Results 51 to 60 of about 299,119 (223)

Brain Cytoplasmic and Flagellar Outer Arm Dyneins Share a Highly Conserved Mr 8,000 Light Chain*

Journal of Biological Chemistry, 1996
Sequence comparisons with the Mr 8,000 light chain from Chlamydomonas outer arm dynein revealed the presence of highly conserved homologues (up to 90% identity) in the expressed sequence tag data base (King, S. M. & Patel-King, R. S. (1995a) J.
S. King, Elisa Barbarese¶i, J. Dillman, R. Patel-King, John H. Carson‡i, K. Pfister   +5 more
semanticscholar   +1 more source

HEATR2 plays a conserved role in assembly of the ciliary motile apparatus.

PLoS Genetics, 2014
Cilia are highly conserved microtubule-based structures that perform a variety of sensory and motility functions during development and adult homeostasis.
Christine P Diggle, Daniel J Moore, Girish Mali, Petra zur Lage, Aouatef Ait-Lounis, Miriam Schmidts, Amelia Shoemark, Amaya Garcia Munoz, Mihail R Halachev, Philippe Gautier, Patricia L Yeyati, David T Bonthron, Ian M Carr, Bruce Hayward, Alexander F Markham, Jilly E Hope, Alex von Kriegsheim, Hannah M Mitchison, Ian J Jackson, Bénédicte Durand, Walter Reith, Eamonn Sheridan, Andrew P Jarman, Pleasantine Mill   +23 more
doaj   +1 more source

Model for the unidirectional motion of a dynein molecule

, 2008
Cytoplasmic dyneins transport cellular organelles by moving on a microtubule filament. It has been found recently that depending on the applied force and the concentration of the adenosine triphosphate (ATP) molecules, dynein's step size varies. Based on
B. Alberts, M. Schnitzer, S. M. King, Sutapa Mukherji, T. Shima   +4 more
core   +1 more source

Dynein structure and power stroke [PDF]

, 2003
Dynein ATPases are microtubule motors that are critical to diverse processes such as vesicle transport and the beating of sperm tails; however, their mechanism of force generation is unknown.
A Elliot, AF Neuwald, CK Omoto, DJ Asai, DM Woolley, G Mocz, G Mocz, GG Vernon, H Sakakibara, IR Gibbons, IR Gibbons, IR Gibbons, IR Gibbons, IR Gibbons, J Fan, J Frank, K Ogawa, K Shiroguchi, KA Johnson, LM DiBella, M Okuno, M Samsó, MA Gee, MA Gee, ML Walker, MP Koonce, MP Koonce, RB Vallee, RD Vale, RD Vale, RD Vale, S Karki, SA Burgess, SA Burgess, SM King, SM King, T Yagi, UW Goodenough, UW Goodenough, UW Goodenough, UW Goodenough   +40 more
core   +1 more source

Cytoplasmic dynein binding, run length, and velocity are guided by long-range electrostatic interactions

Scientific Reports, 2016
Dyneins are important molecular motors involved in many essential biological processes, including cargo transport along microtubules, mitosis, and in cilia.
Lin Li, Joshua D Alper, E. Alexov
semanticscholar   +1 more source

Cytoplasmic Dynein Mediates Adenovirus Binding to Microtubules [PDF]

Journal of Virology, 2004
ABSTRACT During infection, adenovirus (Ad) capsids undergo microtubule-dependent retrograde transport as part of a program of vectorial transport of the viral genome to the nucleus. The microtubule-associated molecular motor, cytoplasmic dynein, has been implicated in the retrograde movement of Ad. We hypothesized
Samir A, Kelkar, K Kevin, Pfister, Ronald G, Crystal, Philip L, Leopold   +3 more
openaire   +2 more sources

The preprophase band-associated kinesin-14 OsKCH2 is a processive minus-end-directed microtubule motor. [PDF]

, 2018
In animals and fungi, cytoplasmic dynein is a processive minus-end-directed motor that plays dominant roles in various intracellular processes. In contrast, land plants lack cytoplasmic dynein but contain many minus-end-directed kinesin-14s.
Bowen, Joel, Gicking, Allison M, Guo, Lijun, Lee, Yuh-Ru Julie, Liu, Bo, Qiu, Weihong, Tseng, Kuo-Fu, Wang, Pan   +7 more
core   +3 more sources

Control of cytoplasmic dynein force production and processivity by its C-terminal domain

Nature Communications, 2015
Cytoplasmic dynein is a microtubule motor involved in cargo transport, nuclear migration and cell division. Despite structural conservation of the dynein motor domain from yeast to higher eukaryotes, the extensively studied S.
M. Nicholas, P. Höök, Sibylle Brenner, Caitlin L. Wynne, R. Vallee, A. Gennerich   +5 more
semanticscholar   +1 more source

Cargo adaptors regulate stepping and force generation of mammalian dynein-dynactin. [PDF]

, 2019
Cytoplasmic dynein is an ATP-driven motor that transports intracellular cargos along microtubules. Dynein adopts an inactive conformation when not attached to a cargo, and motility is activated when dynein assembles with dynactin and a cargo adaptor.
Blanchard, Scott C, Canty, John T, Elshenawy, Mohamed M, Ferro, Luke S, Oster, Liya, Yildiz, Ahmet, Zhou, Zhou   +6 more
core  

From aggressive driving to molecular motor traffic [PDF]

, 2006
Motivated by recent experimental results for the step sizes of dynein motor proteins, we develope a cellular automata model for intra-cellular traffic of dynein motors incorporating special features of the hindrance-dependent step size of the individual ...
Chowdhury, Debashish, Kunwar, Ambarish, Schadschneider, Andreas   +2 more
core   +4 more sources