Results 31 to 40 of about 71,915 (261)
Chinese Medicine, 2021 Exaggerated immune response and cytokine storm are accounted for the severity of COVID-19, including organ dysfunction, especially progressive respiratory failure and generalized coagulopathy.
Yadong Fan +6 more
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Cytokine Storm as a Cellular Response to dsDNA Breaks: A New Proposal
Frontiers in Immunology, 2021 Pathogenesis of cytokine storm is poorly understood. In this article we propose a new mechanism and suggest innovative therapeutic avenues for its prevention.
Snehal Shabrish, Indraneel Mittra
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High Ferritin in a Critically ill COVID-19 Patient: The Calm before Cytokine Storm [PDF]
Journal of Clinical and Diagnostic Research, 2020 Corona Virus Disease of 2019 (COVID-19) is spreading throughout the world and the United States with confirmed cases in all 50 states. Cytokine Release Syndrome (CRS), or cytokine storm, is being increasingly reported with severe cases of COVID-19 ...
Safa Saki , Mustafa Salam Mawih
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Frontiers in Molecular Biosciences, 2023 The most severe clinical manifestations of the horrifying COVID-19 disease, that claimed millions of lives during the pandemic time, were Acute respiratory distress syndrome (ARDS), Coagulopathies, septic shock leading eventually to death.
Vikram Kumar +10 more
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Increase in Vascular Endothelial Growth Factor (VEGF) Expression and the Pathogenesis of iMCD-TAFRO
BiomedicinesTAFRO (thrombocytopenia (T), anasarca (A), fever (F), reticulin fibrosis (F/R), renal failure (R), and organomegaly (O)) is a heterogeneous clinical subtype of idiopathic multicentric Castleman disease (iMCD) associated with a significantly poorer ...
Gordan Srkalovic +3 more
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The mechanistic basis linking cytokine storm to thrombosis in COVID-19
Thrombosis Update, 2022 It is now well established that infection with SARS-CoV-2 resulting in COVID-19 disease includes a severely symptomatic subset of patients in whom an aggressive and/or dysregulated host immune response leads to cytokine storm syndrome (CSS) that may be ...
Adam Wolf +10 more
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Breast-implant associated unicentric castleman disease: a case report
Current Problems in Cancer: Case ReportsALK-negative anaplastic large cell lymphoma is a well-established hematologic complication of prosthetic breast implantation, but other rare conditions should also be considered.
Saishravan Shyamsundar +12 more
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Galectin-8, cytokines, and the storm [PDF]
Biochemical Society Transactions, 2021 Galectin-8 (Gal-8) belongs to a family of animal lectins that modulate cell adhesion, cell proliferation, apoptosis, and immune responses. Recent studies have shown that mammalian Gal-8 induces in an autocrine and paracrine manner, the expression and secretion of cytokines and chemokines such as RANKL, IL-6, IL-1β, SDF-1, and MCP-1. This involves Gal-8
openaire +2 more sources
Cytokine Storm—Definition, Causes, and Implications
International Journal of Molecular Sciences, 2022 The human innate and adaptive immune systems consist of effector cells producing cytokines (interleukins, interferons, chemokines, and numerous other mediators). Usually, a fragile equilibrium of pro- and anti-inflammation effects is maintained by complex regulatory mechanisms.
Dominik Jarczak, Axel Nierhaus
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HaematologicaIdiopathic multicentric Castleman disease (iMCD) is a rare hematologic disorder with heterogeneous presentations ranging from moderate constitutional symptoms to life-threatening multiorgan system involvement. iMCD patients present with vastly different
Mateo Sarmiento Bustamante +12 more
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