Results 131 to 140 of about 54,277 (273)

Cytotoxic interaction of virus specific effector cells with virus infected targets of different cell type [PDF]

, 1976
Ertl, Hildegund, Koszinowski, Ulrich H.
core   +1 more source

The Paediatric BCG Vaccine Century: From Historical Success to Future Innovations

Acta Paediatrica, EarlyView.
ABSTRACT Aim The tuberculosis (TB) vaccine, Bacille‐Calmette‐Guérin (BCG), protects infants against severe forms of primary TB. Yet, it does not protect against pulmonary reactivation TB in adults. Methods A literature review was conducted between 1st January and 28th February 2025 using PubMed, Google Scholar and reports of the World Health ...
Stefan H. E. Kaufmann
wiley   +1 more source

Cell mediated cytotoxicity against Sendai virus infected cells [PDF]

, 1976
Bevan, Bhatnagar, Brunner, Gardner, Gardner, Gordon, Julius, Kedar, Kieling, Koszinowski, Koszinowski, Koszinowski, Lagrange, Lesley, Mcfarland, Pfizenmaier, Rehn, Reif, Schmitt-Verhulst, Shearer, Wagner, Zinkernagel   +21 more
core   +1 more source

Bleeding Disorders in Children With Genetic Diseases: A Narrative Review

Acta Paediatrica, EarlyView.
ABSTRACT Aim The lack of data on bleeding risk assessment in children with genetic diseases is concerning given their increased care needs and risk of haemorrhagic complications compared to the general population. Identification of haemostatic disorders is crucial for implementing preventive measures and mitigating bleeding risk.
Raphaelle Cagol, Mariam Sbeity Barakat, Marjolaine Willems, Tasnime Akbaraly, Biron‐Andreani Christine, Isabelle Diaz, Alexandre Theron   +6 more
wiley   +1 more source

Efficacy of immune checkpoint inhibitors in paediatric, adolescent and young adults with primary refractory or relapsed classical Hodgkin lymphoma: A national multicentre real‐world study

British Journal of Haematology, EarlyView.
Summary Classical Hodgkin lymphoma (cHL) is the most frequent lymphoma in children, adolescents and young adults (CAYA). Despite therapeutic advances, around 15% of patients relapse or have refractory (R/R) disease. Conventional salvage regimens remain effective but are associated with substantial long‐term toxicity. Immune checkpoint inhibitors (CPIs),
Marlène Pouthier, Nathalie Garnier, Amaury Leruste, Charlotte Rigaud, Catherine Curtillet, Stéphane Ducassou, Marilyne Poirée, Marie‐Emilie Dourthe, Cécile Pochon, Marie‐Laure Couec, Jacinthe Bonneau‐Lagacherie, Françoise Montravers, Sabah Boudjemaa, Bénédicte Jonca, Stéphanie Haouy, Thierry Leblanc, Judith Landman Parker, Mathieu Simonin   +17 more
wiley   +1 more source

AllergoOncology in Review: Harnessing Allergy in the Field of Oncology to Improve Patient Outcomes

Clinical &Experimental Allergy, EarlyView.
ABSTRACT The AllergoOncology field brings together the study of allergic and cancer immune responses, having evolved from early epidemiological studies that reported inverse associations between allergies, IgE and cancer risk. Insights from studying allergic inflammation are revealing previously unappreciated immune mechanisms that confer protective ...
Jakub Zydron, Anishaa Balaji, Jitesh Chauhan, Jack Alder, Xinyi Chen, Anna M. F. Wiegman, Aurelie Poli, Joanna Jacków‐Malinowska, Jack Cheeseman, Daniel I. R. Spencer, James McDonnell, James Spicer, Alexandra J. McCraw, Sophia N. Karagiannis   +13 more
wiley   +1 more source

Epicutaneous and Drug Provocation Testing in Severe Cutaneous Adverse Reactions: A 20‐Year Single‐Centre Experience

Contact Dermatitis, EarlyView.
This study provides reassuring evidence in favour of early skin testing in patients with SCARs, argues against the necessity of a 6‐month delay, and underscores the pivotal role of oral provocation tests in the safe reintroduction of essential therapies. ABSTRACT Background Identifying and discontinuing the offending drug(s) in severe cutaneous adverse
Zohra Chadli, Khadija Mansour, Ghada Jaouahdou, Manel Ben Belgacem, Yosra Soua, Nadia Ben Fredj, Jameleddine Zili, Haifa Ben Romdhane, Karim Aouam   +8 more
wiley   +1 more source

Hepatocarcinoma with tumor thrombus occupying the right atrium and portal vein in a patient with hereditary hemochromatosis and liver cirrhosis [PDF]

, 2018
We present the case of a 46-year old patient with Child-Pugh class C cirrhosis with MEDL-Score 16, and hepatocellular carcinoma invading the inferior vena cava and the right atrium.
Breaban, Iulia, Cozma, Angela, Fabian, Ovidiu, Mihailov, Anca, Muresan, Flaviu, Negrean, Vasile, Orasan, Olga Hilda, Sampelean, Dorel, Secara, Sorina Cezara, Stefan, Andreea Maria, Tarmure Sarlea, Simina, Urian, Laura   +11 more
core   +1 more source

Immune non‐response despite effective antiretroviral therapy in people living with HIV: A review of potential mechanisms, biomarkers and therapeutic approaches

HIV Medicine, EarlyView.
Abstract Introduction A proportion of people living with HIV (PLWH) fail to restore their CD4 count or their CD4/CD8 ratio despite effective antiretroviral therapy (ART). PLWH with immune non‐response (INR) are at a higher risk of both AIDS and non‐AIDS events. The underlying mechanisms of INR remain unclear.
Charlotte Silvestre, Antoine Gross, Alain Makinson   +2 more
wiley   +1 more source

Auto‐inducible expression of chimeric antigen receptor T cells using the NR4A1 promoter

Immunology &Cell Biology, EarlyView.
The NR4A1 promoter is a compact auto‐inducible promoter to drive CAR expression in T cells. Compared with EF1α, or existing synthetic antigen‐inducible promoters, NR4A1 is more compact and ensures that resting CAR T cells express reduced baseline CAR. NR4A1 allows rapid induction upon antigen encounter with reduced T‐cell exhaustion.
Samuel WJ Smith‐Bell, Joshua C Halpin, Phillip K Darcy, Thiloma Liyanage, Lachlan J Dobson, Alexander D McLellan   +5 more
wiley   +1 more source