Results 291 to 300 of about 1,823,964 (347)
Some of the next articles are maybe not open access.
Inhibitory cytokines and cytokine inhibitors
Neurology, 1995Cytokines such as interleukin-1 and tumor necrosis factor are involved in the triggering of the immune response, induction of acute inflammatory events, and transition to, or persistence of, chronic inflammation. The action of proinflammatory cytokines is regulated by their receptor expression, downregulation and shedding, by specific inhibitors, and ...
D, Burger, J M, Dayer
openaire +2 more sources
Cytokines and autoantibodies to cytokines
STEM CELLS, 1995Cytokines are essential components of our defense and repair systems but also potentially harmful mediators of infectious and immunoinflammatory reactions. Clinically important cytokines function systemically as pleiotropic hormones with overlapping effects on many cell types. All engage in a complex network of agonists and antagonists.
Bendtzen, Klaus +4 more
openaire +3 more sources
Cytokine-Cytokine Interactions in the Context of Cytokine Networking
American Journal of Respiratory Cell and Molecular Biology, 1992The start of the field of cytokine biology has been variously dated to 1951 with the discovery of nerve growth factor, 1954 with the discovery of interferon, the 1960s with the first description of "lymphokines," and 1966 with the discovery of "migration inhibitory factor" (1).
J A, Elias, R J, Zitnik
openaire +2 more sources
Cytokine, 2006
Genetic variation plays a significant role in the normal functioning of the immune system, and also in the interaction between many common drugs and cellular pathways. With a growing number of cytokine-based therapies now in mainstream clinical use, the prospect of targeting these agents to the individuals likely to benefit from them most is an ...
J R, Maxwell, A G, Wilson
openaire +2 more sources
Genetic variation plays a significant role in the normal functioning of the immune system, and also in the interaction between many common drugs and cellular pathways. With a growing number of cytokine-based therapies now in mainstream clinical use, the prospect of targeting these agents to the individuals likely to benefit from them most is an ...
J R, Maxwell, A G, Wilson
openaire +2 more sources
Current Opinion in Immunology, 1989
Cytokines manifest multiple biological activities in different target cells, and many cytokines are produced by a variety of cell types in response to different stimuli. Furthermore, the expression of a given cytokine gene is invariably influenced by other cytokines, forming a network of ‘cytokine cascades’.
openaire +2 more sources
Cytokines manifest multiple biological activities in different target cells, and many cytokines are produced by a variety of cell types in response to different stimuli. Furthermore, the expression of a given cytokine gene is invariably influenced by other cytokines, forming a network of ‘cytokine cascades’.
openaire +2 more sources
Inhaled cytokines and cytokine antagonists
Advanced Drug Delivery Reviews, 2006Cytokine and cytokine antagonist have provided novel and effective therapies for many human diseases. A number of approved cytokines including the interferons (alpha, beta and gamma), interleukin-2 (IL-2), granulocyte macrophage colony stimulating factor (GM-CSF) as well as novel cytokine antagonists have been administered by the pulmonary route for ...
openaire +2 more sources
2003
Cytokines are important mediators in inflammation, and play a key role in inflammation induced by Gram-negative bacteria. Cytokines are released into serum during different pathological conditions, such as meningococcal disease, and the cytokine levels in serum seem to correlate with fatal outcome of septic shock (1-3).
N B, Liabakk +4 more
openaire +2 more sources
Cytokines are important mediators in inflammation, and play a key role in inflammation induced by Gram-negative bacteria. Cytokines are released into serum during different pathological conditions, such as meningococcal disease, and the cytokine levels in serum seem to correlate with fatal outcome of septic shock (1-3).
N B, Liabakk +4 more
openaire +2 more sources
Cytokines in Cytokine Storm Syndrome
2019As the eponymous mediators of the cytokine storm syndrome, cytokines are a pleomorphic and diverse set of soluble molecules that activate or suppress immune functions in a wide variety of ways. The relevant cytokines for each CSS are likely a result of differing combinations of environmental triggers and host susceptibilities.
openaire +2 more sources
Chest, 2000
To review the concept of proinflammatory cytokines.Review of published literature.Academic (university hospital).Cytokines are regulators of host responses to infection, immune responses, inflammation, and trauma. Some cytokines act to make disease worse (proinflammatory), whereas others serve to reduce inflammation and promote healing (anti ...
openaire +2 more sources
To review the concept of proinflammatory cytokines.Review of published literature.Academic (university hospital).Cytokines are regulators of host responses to infection, immune responses, inflammation, and trauma. Some cytokines act to make disease worse (proinflammatory), whereas others serve to reduce inflammation and promote healing (anti ...
openaire +2 more sources
Current Opinion in Immunology, 1991
The molecular characterization of cytokine receptors has progressed rapidly over the past 5 years as a result of availability of radiolabeled cytokines, as well as the identification or creation of cell lines that express significant numbers of receptors at the cell surface.
openaire +2 more sources
The molecular characterization of cytokine receptors has progressed rapidly over the past 5 years as a result of availability of radiolabeled cytokines, as well as the identification or creation of cell lines that express significant numbers of receptors at the cell surface.
openaire +2 more sources