Results 171 to 180 of about 54,277 (273)

Acute Lupus Pneumonitis: An Uncommon Initial Presentation of Systemic Lupus Erythematosus—A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 3, March 2026.
ABSTRACT Acute lupus pneumonitis is a rare but potentially life‐threatening pulmonary manifestation of systemic lupus erythematosus, often presenting with nonspecific respiratory symptoms. We report a case of a 48‐year‐old female who presented with fever, dyspnea, and pleuritic chest pain.
Raj Adhikari, Prabin Khatri, Zainab Rauf
wiley   +1 more source

A Link Between Allergy and Hematological Malignancies? Focus on Possible Mechanisms and the Potential Role of Biological Therapies

open access: yesClinical and Translational Allergy, Volume 16, Issue 3, March 2026.
ABSTRACT Immune dysregulation has been widely recognized in the international literature as an underlying condition for hematological malignancies and allergic disorders. This commonality has led researchers to study the potential association, positive or negative, between blood cancers and allergy, but the results remain unclear.
Stefania Isola   +5 more
wiley   +1 more source

The multifaceted roles of the ACSL family in cancer: Metabolic reprogramming, ferroptosis regulation and tumour immune microenvironment remodelling

open access: yesClinical and Translational Medicine, Volume 16, Issue 3, March 2026.
The acyl‐CoA synthetase long‐chain (ACSL) family consists of five members, which exhibit a synergistic effect in promoting tumour lipid metabolism for energy supply. Specifically, ACSL3 and ACSL4 have antagonistic effects on the mechanisms related to ferroptosis in tumour cells.
Haocai Li   +6 more
wiley   +1 more source

UMG1 Defines a Targetable Subset of T‐Cell Lymphomas and Enables Precision Immunotherapy With a First‐in‐Class CD3ε Bispecific Engager

open access: yesHematological Oncology, Volume 44, Issue 2, March 2026.
ABSTRACT T‐cell lymphomas (TCLs) account for a relatively small fraction of lymphoid malignancies and are characterized by highly aggressive course often refractory to current available therapies. We previously reported potent in vitro and in vivo antitumor activity of a Bispecific T‐Cell Engager (UMG1/CD3ε‐BTCE) directed against UMG1, a unique CD43 ...
Daniele Caracciolo   +19 more
wiley   +1 more source

Cluster of Severe Arginase 1 Deficiency in the Comoros: Clinical, Neuroimaging, and Molecular Features in 17 Patients From Mayotte Compared With 10 From Paris

open access: yesJournal of Inherited Metabolic Disease, Volume 49, Issue 2, March 2026.
ABSTRACT Arginase 1 deficiency (ARG1D) is the least common urea cycle disorder. Neonatal onset is rarely described, and hyperammonemic coma is less common in patients with ARG1D compared to other urea cycle disorders. In recent years, we diagnosed a high number of ARG1D patients in Mayotte, an insular (Comoro Islands) department of France.
Aurélie De Bruyne   +16 more
wiley   +1 more source

Expert‐Designed Fact Sheets and AI‐Based Analysis of Patient Symptoms to Combat Diagnostic Delays in Inherited Metabolic Diseases

open access: yesJournal of Inherited Metabolic Disease, Volume 49, Issue 2, March 2026.
ABSTRACT The importance of early diagnosis of inherited metabolic diseases (IMDs) is well known, as it allows early intervention to prevent or reduce complications and improve prognosis, since many of these disorders are treatable. However, diagnosis can still be delayed, and many patients remain undiagnosed. Reducing diagnosis delays is a primary goal
Aline Cano   +108 more
wiley   +1 more source

Tumor-intrinsic interferon signaling drives pancreatic cancer resistance to tumor mucin1-targeted CAR T cell therapy. [PDF]

open access: yesFront Immunol
Zhou R   +6 more
europepmc   +1 more source

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