improvement in the treatment of ovarian cancer, this disease is still leading cause of cancer death in women. In this study, the anti-tumor activity of cytokine-induced killer (CIK) cells against human ovarian cancer was evaluated in vitro and in vivo.
Hwan Mook, Kim +12 more
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Cytokine-induced Killer Cells: NK-like T Cells with Cytotolytic Specificity against Leukemia
Leukemia and Lymphoma, 2003Kam M Hui
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