Definition of a family of tissue-protective cytokines using functional cluster analysis: a proof-of-concept study [PDF]
, 2014 The discovery of the tissue-protective activities of erythropoietin (EPO) has underlined the importance of some cytokines in tissue-protection, repair, and remodeling.
Annenkov, Alexander +4 more
core +8 more sources
The importance of selected biomarkers in the clinical practice of breast cancer patients
Nowotwory, 2023 Breast cancer is considered the most commonly diagnosed tumors. Biomarkers used for the diagnosis and treatment of breast cancer are: tissue biomarkers (PR, ER, HER2, Ki-67) and serum biomarkers (CA-15-3, CA-125, CA-27-29, CEA, cytokeratins).
Agata Makówka, Beata Kotowicz
doaj +1 more source
Smoking in asthma is associated with elevated levels of corticosteroid resistant sputum cytokines—an exploratory study [PDF]
, 2013 <p>Background: Current cigarette smoking is associated with reduced acute responses to corticosteroids and worse clinical outcomes in stable chronic asthma. The mechanism by which current smoking promotes this altered behavior is currently unclear.
A McKay +40 more
core +11 more sources
Frontiers in Immunology, 2022 IL-1 plays a crucial role in triggering sterile inflammation following tissue injury. Although most studies associate IL-1 release by injured cells to the recruitment of neutrophils for tissue repair, the inflammatory cascade involves several molecular ...
Sevda Cordier-Dirikoc +11 more
doaj +1 more source
Engineering cytokines and cytokine circuits
Science, 2020 Learning to speak the secret language of immune cells could improve ...
Aileen W, Li, Wendell A, Lim
openaire +3 more sources
Antiviral and Immunomodulatory Properties of Antimicrobial Peptides Produced by Human Keratinocytes
Frontiers in Microbiology, 2020 Keratinocytes, the main cells of the epidermis, are the first site of replication as well as the first line of defense against many viruses such as arboviruses, enteroviruses, herpes viruses, human papillomaviruses, or vaccinia virus.
Céline Chessa +9 more
doaj +1 more source
Cytokine-Mediated Crosstalk Between Keratinocytes and T Cells in Atopic Dermatitis
Frontiers in Immunology, 2022 Atopic dermatitis (AD) is a chronic inflammatory skin disease characterized by barrier dysfunction, dysregulated immune response, and dysbiosis with increased Staphylococcus aureus colonization. Infiltration of various T helper cell subsets into lesional
Mélanie Humeau +2 more
doaj +1 more source
Cytokines of Birds: Conserved Functions [PDF]
, 2001 Targeted disruptions of the mouse genes for cytokines, cytokine receptors, or components of cytokine signaling cascades convincingly revealed the important roles of these molecules in immunologic processes. Cytokines are used at present as drugs to fight
Göbel, Thomas W. F. +4 more
core +1 more source
Specific features of human monocytes activation by monophosphoryl lipid A
Scientific Reports, 2018 We deciphered the mechanisms of production of pro- and anti-inflammatory cytokines by adherent human blood mononuclear cells (PBMC) activated by lipopolysaccharide (LPS) or monophosphoryl lipid A (MPLA).
Ryme Chentouh +2 more
doaj +1 more source
Suggestive evidence of a multi-cytokine resistin pathway in humans and its role on cardiovascular events in high-risk individuals [PDF]
, 2017 In cells and tissues resistin affects IL-1β, IL-6, IL-8, IL-12 and TNF-α expression, thus suggesting the existence of a multi-cytokine "resistin pathway".
Antonucci, Alessandra +8 more
core +1 more source