Results 11 to 20 of about 2,504,942 (386)

Cytokine storm and COVID-19: a chronicle of pro-inflammatory cytokines

Open Biology, 2020
Coronavirus disease 2019 (COVID-19) has swept the world, unlike any other pandemic in the last 50 years. Our understanding of the disease has evolved rapidly since the outbreak; disease prognosis is influenced mainly by multi-organ involvement.
A. Fara, Z. Mitrev, Rodney A. Rosalia, B. Assas   +3 more
semanticscholar   +2 more sources

Smoking in asthma is associated with elevated levels of corticosteroid resistant sputum cytokines—an exploratory study [PDF]

, 2013
<p>Background: Current cigarette smoking is associated with reduced acute responses to corticosteroids and worse clinical outcomes in stable chronic asthma. The mechanism by which current smoking promotes this altered behavior is currently unclear.
A McKay, A Sykes, B Pedersen, Carl de Wet, Charles McSharry, Christopher J. Weir, E Goleva, E Goleva, E Irusen, E Juniper, E Livingston, GJ Zijlstra, GW Chalmers, GW Chalmers, H Kerstjens, J Kam, J St-Laurent, JEM Tomlinson, M Althuis, M Broekema, M Spears, Marco Idzko, Mark Spears, MR Edwards, MR Miller, MR Stämpfli, NC Thomson, Neil C. Thomson, R Chaudhuri, R Chaudhuri, R Crapo, R Meijer, R Sher, Rekha Chaudhuri, S Holgate, SC Lazarus, SE Pedersen, SE Wenzel, WE Naugler, Z Qiu, Z Xing   +40 more
core   +16 more sources

Expression of SARS-CoV-2 Spike Protein Receptor Binding Domain on Recombinant B. subtilis on Spore Surface: A Potential COVID-19 Oral Vaccine Candidate

Vaccines, 2021
Various types of vaccines, such as mRNA, adenovirus, and inactivated virus by injection, have been developed to prevent SARS-CoV-2 infection. Although some of them have already been approved under the COVID-19 pandemic, various drawbacks, including ...
Johnny Chun-Chau Sung, Ying Liu, Kam-Chau Wu, Man-Chung Choi, Chloe Ho-Yi Ma, Jayman Lin, Emily Isabel Cheng He, David Yiu-Ming Leung, Eric Tung-Po Sze, Yusuf Khwaja Hamied, Dominic Man-Kit Lam, Keith Wai-Yeung Kwong   +11 more
doaj   +1 more source

Retraction: Sung et al. Expression of SARS-CoV-2 Spike Protein Receptor Binding Domain on Recombinant B. subtilis on Spore Surface: A Potential COVID-19 Oral Vaccine Candidate. Vaccines 2022, 10, 2

Vaccines, 2022
The journal retracts the article “Expression of SARS-CoV-2 Spike Protein Receptor Binding Domain on Recombinant B. subtilis on Spore Surface: A Potential COVID-19 Oral Vaccine Candidate” [...]
Johnny Chun-Chau Sung, Ying Liu, Kam-Chau Wu, Man-Chung Choi, Chloe Ho-Yi Ma, Jayman Lin, Emily Isabel Cheng He, David Yiu-Ming Leung, Eric Tung-Po Sze, Yusuf Khwaja Hamied, Dominic Man-Kit Lam, Keith Wai-Yeung Kwong   +11 more
doaj   +1 more source

The Antiviral Activities of Poly-ADP-Ribose Polymerases

Viruses, 2021
The poly-adenosine diphosphate (ADP)-ribose polymerases (PARPs) are responsible for ADP-ribosylation, a reversible post-translational modification involved in many cellular processes including DNA damage repair, chromatin remodeling, regulation of ...
Mathilde Malgras, Magali Garcia, Clément Jousselin, Charles Bodet, Nicolas Lévêque   +4 more
doaj   +1 more source

Oral Vaccines: A Better Future of Immunization

Vaccines, 2023
Oral vaccines are gaining more attention due to their ease of administration, lower invasiveness, generally greater safety, and lower cost than injectable vaccines. This review introduces certified oral vaccines for adenovirus, recombinant protein-based,
Keith Wai-Yeung Kwong, Ying Xin, Nelson Cheuk-Yin Lai, Johnny Chun-Chau Sung, Kam-Chau Wu, Yusuf Khwaja Hamied, Eric Tung-Po Sze, Dominic Man-Kit Lam   +7 more
doaj   +1 more source

Safety and Immunogenicity of Inactivated Bacillus subtilis Spores as a Heterologous Antibody Booster for COVID-19 Vaccines

Vaccines, 2022
The coronavirus diseases 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections have threatened the world for more than 2 years.
Johnny Chun-Chau Sung, Nelson Cheuk-Yin Lai, Kam-Chau Wu, Man-Chung Choi, Chloe Ho-Yi Ma, Jayman Lin, Cheong-Nang Kuok, Wai-Leng Leong, Weng-Kei Lam, Yusuf Khwaja Hamied, Dominic Man-Kit Lam, Eric Tung-Po Sze, Keith Wai-Yeung Kwong   +12 more
doaj   +1 more source

IL-17 and IL-22 are pivotal cytokines to delay wound healing of S. aureus and P. aeruginosa infected skin

Frontiers in Immunology, 2022
IntroductionAlthough the presence of pathogens in skin wounds is known to delay the wound healing process, the mechanisms underlying this delay remain poorly understood.
Jean-Claude Lecron, Jean-Claude Lecron, Sandrine Charreau, Sandrine Charreau, Jean-François Jégou, Nadjet Salhi, Isabelle Petit-Paris, Emmanuel Guignouard, Christophe Burucoa, Christophe Burucoa, Laure Favot-Laforge, Charles Bodet, Anne Barra, Anne Barra, Vincent Huguier, Vincent Huguier, Jiad Mcheik, Jiad Mcheik, Laure Dumoutier, Julien Garnier, François-Xavier Bernard, François-Xavier Bernard, Bernhard Ryffel, Franck Morel   +23 more
doaj   +1 more source

Phenol-soluble modulins α are major virulence factors of Staphylococcus aureus secretome promoting inflammatory response in human epidermis

Virulence, 2021
Staphylococcus aureus is a skin commensal microorganism commonly colonizing healthy humans. Nevertheless, S. aureus can also be responsible for cutaneous infections and contribute to flare-up of inflammatory skin diseases such as atopic dermatitis (AD ...
Alexia Damour, Brandon Robin, Luc Deroche, Lauranne Broutin, Nicolas Bellin, Julien Verdon, Gérard Lina, Franck Marie Leclère, Magali Garcia, Julie Cremniter, Nicolas Lévêque, Charles Bodet   +11 more
doaj   +1 more source

Dictionary of immune responses to cytokines at single-cell resolution

Nature, 2023
Cytokines mediate cell–cell communication in the immune system and represent important therapeutic targets1–3. A myriad of studies have highlighted their central role in immune function4–13, yet we lack a global view of the cellular responses of each ...
Ang Cui, Teddy Huang, Shuqiang Li, Aileen Ma, Jorge L. Pérez, C. Sander, Derin B. Keskin, Catherine J. Wu, E. Fraenkel, N. Hacohen   +9 more
semanticscholar   +1 more source