Results 11 to 20 of about 1,697,286 (361)
Hg-CATH and Pb-CATH4 are cathelicidins from Heterocephalus glaber and Python bivittatus that have been previously identified as potent antibacterial peptides. However, their antiviral properties were not previously investigated.
Alexia Damour+6 more
doaj +1 more source
IL-1 plays a crucial role in triggering sterile inflammation following tissue injury. Although most studies associate IL-1 release by injured cells to the recruitment of neutrophils for tissue repair, the inflammatory cascade involves several molecular ...
Sevda Cordier-Dirikoc+11 more
doaj +1 more source
Smoking in asthma is associated with elevated levels of corticosteroid resistant sputum cytokines—an exploratory study [PDF]
<p>Background: Current cigarette smoking is associated with reduced acute responses to corticosteroids and worse clinical outcomes in stable chronic asthma. The mechanism by which current smoking promotes this altered behavior is currently unclear.
A McKay+40 more
core +10 more sources
Antiviral and Immunomodulatory Properties of Antimicrobial Peptides Produced by Human Keratinocytes
Keratinocytes, the main cells of the epidermis, are the first site of replication as well as the first line of defense against many viruses such as arboviruses, enteroviruses, herpes viruses, human papillomaviruses, or vaccinia virus.
Céline Chessa+9 more
doaj +1 more source
Cytokine-Mediated Crosstalk Between Keratinocytes and T Cells in Atopic Dermatitis
Atopic dermatitis (AD) is a chronic inflammatory skin disease characterized by barrier dysfunction, dysregulated immune response, and dysbiosis with increased Staphylococcus aureus colonization. Infiltration of various T helper cell subsets into lesional
Mélanie Humeau+2 more
doaj +1 more source
Definition of a family of tissue-protective cytokines using functional cluster analysis: a proof-of-concept study [PDF]
The discovery of the tissue-protective activities of erythropoietin (EPO) has underlined the importance of some cytokines in tissue-protection, repair, and remodeling.
Annenkov, Alexander+4 more
core +3 more sources
IL-7-Adjuvanted Vaginal Vaccine Elicits Strong Mucosal Immune Responses in Non-Human Primates
Mucosal immune responses are crucial in protecting against pathogens entering through mucosal surfaces. However, due to poor T-cell responsiveness upon mucosal antigenic stimulation, mucosal immunity remains difficult to obtain through vaccines and ...
Sandrine Logerot+9 more
doaj +1 more source
Cytokines of Birds: Conserved Functions [PDF]
Targeted disruptions of the mouse genes for cytokines, cytokine receptors, or components of cytokine signaling cascades convincingly revealed the important roles of these molecules in immunologic processes. Cytokines are used at present as drugs to fight
Göbel, Thomas W. F.+4 more
core +1 more source
Cardiac oxidative stress and inflammatory cytokines response after myocardial infarction [PDF]
Oxidative stress in heart failure or during ischemia/reperfusion occurs as a result of the excessive generation or accumulation of free radicals or their oxidation products.
Cerretani D.+6 more
core +1 more source
Engineering cytokines and cytokine circuits
Learning to speak the secret language of immune cells could improve ...
Wendell A. Lim, Aileen W. Li
openaire +4 more sources