Results 21 to 30 of about 1,145,654 (269)
The importance of selected biomarkers in the clinical practice of breast cancer patients
Nowotwory, 2023 Breast cancer is considered the most commonly diagnosed tumors. Biomarkers used for the diagnosis and treatment of breast cancer are: tissue biomarkers (PR, ER, HER2, Ki-67) and serum biomarkers (CA-15-3, CA-125, CA-27-29, CEA, cytokeratins).
Agata Makówka, Beata Kotowicz
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Frontiers in Immunology, 2022 IL-1 plays a crucial role in triggering sterile inflammation following tissue injury. Although most studies associate IL-1 release by injured cells to the recruitment of neutrophils for tissue repair, the inflammatory cascade involves several molecular ...
Sevda Cordier-Dirikoc +11 more
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Antiviral and Immunomodulatory Properties of Antimicrobial Peptides Produced by Human Keratinocytes
Frontiers in Microbiology, 2020 Keratinocytes, the main cells of the epidermis, are the first site of replication as well as the first line of defense against many viruses such as arboviruses, enteroviruses, herpes viruses, human papillomaviruses, or vaccinia virus.
Céline Chessa +9 more
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Cytokine-Mediated Crosstalk Between Keratinocytes and T Cells in Atopic Dermatitis
Frontiers in Immunology, 2022 Atopic dermatitis (AD) is a chronic inflammatory skin disease characterized by barrier dysfunction, dysregulated immune response, and dysbiosis with increased Staphylococcus aureus colonization. Infiltration of various T helper cell subsets into lesional
Mélanie Humeau +2 more
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Engineering cytokines and cytokine circuits
Science, 2020 Learning to speak the secret language of immune cells could improve ...
Aileen W, Li, Wendell A, Lim
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Specific features of human monocytes activation by monophosphoryl lipid A
Scientific Reports, 2018 We deciphered the mechanisms of production of pro- and anti-inflammatory cytokines by adherent human blood mononuclear cells (PBMC) activated by lipopolysaccharide (LPS) or monophosphoryl lipid A (MPLA).
Ryme Chentouh +2 more
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IL-7-Adjuvanted Vaginal Vaccine Elicits Strong Mucosal Immune Responses in Non-Human Primates
Frontiers in Immunology, 2021 Mucosal immune responses are crucial in protecting against pathogens entering through mucosal surfaces. However, due to poor T-cell responsiveness upon mucosal antigenic stimulation, mucosal immunity remains difficult to obtain through vaccines and ...
Sandrine Logerot +9 more
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Mediators of Inflammation, 2014 Recent evidence in biology and medicine has expanded the knowledge of cytokines function in many disease states and conditions as well as the severe adverse effects implicated in the escalated production associated with specific disease conditions.
Arkadiusz Orzechowski +3 more
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Cytokines and autoimmunity [PDF]
Clinical and Experimental Immunology, 1994 SUMMARYAlthough the immunopathology of most autoimmune diseases has been well defined, the mechanisms responsible for the breakdown of self-tolerance and which lead to the development of systematic and organ-specific autoaggression are still unclear. Evidence has accumulated which supports a role for a disregulated production of cytokines by leucocytes
CAVALLO, Maria Gisella +2 more
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Local pro-inflammatory cytokine and nitric oxide responses are elevated in patients with pterygium
International Journal of Immunopathology and Pharmacology, 2017 Pterygium is a common ocular surface disease observed in humans. Chronic ultraviolet (UV) exposure is extensively recognized as an aetiological factor in the pathogenesis of this disease.
S Zidi +7 more
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