Results 1 to 10 of about 887,192 (199)
Mediators of Inflammation, 2014 Recent evidence in biology and medicine has expanded the knowledge of cytokines function in many disease states and conditions as well as the severe adverse effects implicated in the escalated production associated with specific disease conditions.
Arkadiusz Orzechowski +3 more
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Engineering cytokines and cytokine circuits
Science, 2020 Learning to speak the secret language of immune cells could improve ...
Wendell A. Lim, Aileen W. Li
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Cytokine Modulation of Keratinocyte Cytokines
Journal of Investigative Dermatology, 1990 There is increasing evidence that epidermal cytokines may have an important role in mediating inflammatory and immune responses in the skin. A number of cell types in the epidermis are capable of secreting cytokines including keratinocytes, Langerhans cells, melanocytic cells, and even Merkle cells.
Stephen H. Hefeneider +7 more
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Seizure, 2011 Epilepsy is a common chronic neurological disorder affecting approximately 8 out of 1000 people. Its pathophysiology, however, has remained elusive in many regards. Consequently, adequate seizure control is still lacking in about one third of patients. Cytokines are soluble mediators of cell communication that are critical in immune regulation.
Braxton A. Norwood +8 more
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Immunity, 2019 Asthma is a chronic inflammatory airway disease associated with type 2 cytokines interleukin-4 (IL-4), IL-5, and IL-13, which promote airway eosinophilia, mucus overproduction, bronchial hyperresponsiveness (BHR), and immunogloubulin E (IgE) synthesis. However, only half of asthma patients exhibit signs of an exacerbated Type 2 response.
Hamida Hammad +3 more
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International Journal of Obesity, 1998 Cytokines inhibit feeding through peripheral and brain mechanisms. Behavioral, cellular, and molecular studies show that interactions among cytokines, neurotransmitters, and peptides and modulation of hypothalamic neurons are involved in cytokine-induced feeding inhibition.
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Cytokines and autoimmunity [PDF]
Clinical and Experimental Immunology, 1994 SUMMARYAlthough the immunopathology of most autoimmune diseases has been well defined, the mechanisms responsible for the breakdown of self-tolerance and which lead to the development of systematic and organ-specific autoaggression are still unclear. Evidence has accumulated which supports a role for a disregulated production of cytokines by leucocytes
CAVALLO, Maria Gisella +2 more
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Current Opinion in Immunology, 1992 The past few years have witnessed exciting developments regarding the role of cytokines in autoimmune diseases, particularly in rheumatoid arthritis and Crohn's disease, with the demonstration that anti-TNF alpha therapy is clinically beneficial and provides reproducible results.
Brennan, F, Feldmann, M
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Brazilian Journal of Anesthesiology, 2011 Cytokines are necessary for the inflammatory response, favoring proper wound healing. However, exaggerated proinflammatory cytokine production can manifest systemically as hemodynamic instability or metabolic derangements. The objective of this review was to describe the effects of cytokines in pain.This article reviews the effects of cytokines in pain.
Rioko Kimiko Sakata +4 more
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Cell, 2008 IL17RA or IL17RCTh17 cells and others Mucosal tissues, epithelial and endothelial cells Proinflammatory; protective immunity in lung; tight junction integrity; promotes mobilization of neutrophils and cytokine production by epithelial cells; promotes angiogenesis↓ = susceptibility to extracellular pathogens↑ = exacerbates organ-specific autoimmune ...
Daniel J. Cua, Cristina M. Tato
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