Results 31 to 40 of about 1,732,574 (287)

H3K4me1 Supports Memory-like NK Cells Induced by Systemic Inflammation

Cell Reports, 2019
Summary: Natural killer (NK) cells are unique players in innate immunity and, as such, an attractive target for immunotherapy. NK cells display immune memory properties in certain models, but the long-term status of NK cells following systemic ...
Orhan Rasid, Christine Chevalier, Tiphaine Marie-Noelle Camarasa, Catherine Fitting, Jean-Marc Cavaillon, Melanie Anne Hamon   +5 more
doaj   +1 more source

Anti-SARS-CoV-2 Activity of Polysaccharides Extracted from Halymenia floresii and Solieria chordalis (Rhodophyta)

Marine Drugs, 2023
Even after hundreds of clinical trials, the search for new antivirals to treat COVID-19 is still relevant. Carrageenans are seaweed sulfated polysaccharides displaying antiviral activity against a wide range of respiratory viruses.
Clément Jousselin, Hugo Pliego-Cortés, Alexia Damour, Magali Garcia, Charles Bodet, Daniel Robledo, Nathalie Bourgougnon, Nicolas Lévêque   +7 more
doaj   +1 more source

Immunological relationships during primary infection with Heligmosomoides polygyrus (Nematospiroides dubius): downregulation of specific cytokine secretion (IL-9 and IL-10) correlates with poor mastocytosis and chronic survival of adult worms [PDF]

, 1993
Mice were infected either with Trichinella spiralis (day 0), Heligmosomoides polygyrus (day -14) or concurrently with both species and were killed in groups, together with naive control mice, on 2 occasions (day 8 and 15 post infection with T.
Behnke, Jerzy M., Ben-Smith, A.W., Else, K.J., Goyal, P.K., Grencis, R.K., Wahid, F.N.   +5 more
core   +2 more sources

The fiendish behavior of TNF can be counteracted by microRNA

EMBO Molecular Medicine, 2015
Tumor necrosis factor (TNF) is a fascinating anti‐tumoral cytokine, which plays a key role in orchestrating the fight of innate immunity against infection.
Jean‐Marc Cavaillon
doaj   +1 more source

Acute Simian Immunodeficiency Virus Infection Triggers Early and Transient Interleukin-7 Production in the Gut, Leading to Enhanced Local Chemokine Expression and Intestinal Immune Cell Homing

Frontiers in Immunology, 2017
The intestinal barrier, one of the first targets of HIV/simian immunodeficiency virus (SIV) is subjected to major physiological changes during acute infection.
Rosalie Ponte, Rosalie Ponte, Rosalie Ponte, Magali Rancez, Magali Rancez, Magali Rancez, Suzanne Figueiredo-Morgado, Suzanne Figueiredo-Morgado, Suzanne Figueiredo-Morgado, Jacques Dutrieux, Jacques Dutrieux, Jacques Dutrieux, Véronique Fabre-Mersseman, Véronique Fabre-Mersseman, Véronique Fabre-Mersseman, Bénédicte Charmeteau-de-Muylder, Bénédicte Charmeteau-de-Muylder, Bénédicte Charmeteau-de-Muylder, Thomas Guilbert, Thomas Guilbert, Thomas Guilbert, Jean-Pierre Routy, Rémi Cheynier, Rémi Cheynier, Rémi Cheynier, Anne Couëdel-Courteille, Anne Couëdel-Courteille, Anne Couëdel-Courteille, Anne Couëdel-Courteille   +28 more
doaj   +1 more source

Mechanisms underlying bone loss associated with gut inflammation [PDF]

, 2019
Patients with gastrointestinal diseases frequently suffer from skeletal abnormality, characterized by reduced bone mineral density, increased fracture risk, and/or joint inflammation.
Abu-Amer, Yousef, Arra, Manoj, Ke, Ke
core   +2 more sources

Amyloid beta and diabetic pathology cooperatively stimulate cytokine expression in an Alzheimer's mouse model [PDF]

, 2020
Background Diabetes is a risk factor for developing Alzheimer's disease (AD); however, the mechanism by which diabetes can promote AD pathology remains unknown.
Fernández Ponce, Cecilia Matilde, García Alloza, Mónica, Hierro-Bujalance, Carmen, Infante-Garcia, Carmen, Ramos-Rodríguez, Juan José, Sankar, Sitara B., Weinstock, Laura D., Wood, Levi B.   +7 more
core   +3 more sources

Microarray analyses demonstrate the involvement of type i interferons in psoriasiform pathology development in D6-deficient mice [PDF]

, 2013
The inflammatory response is normally limited by mechanisms regulating its resolution. In the absence of resolution, inflammatory pathologies can emerge, resulting in substantial morbidity and mortality.
Baldwin, H.M., Carballido, J.M., Graham, G.J., Jamieson, T., Jaritz, M., King, V., McKimmie, C.S., Nibbs, R.J.B., Pallas, K., Rot, A.   +9 more
core   +1 more source

Cytokines Modulate the “Immune-Metabolism” Interactions during Behçet Disease: Effect on Arginine Metabolism

International Journal of Inflammation, 2015
Aim and Methods. In this study, we evaluated NOS and arginase activities and their regulation during Behçet disease, a systemic chronic inflammatory disorder with uncertain etiology.
Houda Belguendouz, Karima Lahmar-Belguendouz, Djamel Messaoudene, Zineb Djeraba, Fifi Otmani, Djennat Hakem, Ouided S. Lahlou-Boukoffa, Pierre Youinou, Chafia Touil-Boukoffa   +8 more
doaj   +1 more source

Intravitreal GD2‐Specific Chimeric Antigen Receptor T‐Cell Therapy for Refractory Retinoblastoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Effective treatments for advanced, treatment‐resistant retinoblastoma (RB) remain limited. GD2‐specific chimeric antigen receptor (CAR) T cells show potent antitumor activity with minimal toxicity but have not previously been evaluated in RB.
Subongkoch Subhadhirasakul, Jatuporn Sujjitjoon, Pa‐thai Yenchitsomanus, Kridtin Jarutatsanangkoon, Ng Wei Loon, Kleebsabai Sanpakit, Jassada Buaboonnam, Chayamon Takpradit, Pornpimon Yuti, Nunghathai Sawasdee, Piriya Luangwattananun, Siripakorn Sangkitporn, Arnan Limmahachai, La‐ongsri Atchaneeyasakul   +13 more
wiley   +1 more source