Results 221 to 230 of about 1,145,654 (269)

Cytokines and anti-cytokines as therapeutics — An update

European Journal of Pharmacology, 2008
Cytokines which comprise of a family of proteins--interleukins, lymphokines, monokines, interferons, and chemokines, are important components of the immune system. They act in concert with specific cytokine inhibitors and soluble cytokine receptors to regulate the human immune response.
Vandana, Tayal, Bhupinder Singh, Kalra
openaire   +2 more sources

Cytokines in Cytokine Storm Syndrome

2019
As the eponymous mediators of the cytokine storm syndrome, cytokines are a pleomorphic and diverse set of soluble molecules that activate or suppress immune functions in a wide variety of ways. The relevant cytokines for each CSS are likely a result of differing combinations of environmental triggers and host susceptibilities.
openaire   +2 more sources

Cytokine and anti-cytokine therapy for asthma

Current Allergy and Asthma Reports, 2006
Cytokines play a critical role in the pathogenesis of asthma. Asthma resolution may depend on the correction of dysregulated cytokine expression, which is a characteristic feature of this chronic inflammatory disease. It is, therefore, not surprising that attempts have been made to either block cytokines present at elevated levels or to substitute ...
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Cytokines and Cytokine-Specific Therapy in Asthma

2012
Asthma is increasing in prevalence worldwide. It is characterized by typical symptoms and variable airway obstruction punctuated with episodes of worsening symptoms known as exacerbations. Underlying this clinical expression of disease is airway inflammation and remodeling.
Dhananjay, Desai, Christopher, Brightling   +1 more
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Cytokines, Cytokine Receptors and Cytokine Antibodies: Clinical Implications

1997
Cytokines are produced by almost any cell and function as important mediators of cell activation, differentiation and proliferation. These diffusibile glycoproteins appear to participate in the mediation of inflammatory as well as immune reactions, and some peptides may even influence tumor growth.
E. Berti, A. Cerri, D. Tomasini, R. Caputo   +3 more
openaire   +1 more source

Anti-inflammatory Cytokines and Cytokine Antagonists

Current Pharmaceutical Design, 2000
Cytokines are critical mediators of protective host responses, including defense against microbial invasion and tumorigenesis. However, the production of specific proinflammatory cytokines must be tightly regulated and compartmentalized to prevent the overzealous expression of these molecules that can culminate in unabated inflammation and tissue ...
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Cytokines and Biocompatibility

Blood Purification, 2008
Issues in biocompatibility have traditionally focused on the interaction of membranes or materials with the activation of complement, red blood cell destruction, clotting dysfunctions, and platelet activation. Other studies are concerned with the replacement fluid formulations and host responses.
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Cytokines

Current Opinion in Immunology, 2011
John, Hiscott, Carl, Ware
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Cytokines, cytokine receptors and cytokine antibodies

Melanoma Research, 1996
E. Berti, R. Caputo
openaire   +1 more source

Strategies to therapeutically modulate cytokine action

Nature Reviews Drug Discovery, 2023
Warren J Leonard, Jian-Xin Lin
exaly