Results 141 to 150 of about 44,623 (260)

Treatment in adult patients with acute myeloid leukemias with hyperleukocytosis at disease onset

Терапевтический архив, 2015
Aim. To evaluate the efficiency of the treatment policy for patients with acute myeloid leukemia (AML) and hyperleukocytosis (HL), which is aimed at preventing rapid hypercytolysis and massive tumor lysis (cytolysis) syndrome and/or at reducing the ...
V V Troitskaya, E N Parovichnikova, A N Sokolov, A V Kokhno, L A Kuzmina, D S Badmazhapova, Z T Fidarova, O A Gavrilina, A A Sidorova, G M Galstyan, S A Keselman, T V Gaponova, V S Galuzyak, S K Kravchenko, E O Gribanova, V G Savchenko   +15 more
doaj  

B‐Cell Follicles in the Secondary Lymphatic Tissues Act as a Critical Microanatomical Niche for Sustained Viral Replication, Virus‐Host Interaction and Damage During Chronic SIV Infection of Rhesus Macaques

Journal of Medical Virology, Volume 98, Issue 11, November 2026.
ABSTRACT Most people living with HIV‐1 (HIV) are diagnosed during the chronic stage of infection, at which point viral setpoint has been established and a substantial immunopathologic damage in the secondary lymphatic tissues (LTs) has been induced. To better characterize virus‐host interaction and immunopathologic damage in LTs, we investigated viral ...
Yilun Cheng, Miaoyun Zhao, Jackson Chen, Subhra Mandal, Mark G. Lewis, Qingsheng Li   +5 more
wiley   +1 more source

Cytolysis and piecemeal degranulation as distinct modes of activation of airway mucosal eosinophils [Elektronisk resurs]

, 1998
BACKGROUND: Cytotoxic eosinophil granule proteins are considered important in the pathogenesis of inflammatory airway diseases, including asthma, rhinitis, and polyposis.
Erjefält, Jonas,, Persson, G A, Korsgren, M, Andersson, M, Jeffery, P K, Greiff, Lennart,, Gizycki, M, Lund University.   +7 more
core  

Biological activities and bioactive constituents of Flammulina velutipes: An updated systematic review

Journal of the Science of Food and Agriculture, Volume 106, Issue 14, Page 8298-8314, November 2026.
Abstract Flammulina velutipes (enokitake) is an edible mushroom recognized for both its nutritional and medicinal properties. It exhibits a broad spectrum of biological activities, including antioxidant, anti‐inflammatory, antitumor, immunomodulatory, and gut microbiota‐regulating effects.
Rıdvan Özgen, Didem Şöhretoğlu, Ayşe Kuruüzüm‐Uz   +2 more
wiley   +1 more source

Impact of variety and environmental factors on proteolytic quality parameters of selected malting barley varieties

Journal of the Science of Food and Agriculture, Volume 106, Issue 14, Page 8628-8638, November 2026.
Abstract BACKGROUND Barley (Hordeum vulgare) is a major cereal crop, essential for global food processing and brewing. Malting barley represents less than one‐fifth of global barley output due to strict quality requirements, such as total protein content, enzymatic activity, and kernel homogeneity, which directly influence malting performance and ...
Shari Piro, Martina Gastl, Michael Féchir   +2 more
wiley   +1 more source

Cytolysis and piecemeal degranulation as distinct modes of activation of airway mucosal eosinophils

, 1998
BACKGROUND: Cytotoxic eosinophil granule proteins are considered important in the pathogenesis of inflammatory airway diseases, including asthma, rhinitis, and polyposis.
Persson, G A, Korsgren, M, Erjefält, Jonas, Andersson, M, Jeffery, P K, Greiff, Lennart, Gizycki, M   +6 more
core  

Therapeutic and Prophylactic Agents for Viral Diseases: Current Status, Challenges, and Future Prospects

MedComm, Volume 7, Issue 11, November 2026.
This review summarizes current therapeutic and prophylactic strategies for global viral diseases, including vaccines, PrEP, direct‐acting antivirals, and emerging modalities such as CRISPR and siRNA. It highlights their clinical impact, ongoing challenges, and future priorities toward broader protection, improved delivery, and more effective antiviral ...
Sawar Khan, Ayesha Nisar, Xiaoxu Li, Hao Yu, Abdul Qadeer, Sardar Azhar Mehmood, Imane Lamraoui, Sijie Liu, Lipeng Zhu, Xu Deng, Bo Kong, Kejun Zhong, Zanxian Xia   +12 more
wiley   +1 more source

Exosomes in Cancer: The Biology, Function, Diagnosis, and Therapy

MedComm, Volume 7, Issue 11, November 2026.
Tumor‐derived exosomes and nonmembranous extracellular nanoparticles (exomeres/supermeres) constitute a heterogeneous communication network that drives cancer progression. By shuttling functional biomolecules across tissue‐specific barriers, these nanoparticles orchestrate local microenvironmental remodeling, immune suppression, premetastatic niche ...
Jun Wu, Lei Wu, Kang Yang, Kang Xie, Tao Lu, Tiangxiang Huang, Dengfeng Wan, Tao Song, Longbo Zhang   +8 more
wiley   +1 more source

Impact of pH and <i>Mycoplasma hominis</i> endosymbiosis on <i>Trichomonas vaginalis</i> pathogenesis. [PDF]

Proc Natl Acad Sci U S A
Elikaee S, Mukherjee SK, Johnson PJ.
europepmc   +1 more source

Adipose‐Derived Mesenchymal Stem Cells: Isolation, Origin, Phenotype Applications, and Challenges

MedComm, Volume 7, Issue 11, November 2026.
Bridging basic biology to clinical translation, this review systematically explores the in vivo origins and evolving isolation techniques of AD‐MSCs. We dissect their diverse phenotype applications orchestrated by immunometabolic reprogramming, mitochondrial transfer, and extracellular vesicles.
Ziyang Liu, Guangming Tu, Chao Wang, Hongyan Zhao, Ziyi Wu, Wei Li, Li Chen, Bailin Niu   +7 more
wiley   +1 more source