Results 21 to 30 of about 299,119 (223)
Post-LECA Origin and Diversification of an Axonemal Outer Arm Dynein Motor. [PDF]
Cytoskeleton (Hoboken)ABSTRACT Dyneins were present in the last eukaryotic common ancestor (LECA) and play key roles in eukaryotic biology. Axonemal dyneins form the inner and outer arms that power ciliary beating, and it has long been recognized that outer arms in some organisms contain two different heavy chain motors, whereas those from other species contain a third unit
King SM.
europepmc +2 more sources
Single-molecule fluorescence and in vivo optical traps: how multiple dyneins and kinesins interact.
Chemical Reviews, 2014 Benjamin H. Blehm, P. Selvin
semanticscholar +3 more sources
Ciliary Dyneins and Dynein Related Ciliopathies
Cells, 2021 Although ubiquitously present, the relevance of cilia for vertebrate development and health has long been underrated. However, the aberration or dysfunction of ciliary structures or components results in a large heterogeneous group of disorders in ...
D. Antony, H. Brunner, M. Schmidts
semanticscholar +1 more source
Dyneins Have Run Their Course in Plant Lineage
Traffic, 2001 Carolyn J. Lawrence-Dill +3 more
semanticscholar +3 more sources
Cytoplasmic dynein-2 at a glance [PDF]
Journal of Cell Science, 2020 ABSTRACT Cytoplasmic dynein-2 is a motor protein complex that drives the movement of cargoes along microtubules within cilia, facilitating the assembly of these organelles on the surface of nearly all mammalian cells. Dynein-2 is crucial for ciliary function, as evidenced by deleterious mutations in patients with skeletal abnormalities ...
Laura Vuolo +4 more
openaire +4 more sources
Cytoplasmic dynein and early endosome transport [PDF]
Cellular and Molecular Life Sciences, 2015 Microtubule-based distribution of organelles/vesicles is crucial for the function of many types of eukaryotic cells and the molecular motor cytoplasmic dynein is required for transporting a variety of cellular cargos toward the microtubule minus ends. Early endosomes represent a major cargo of dynein in filamentous fungi, and dynein regulators such as ...
Xiang, X +5 more
openaire +4 more sources
Spatio-temporal regulation of nuclear division by Aurora B kinase Ipl1 in Cryptococcus neoformans. [PDF]
PLoS Genetics, 2019 The nuclear division takes place in the daughter cell in the basidiomycetous budding yeast Cryptococcus neoformans. Unclustered kinetochores gradually cluster and the nucleus moves to the daughter bud as cells enter mitosis.
Neha Varshney +6 more
doaj +1 more source
Activation and Regulation of Cytoplasmic Dynein
Trends in Biochemical Sciences, 2020 Cytoplasmic dynein is an AAA+ motor that drives the transport of many intracellular cargoes towards the minus end of microtubules (MTs). Previous in vitro studies characterized isolated dynein as an exceptionally weak motor that moves slowly and diffuses on an MT. Recent studies altered this view by demonstrating that dynein remains in an autoinhibited
John T. Canty, Ahmet Yildiz
openaire +5 more sources
eLife, 2018 Construction of motile cilia/flagella requires cytoplasmic preassembly of axonemal dyneins before transport into cilia. Axonemal dyneins have various subtypes, but the roles of each dynein subtype and their assembly processes remain elusive in ...
Hiroshi Yamaguchi +3 more
doaj +1 more source
Nucleotide specificity of the enzymatic and motile activities of dynein, kinesin, and heavy meromyosin. [PDF]
, 1991 The substrate specificities of dynein, kinesin, and myosin substrate turnover activity and cytoskeletal filament-driven translocation were examined using 15 ATP analogues.
Furusawa, K +6 more
core +2 more sources