Results 21 to 30 of about 2,504,942 (386)

Mechanism of co-operation of mutant IL-7Rα and mutant NRAS in acute lymphoblastic leukemia: role of MYC

open access: yesHaematologica, 2023
Acute lymphoblastic leukemia (ALL) is an aggressive leukemia which can be derived from either T-cell or B-cell precursors. With current treatments, the survival rate is high, but the treatments are highly toxic with severe side effects.
Hila Winer   +6 more
doaj   +1 more source

Characterisation of Antiviral Activity of Cathelicidins from Naked Mole Rat and Python bivittatus on Human Herpes Simplex Virus 1

open access: yesPharmaceuticals, 2021
Hg-CATH and Pb-CATH4 are cathelicidins from Heterocephalus glaber and Python bivittatus that have been previously identified as potent antibacterial peptides. However, their antiviral properties were not previously investigated.
Alexia Damour   +6 more
doaj   +1 more source

TLR2 senses the SARS-CoV-2 envelope protein to produce inflammatory cytokines

open access: yesNature Immunology, 2021
The innate immune response is critical for recognizing and controlling infections through the release of cytokines and chemokines. However, severe pathology during some infections, including SARS-CoV-2, is driven by hyperactive cytokine release, or a ...
Min Zheng   +7 more
semanticscholar   +1 more source

Assessment of novel antiviral filter using pseudo-type SARS-CoV-2 virus in fast air velocity vertical-type wind tunnel

open access: yesScientific Reports, 2023
Current evidence suggests that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can remain suspended spread in aerosols for longer period of time under poorly ventilated indoor setting.
Johnny Chun-Chau Sung   +6 more
doaj   +1 more source

Cytokines: From Clinical Significance to Quantification

open access: yesAdvancement of science, 2021
Cytokines are critical mediators that oversee and regulate immune and inflammatory responses via complex networks and serve as biomarkers for many diseases.
Chao Liu   +5 more
semanticscholar   +1 more source

The importance of selected biomarkers in the clinical practice of breast cancer patients

open access: yesNowotwory, 2023
Breast cancer is considered the most commonly diagnosed tumors. Biomarkers used for the diagnosis and treatment of breast cancer are: tissue biomarkers (PR, ER, HER2, Ki-67) and serum biomarkers (CA-15-3, CA-125, CA-27-29, CEA, cytokeratins).
Agata Makówka, Beata Kotowicz
doaj   +1 more source

Cytokines and Chemokines Involved in Osteoarthritis Pathogenesis

open access: yesInternational Journal of Molecular Sciences, 2021
Osteoarthritis is a common cause of disability worldwide. Although commonly referred to as a disease of the joint cartilage, osteoarthritis affects all joint tissues equally.
Vilim Molnar   +18 more
semanticscholar   +1 more source

Dermal fibroblasts are the key sensors of aseptic skin inflammation through interleukin 1 release by lesioned keratinocytes

open access: yesFrontiers in Immunology, 2022
IL-1 plays a crucial role in triggering sterile inflammation following tissue injury. Although most studies associate IL-1 release by injured cells to the recruitment of neutrophils for tissue repair, the inflammatory cascade involves several molecular ...
Sevda Cordier-Dirikoc   +11 more
doaj   +1 more source

Engineering cytokines and cytokine circuits

open access: yesScience, 2020
Learning to speak the secret language of immune cells could improve ...
Aileen W, Li, Wendell A, Lim
openaire   +3 more sources

Antiviral and Immunomodulatory Properties of Antimicrobial Peptides Produced by Human Keratinocytes

open access: yesFrontiers in Microbiology, 2020
Keratinocytes, the main cells of the epidermis, are the first site of replication as well as the first line of defense against many viruses such as arboviruses, enteroviruses, herpes viruses, human papillomaviruses, or vaccinia virus.
Céline Chessa   +9 more
doaj   +1 more source

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