Results 311 to 320 of about 2,504,942 (386)

Modulation of IRAK4 as a therapeutic strategy against monosodium urate- and xanthine-induced inflammation in macrophages and HepG2 cells. [PDF]

Front Immunol
Umar S, Chang HT, Maienschein-Cline M, Ravindran S.   +3 more
europepmc   +1 more source

A Human Kidney Tubuloid Model of Repeated Cisplatin‐Induced Cellular Senescence and Fibrosis for Drug Screening

Advanced Healthcare Materials, EarlyView.
Replicating aging and senescence‐related pathophysiological responses in kidney organoids remains a significant challenge. Human adult renal tubular organoid, tubuloids, are successfully developed recapitulating cellular senescence that is the central pathophysiological mechanism of chronic kidney disease (CKD).
Yuki Nakao, Makiko Mori, Yuta Sekiguchi, Iori Morita, Ryota Shindoh, Shintaro Mandai, Tamami Fujiki, Hiroaki Kikuchi, Fumiaki Ando, Koichiro Susa, Takayasu Mori, Ayumi Suzuki, Yuji Nashimoto, Hirokazu Kaji, Yuma Waseda, Soichiro Yoshida, Yasuhisa Fujii, Eisei Sohara, Shinichi Uchida, Kensuke Miyake, Yutaro Mori   +20 more
wiley   +1 more source

Gut microbiota-mediated regulation of lipid metabolism by single herbal medicines: a review focused on cold/hot properties. [PDF]

Chin Med
Fang J, Wang S, Quan A, Zhu X, Li B, Jiang D.   +5 more
europepmc   +1 more source

Targeting Post‐Irradiation Thyroid Dysfunction: Electrospun Scaffolds As A Dual‐Action Approach for Antioxidant and Immune Modulation

Advanced Healthcare Materials, EarlyView.
Radiation‐induced hypothyroidism follows head and neck radiotherapy due to oxidative stress and inflammation. Electrospun polycaprolactone scaffolds containing adenosine have potential to modulate thyroid repair. Scaffolds enhance thyrocyte proliferation, antioxidant enzymes glutathione peroxidase and catalase, reduce senescence and apoptosis markers ...
Maria Heim, Ella‐Louise Handley, Daniel Grant, Lizi M. Hegarty, Elaine Emmerson, Anthony Callanan   +5 more
wiley   +1 more source

IL-1β, TNF-α, and IL-10 reduce cell viability and differentially alter biofilm structure and gene expression levels in <i>Staphylococcus aureus</i> USA 300. [PDF]

Front Immunol
Zavala-Hernández AN, Salto-Reyes C, Bravo-Patiño A, Baizabal-Aguirre VM, Valdez-Alarcón JJ.   +4 more
europepmc   +1 more source

Geometrically Tunable Scaffold‐Free Muscle Bioconstructs for Treating Volumetric Muscle Loss

Advanced Healthcare Materials, EarlyView.
Volumetric muscle loss is associated with traumatic muscle resulting in permanent functional impairment. Mold‐based, scaffold‐free, high‐density muscle tissue bioconstructs are developed in customizable geometric shapes and sizes. The transplanted rectangular solid‐shaped muscle bioconstructs improved muscle force recovery and tissue regeneration in ...
Bugra Ayan, Gaoxian Chen, Ishita Jain, Sha Chen, Gladys Chiang, Caroline Hu, Renato Reyes, Beu P. Oropeza, Ngan F. Huang   +8 more
wiley   +1 more source

New Clues to the Pathogenesis of Idiopathic Orbital Inflammation: Elevated IL-8 and MCP-1 in Tear Fluid. [PDF]

J Ophthalmol
Chen J, Xiao W, Ye H, Xu Z, Chen R, Yang H.   +5 more
europepmc   +1 more source

Xuebijing injection mitigates instant blood-mediated inflammatory reaction and enhances intrahepatic islet transplantation via target NF-κB pathway. [PDF]

Front Immunol
Zhan Y, Wang Y, Zhang B, Zhang Y, Liang R, Yang J, Liu T, Hu X, You T, Liu N, Chen Y, Liu Q, Jiang T, Liu Z, Cai X, Yang R, Qi Y, Sun P, Zou J, Ding X, Yin Z, Wang S.   +21 more
europepmc   +1 more source

Immune response in breastmilk of Black women to SARS-CoV-2 infection and vaccination against COVID-19. [PDF]

Front Nutr
Smith MO, Price J, Baker R, Neely H, Alfandari D, Bugg K, Sibeko L, Arcaro KF.   +7 more
europepmc   +1 more source

Neuroimmune circuits in respiratory pathophysiology: decoding molecular crosstalk for precision therapeutic targeting. [PDF]

Ann Med
Chen Q, Jia N, Liu J, Xu C, Shen Z, Shi S, Wang F, Wang Z.   +7 more
europepmc   +1 more source