Results 161 to 170 of about 54,277 (273)

Spatially Resolved Multiomics Reveals Metabolic Remodeling and Autophagy Activation in Adamantinomatous Craniopharyngiomas

open access: yesAdvanced Science, Volume 13, Issue 17, 23 March 2026.
Multiomics integration analysis reveals the “cystic fluid–tumor cell” metabolic coupling that mediates active choline/ethanolamine uptake of tumor cells from cystic fluid and PC/PE synthesis pathways reprogramming that mediating autophagy pathway activation within ACP. ABSTRACT Adamantinomatous craniopharyngioma (ACP), a benign yet highly recurrent and
Dongting Chen   +9 more
wiley   +1 more source

CRISPR screens identify PRMT7 as a therapeutic target to enhance T cell-mediated killing in breast cancer. [PDF]

open access: yesNPJ Breast Cancer
Shi W   +16 more
europepmc   +1 more source

Expression and immmunogenicity of HLA-B27 in high-transfection recipient P815: [PDF]

open access: yes, 1989
Kuon, W.   +4 more
core   +1 more source

Cytokine‐Engineered Chimeric Antigen Receptor‐T Cell Therapy: How to Balance the Efficacy and Toxicity

open access: yesAdvanced Science, Volume 13, Issue 14, 9 March 2026.
Cytokine‐engineered CAR‐T cells represent a promising immunotherapy against malignancies due to direct tumor killing and potent immunity response. However, significant toxicities, including CRS and ICANS, have restricted clinical applications. How to keep the risk‐benefit balance of the advanced therapy is of great importance for maximizing the benefit
Xinru Zhang   +7 more
wiley   +1 more source

Triple autoimmune overlap syndrome of the liver: a rare case of concomitant PBC, PSC, and AIH. [PDF]

open access: yesFuture Sci OA
Hassen H   +10 more
europepmc   +1 more source

Genetic Alterations Involved in Immune Escape Mechanisms of Circulating Tumour Cells in Colorectal Carcinogenesis

open access: yesCancer Medicine, Volume 15, Issue 3, March 2026.
ABSTRACT In colorectal cancer (CRC), circulating tumour cells (CTCs) employ genetic alterations to dodge the body's immune system. These alterations occur in specific “driver” genes, including KRAS, BRAF, p53, MYC, APC and PTEN. Changes in these genes can control how the tumour interacts with the immune system and influence the expression of immune ...
Sharmin Aktar   +5 more
wiley   +1 more source

Challenges in Diagnosing and Managing Hepatitis E in Transplant Recipients: A Case Report. [PDF]

open access: yesCase Rep Transplant
Martins AC   +5 more
europepmc   +1 more source

Lack of De‐Intensification Models for Female Head and Neck Cancer Patients With Favorable Prognosis

open access: yesCancer Medicine, Volume 15, Issue 3, March 2026.
ABSTRACT Purpose The prognostic relevance of gender in head and neck cancer is often neglected. In contrast, the more favorable prognosis of human papillomavirus (HPV)‐associated oropharyngeal squamous cell carcinoma (OPSCC) is well recognized, and de‐escalation strategies are increasingly being tested in clinical trials.
J. M. Vahl   +7 more
wiley   +1 more source

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