Results 11 to 20 of about 1,697,286 (361)

Characterisation of Antiviral Activity of Cathelicidins from Naked Mole Rat and Python bivittatus on Human Herpes Simplex Virus 1

open access: yesPharmaceuticals, 2021
Hg-CATH and Pb-CATH4 are cathelicidins from Heterocephalus glaber and Python bivittatus that have been previously identified as potent antibacterial peptides. However, their antiviral properties were not previously investigated.
Alexia Damour   +6 more
doaj   +1 more source

Dermal fibroblasts are the key sensors of aseptic skin inflammation through interleukin 1 release by lesioned keratinocytes

open access: yesFrontiers in Immunology, 2022
IL-1 plays a crucial role in triggering sterile inflammation following tissue injury. Although most studies associate IL-1 release by injured cells to the recruitment of neutrophils for tissue repair, the inflammatory cascade involves several molecular ...
Sevda Cordier-Dirikoc   +11 more
doaj   +1 more source

Smoking in asthma is associated with elevated levels of corticosteroid resistant sputum cytokines—an exploratory study [PDF]

open access: yes, 2013
<p>Background: Current cigarette smoking is associated with reduced acute responses to corticosteroids and worse clinical outcomes in stable chronic asthma. The mechanism by which current smoking promotes this altered behavior is currently unclear.
A McKay   +40 more
core   +10 more sources

Antiviral and Immunomodulatory Properties of Antimicrobial Peptides Produced by Human Keratinocytes

open access: yesFrontiers in Microbiology, 2020
Keratinocytes, the main cells of the epidermis, are the first site of replication as well as the first line of defense against many viruses such as arboviruses, enteroviruses, herpes viruses, human papillomaviruses, or vaccinia virus.
Céline Chessa   +9 more
doaj   +1 more source

Cytokine-Mediated Crosstalk Between Keratinocytes and T Cells in Atopic Dermatitis

open access: yesFrontiers in Immunology, 2022
Atopic dermatitis (AD) is a chronic inflammatory skin disease characterized by barrier dysfunction, dysregulated immune response, and dysbiosis with increased Staphylococcus aureus colonization. Infiltration of various T helper cell subsets into lesional
Mélanie Humeau   +2 more
doaj   +1 more source

Definition of a family of tissue-protective cytokines using functional cluster analysis: a proof-of-concept study [PDF]

open access: yes, 2014
The discovery of the tissue-protective activities of erythropoietin (EPO) has underlined the importance of some cytokines in tissue-protection, repair, and remodeling.
Annenkov, Alexander   +4 more
core   +3 more sources

IL-7-Adjuvanted Vaginal Vaccine Elicits Strong Mucosal Immune Responses in Non-Human Primates

open access: yesFrontiers in Immunology, 2021
Mucosal immune responses are crucial in protecting against pathogens entering through mucosal surfaces. However, due to poor T-cell responsiveness upon mucosal antigenic stimulation, mucosal immunity remains difficult to obtain through vaccines and ...
Sandrine Logerot   +9 more
doaj   +1 more source

Cytokines of Birds: Conserved Functions [PDF]

open access: yes, 2001
Targeted disruptions of the mouse genes for cytokines, cytokine receptors, or components of cytokine signaling cascades convincingly revealed the important roles of these molecules in immunologic processes. Cytokines are used at present as drugs to fight
Göbel, Thomas W. F.   +4 more
core   +1 more source

Cardiac oxidative stress and inflammatory cytokines response after myocardial infarction [PDF]

open access: yes, 2015
Oxidative stress in heart failure or during ischemia/reperfusion occurs as a result of the excessive generation or accumulation of free radicals or their oxidation products.
Cerretani D.   +6 more
core   +1 more source

Engineering cytokines and cytokine circuits

open access: yesScience, 2020
Learning to speak the secret language of immune cells could improve ...
Wendell A. Lim, Aileen W. Li
openaire   +4 more sources

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