Results 201 to 210 of about 86,839 (276)

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, Volume 16, Issue 5, Page 821-836, May 2026.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Severe Adult HLH/MAS With SPTCL‐Like Panniculitis: A Phenotype‐Guided, Resource‐Adapted Therapeutic Strategy Without Cytotoxic Therapy

Clinical Case Reports, Volume 14, Issue 5, -Not available-.
Graphical abstract illustrating the phenotype‐guided therapeutic approach in severe adult HLH/MAS with SPTCL‐like panniculitis, demonstrating clinical and biochemical response following sequential treatment with therapeutic plasma exchange, intravenous immunoglobulin, and cyclosporine.
Hatem Mousa Taha, Omar Marouf, Khaled Hatem Taha   +2 more
wiley   +1 more source

Secondary Dengue Infection Presenting With Kawasaki Disease–Like Features: A Diagnostic Dilemma in a 12‐Year‐Old Girl

Clinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT In dengue‐endemic regions, prolonged fever with mucocutaneous findings may represent classical Kawasaki disease (KD), dengue‐associated KD‐like inflammation, or true concomitant disease. When KD cannot be confidently excluded, timely IVIG administration may be justified to prevent coronary complications.
Saad Bin Toufeeq, Ammara Arshad, Nabeel Ahmad, Ali Bin Toufeeq, Ahmad Sama, Neykzad Wadeer   +5 more
wiley   +1 more source

Confronting the controversy: interleukin-6 and the COVID-19 cytokine storm syndrome. [PDF]

Eur Respir J, 2020
Chen LYC, Hoiland RL, Stukas S, Wellington CL, Sekhon MS.   +4 more
europepmc   +1 more source

Hemophagocytic Lymphohistiocytosis Triggered by Legionella pneumophila and SARS‐CoV‐2 Infection in GATA2 Deficiency

Clinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT Germline GATA2 deficiency predisposes to bone marrow failure, myeloid neoplasia, and immune dysregulation. The syndrome is often complicated by infection with intracellular pathogens and viruses, autoimmunity, and inflammation. Hemophagocytic lymphohistiocytosis (HLH) is a rare occurrence that can present further management challenges.
Harry Wilson, Nuno Borges, Matthew Collin, Callum Wright   +3 more
wiley   +1 more source

Secoisolariciresinol Diglucoside Alleviates LPS‐Induced Acute Lung Injury by Inhibiting the NF‐κB/NLRP3 Signaling Pathway

Drug Development Research, Volume 87, Issue 3, May 2026.
ABSTRACT Acute lung injury (ALI) and its more severe form, acute respiratory distress syndrome (ARDS), are life‐threatening pulmonary disorders with high mortality rates, and effective treatments are currently lacking. Secoisolariciresinol diglucoside (SDG), a plant lignan derived from flaxseed, possesses anti‐inflammatory and antioxidative activities.
Yuanyuan Zhong, Yang Zou, Zhen Qu, Kai Zhou, Huijuan Liu, Jiali Yang, Chengzhong Tang, Yuqiang Xu, Zhen Wang   +8 more
wiley   +1 more source

Tocilizumab for cytokine storm syndrome in COVID-19 pneumonia: an increased risk for candidemia? [PDF]

Autoimmun Rev, 2020
Antinori S, Bonazzetti C, Gubertini G, Capetti A, Pagani C, Morena V, Rimoldi S, Galimberti L, Sarzi-Puttini P, Ridolfo AL.   +9 more
europepmc   +1 more source

Intersecting Molecular Pathways in Cardiovascular Disease and Diabetes Mellitus: Emerging Roles of Inflammation and Therapeutics

Diabetes/Metabolism Research and Reviews, Volume 42, Issue 4, May 2026.
Central illustration: Pathophysiological mechanisms linking diabetes mellitus and cardiovascular disease. Chronic hyperglycaemia, insulin resistance, and low‐grade inflammation contribute to endothelial dysfunction, myocardial fibrosis, and cardiomyocyte apoptosis.
Lilian Anagnostopoulou, Nikolaos Ktenopoulos, Anastasios Apostolos, Christos Fragoulis, Panayotis Vlachakis, Paschalis Karakasis, Marios Sagris, Nikias Milaras, Maria Drakopoulou, Andreas Synetos, Ioannis Kyriazis, Ioannis Ioannidis, Costas Tsioufis, Konstantinos Toutouzas   +13 more
wiley   +1 more source

The Inversion of IL-6 Levels in Relation to C-Reactive Protein as the Marker for Cytokine Storm Syndrome in COVID-19

, 2022
Filho SPdMM, Martins FS, Giroldi PJ, Melo RHe, Oliveira ELd, Santos ABd, Medeiros DCO, Basano SdA, Lopes JA, Chaves YO, Camargo LMA, Zuliane JP, Nogueira PA.   +12 more
europepmc   +1 more source

Rapid Radiological Worsening and Cytokine Storm Syndrome in COVID-19 Pneumonia. [PDF]

Eur J Case Rep Intern Med, 2020
Ruch Y, Kaeuffer C, Guffroy A, Lefebvre N, Hansmann Y, Danion F.   +5 more
europepmc   +1 more source