Case Report: Tocilizumab for the Treatment of SARS-CoV-2 Infection in a Patient With Aplastic Anemia
Frontiers in Oncology, 2020 While cytokine storm develops in a minority of patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, novel treatment approaches are desperately needed for those in whom it does.
Gina Keiffer +5 more
doaj +1 more source
Bioengineering & Translational Medicine, 2023 Cytokine storm is a phenomenon whereby the overreaction of the human immune system leads to the release of inflammatory cytokines, which can lead to multiple organ dysfunction syndrome.
Hengfeng Liao +12 more
doaj +1 more source
Frontiers in Bioengineering and Biotechnology, 2021 Coronavirus is a family of viruses including alpha-, beta-, gamma-, delta-coronaviruses. Only alpha- and betacoronaviruses have been observed to infect humans.
Olanrewaju B. Morenikeji +4 more
doaj +1 more source
Virological aspects of Epstein-Barr virus infections. [PDF]
, 2005 Epstein-Barr virus (EBV) is usually maintained in an asymptomatic and latent form by the host immune system, and primarily by EBV-specific cytotoxic T cells (CTLs).
Kimura, Hiroshi +2 more
core +1 more source
Role of cytokine storm in coronavirus infections: culprit or accomplice?
Frontiers in Bioscience-Landmark, 2022 At present, there are seven known types of human coronaviruses (HCoVs), which can be further divided into two categories: low pathogenic and highly pathogenic.
Rongpeng Xu +5 more
doaj +1 more source
High Ferritin in a Critically ill COVID-19 Patient: The Calm before Cytokine Storm [PDF]
Journal of Clinical and Diagnostic Research, 2020 Corona Virus Disease of 2019 (COVID-19) is spreading throughout the world and the United States with confirmed cases in all 50 states. Cytokine Release Syndrome (CRS), or cytokine storm, is being increasingly reported with severe cases of COVID-19 ...
Safa Saki , Mustafa Salam Mawih
doaj +1 more source
Interference of the T cell and antigen-presenting cell costimulatory pathway using CTLA4-Ig (abatacept) prevents Staphylococcal enterotoxin B pathology [PDF]
, 2017 Staphylococcal enterotoxin B (SEB) is a bacterial superantigen that binds the receptors in the APC/T cell synapse and causes increased proliferation of T cells and a cytokine storm syndrome in vivo.
Carter, Alun J +10 more
core +2 more sources
A brief overview of current drug repurposing approaches for COVID-19 management [PDF]
, 2020 This brief overview is intended to shed light on the current drug repositioning (also called drug repurposing) in the therapeutics of the novel coronavirus disease which emerged in 2019 (COVID-19).
Rodrigues, Pedro da Fonseca Soares +1 more
core +2 more sources
A New Investigation into the Molecular Mechanism of Andrographolide towards Reducing Cytokine Storm
Molecules, 2022 Cytokine storm is a condition in which the immune system produces an excessive number of inflammatory signals, which can result in organ failure and death.
Abdulaziz Alzahrani
doaj +1 more source
Tocilizumab as a Treatment for ‘Cytokine Storm Syndrome’ in COVID-19: A Case Report
Acta Medica Indonesiana, 2021 Coronavirus disease 19 (COVID-19) which is caused by Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), has been a problem worldwide, particularly due to the high rate of transmission and wide range of clinical manifestations.
Ari Fahrial Syam +13 more
doaj