Results 41 to 50 of about 299,119 (223)

Homolog pairing during meiosis : dyneins on the move [PDF]

open access: yes, 2010
Meiosis is a specialized form of cell division that generates haploid gametes from diploid cells. This is achieved by having 1 round of DNA replication followed by 2 rounds of nuclear division.
Arumugam, Prakash
core   +1 more source

Cryo-electron tomography reveals that dynactin recruits a team of dyneins for processive motility

open access: yesNature Structural & Molecular Biology, 2017
Cytoplasmic dynein is a protein complex that transports molecular cargo along microtubules (MTs), playing a key role in the intracellular trafficking network.
D. Grotjahn   +5 more
semanticscholar   +1 more source

Discrete PIH proteins function in the cytoplasmic preassembly of different subsets of axonemal dyneins

open access: yesJournal of Cell Biology, 2010
Mot48, a PIH domain protein, assembles and stabilizes inner arm dynein complexes in the cytoplasm before they are transported into cilia.
Ryosuke Yamamoto, M. Hirono, R. Kamiya
semanticscholar   +1 more source

Parasite motility is critical for virulence of African trypanosomes. [PDF]

open access: yes, 2018
African trypanosomes, Trypanosoma brucei spp., are lethal pathogens that cause substantial human suffering and limit economic development in some of the world's most impoverished regions.
Geng, Quanjie   +6 more
core   +1 more source

FAP57/WDR65 targets assembly of a subset of inner arm dyneins and connects to regulatory hubs in cilia

open access: yesbioRxiv, 2019
Ciliary motility depends on both the precise spatial organization of multiple dynein motors within the 96 nm axonemal repeat, and highly coordinated interactions between different dyneins and regulatory complexes located at the base of the radial spokes.
Jianfeng Lin   +12 more
semanticscholar   +1 more source

Unbinding Force of Cytoplasmic Dynein [PDF]

open access: yesBiophysical Journal, 2011
Dynein is a molecular motor that moves toward the minus-end of microtubules using the chemical energy of ATP hydrolysis. Cytoplasmic dynein play roles in positioning the Golgi complex and other organelles in cells, movement of chromosomes, and positioning the mitotic spindles during mitosis.
Kambara, Taketoshi   +2 more
openaire   +1 more source

Lissencephaly-1 is a context-dependent regulator of the human dynein complex

open access: yeseLife, 2017
The cytoplasmic dynein-1 (dynein) motor plays a central role in microtubule organisation and cargo transport. These functions are spatially regulated by association of dynein and its accessory complex dynactin with dynamic microtubule plus ends. Here, we
Janina Baumbach   +6 more
doaj   +1 more source

Spatial Organization of the Cytoskeleton enhances Cargo Delivery to Specific Target Areas on the Plasma Membrane of Spherical Cells [PDF]

open access: yes, 2016
Intracellular transport is vital for the proper functioning and survival of a cell. Cargo (proteins, vesicles, organelles, etc.) is transferred from its place of creation to its target locations via molecular motor assisted transport along cytoskeletal ...
Hafner, Anne E., Rieger, Heiko
core   +2 more sources

Directional instability of microtubule transport in the presence of kinesin and dynein, two opposite polarity motor proteins. [PDF]

open access: yes, 1992
Kinesin and dynein are motor proteins that move in opposite directions along microtubules. In this study, we examine the consequences of having kinesin and dynein (ciliary outer arm or cytoplasmic) bound to glass surfaces interacting with the same ...
Brown, D, Malik, F, Vale, RD
core   +2 more sources

ZMYND10 functions in a chaperone relay during axonemal dynein assembly [PDF]

open access: yes, 2018
Molecular chaperones promote the folding and macromolecular assembly of a diverse set of ‘client’ proteins. How ubiquitous chaperone machineries direct their activities towards specific sets of substrates is unclear.
Dodd Daniel O   +17 more
core   +8 more sources

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