Results 11 to 20 of about 2,463,586 (344)
TLR2 senses the SARS-CoV-2 envelope protein to produce inflammatory cytokines
Nature Immunology, 2021 The innate immune response is critical for recognizing and controlling infections through the release of cytokines and chemokines. However, severe pathology during some infections, including SARS-CoV-2, is driven by hyperactive cytokine release, or a ...
Min Zheng +7 more
semanticscholar +1 more source
Cytokines: From Clinical Significance to Quantification
Advancement of science, 2021 Cytokines are critical mediators that oversee and regulate immune and inflammatory responses via complex networks and serve as biomarkers for many diseases.
Chao Liu +5 more
semanticscholar +1 more source
Cytokines and Chemokines Involved in Osteoarthritis Pathogenesis
International Journal of Molecular Sciences, 2021 Osteoarthritis is a common cause of disability worldwide. Although commonly referred to as a disease of the joint cartilage, osteoarthritis affects all joint tissues equally.
Vilim Molnar +18 more
semanticscholar +1 more source
The importance of selected biomarkers in the clinical practice of breast cancer patients
Nowotwory, 2023 Breast cancer is considered the most commonly diagnosed tumors. Biomarkers used for the diagnosis and treatment of breast cancer are: tissue biomarkers (PR, ER, HER2, Ki-67) and serum biomarkers (CA-15-3, CA-125, CA-27-29, CEA, cytokeratins).
Agata Makówka, Beata Kotowicz
doaj +1 more source
Frontiers in Immunology, 2022 IL-1 plays a crucial role in triggering sterile inflammation following tissue injury. Although most studies associate IL-1 release by injured cells to the recruitment of neutrophils for tissue repair, the inflammatory cascade involves several molecular ...
Sevda Cordier-Dirikoc +11 more
doaj +1 more source
Emerging Microbes and Infections, 2020 Since the outbreak of coronavirus disease 2019 (COVID-19) in Wuhan, China, it has rapidly spread across many other countries. While the majority of patients were considered mild, critically ill patients involving respiratory failure and multiple organ ...
Huan Han +13 more
semanticscholar +1 more source
Antiviral and Immunomodulatory Properties of Antimicrobial Peptides Produced by Human Keratinocytes
Frontiers in Microbiology, 2020 Keratinocytes, the main cells of the epidermis, are the first site of replication as well as the first line of defense against many viruses such as arboviruses, enteroviruses, herpes viruses, human papillomaviruses, or vaccinia virus.
Céline Chessa +9 more
doaj +1 more source
Cytokine-Mediated Crosstalk Between Keratinocytes and T Cells in Atopic Dermatitis
Frontiers in Immunology, 2022 Atopic dermatitis (AD) is a chronic inflammatory skin disease characterized by barrier dysfunction, dysregulated immune response, and dysbiosis with increased Staphylococcus aureus colonization. Infiltration of various T helper cell subsets into lesional
Mélanie Humeau +2 more
doaj +1 more source
Definition of a family of tissue-protective cytokines using functional cluster analysis: a proof-of-concept study [PDF]
, 2014 The discovery of the tissue-protective activities of erythropoietin (EPO) has underlined the importance of some cytokines in tissue-protection, repair, and remodeling.
Annenkov, Alexander +4 more
core +3 more sources
Amyloid beta and diabetic pathology cooperatively stimulate cytokine expression in an Alzheimer's mouse model [PDF]
, 2020 Background Diabetes is a risk factor for developing Alzheimer's disease (AD); however, the mechanism by which diabetes can promote AD pathology remains unknown.
Fernández Ponce, Cecilia Matilde +7 more
core +3 more sources