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Behavior of tumors under nonstationary theraphy [PDF]

open access: yes, 2002
We present a model for the interaction dynamics of lymphocytes-tumor cells population. This model reproduces all known states for the tumor. Futherly,we develop it taking into account periodical immunotheraphy treatment with cytokines alone. A detailed analysis for the evolution of tumor cells as a function of frecuency and theraphy burden applied for ...
Bell   +16 more
arxiv   +3 more sources

Expression of SARS-CoV-2 Spike Protein Receptor Binding Domain on Recombinant B. subtilis on Spore Surface: A Potential COVID-19 Oral Vaccine Candidate

open access: yesVaccines, 2021
Various types of vaccines, such as mRNA, adenovirus, and inactivated virus by injection, have been developed to prevent SARS-CoV-2 infection. Although some of them have already been approved under the COVID-19 pandemic, various drawbacks, including ...
Johnny Chun-Chau Sung   +11 more
doaj   +1 more source

Retraction: Sung et al. Expression of SARS-CoV-2 Spike Protein Receptor Binding Domain on Recombinant B. subtilis on Spore Surface: A Potential COVID-19 Oral Vaccine Candidate. Vaccines 2022, 10, 2

open access: yesVaccines, 2022
The journal retracts the article “Expression of SARS-CoV-2 Spike Protein Receptor Binding Domain on Recombinant B. subtilis on Spore Surface: A Potential COVID-19 Oral Vaccine Candidate” [...]
Johnny Chun-Chau Sung   +11 more
doaj   +1 more source

Oral Vaccines: A Better Future of Immunization

open access: yesVaccines, 2023
Oral vaccines are gaining more attention due to their ease of administration, lower invasiveness, generally greater safety, and lower cost than injectable vaccines. This review introduces certified oral vaccines for adenovirus, recombinant protein-based,
Keith Wai-Yeung Kwong   +7 more
doaj   +1 more source

The Antiviral Activities of Poly-ADP-Ribose Polymerases

open access: yesViruses, 2021
The poly-adenosine diphosphate (ADP)-ribose polymerases (PARPs) are responsible for ADP-ribosylation, a reversible post-translational modification involved in many cellular processes including DNA damage repair, chromatin remodeling, regulation of ...
Mathilde Malgras   +4 more
doaj   +1 more source

Safety and Immunogenicity of Inactivated Bacillus subtilis Spores as a Heterologous Antibody Booster for COVID-19 Vaccines

open access: yesVaccines, 2022
The coronavirus diseases 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections have threatened the world for more than 2 years.
Johnny Chun-Chau Sung   +12 more
doaj   +1 more source

Phenol-soluble modulins α are major virulence factors of Staphylococcus aureus secretome promoting inflammatory response in human epidermis

open access: yesVirulence, 2021
Staphylococcus aureus is a skin commensal microorganism commonly colonizing healthy humans. Nevertheless, S. aureus can also be responsible for cutaneous infections and contribute to flare-up of inflammatory skin diseases such as atopic dermatitis (AD ...
Alexia Damour   +11 more
doaj   +1 more source

IL-17 and IL-22 are pivotal cytokines to delay wound healing of S. aureus and P. aeruginosa infected skin

open access: yesFrontiers in Immunology, 2022
IntroductionAlthough the presence of pathogens in skin wounds is known to delay the wound healing process, the mechanisms underlying this delay remain poorly understood.
Jean-Claude Lecron   +23 more
doaj   +1 more source

Mechanism of co-operation of mutant IL-7Rα and mutant NRAS in acute lymphoblastic leukemia: role of MYC

open access: yesHaematologica, 2023
Acute lymphoblastic leukemia (ALL) is an aggressive leukemia which can be derived from either T-cell or B-cell precursors. With current treatments, the survival rate is high, but the treatments are highly toxic with severe side effects.
Hila Winer   +6 more
doaj   +1 more source

Assessment of novel antiviral filter using pseudo-type SARS-CoV-2 virus in fast air velocity vertical-type wind tunnel

open access: yesScientific Reports, 2023
Current evidence suggests that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can remain suspended spread in aerosols for longer period of time under poorly ventilated indoor setting.
Johnny Chun-Chau Sung   +6 more
doaj   +1 more source

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