Liquid demixing in elastic networks: cavitation, permeation, or size selection? [PDF]
Demixing of multicomponent biomolecular systems via liquid-liquid phase separation (LLPS) has emerged as a potentially unifying mechanism governing the formation of several membrane-less intracellular organelles ("condensates"), both in the cytoplasm (e.g., stress granules) and in the nucleoplasm (e.g., nucleoli).
arxiv +1 more source
Fluorescent redox-dependent labeling of lipid droplets in cultured cells by reduced phenazine methosulfate [PDF]
Natural and synthetic phenazines are widely used in biomedical sciences. In dehydrogenase histochemistry, phenazine methosulfate (PMS) is applied as a redox reagent for coupling reduced coenzymes to the reduction of tetrazolium salts into colored formazans.
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Stress granule formation via ATP depletion-triggered phase separation [PDF]
Stress granules (SG) are droplets of proteins and RNA that form in the cell cytoplasm during stress conditions. We consider minimal models of stress granule formation based on the mechanism of phase separation regulated by ATP-driven chemical reactions. Motivated by experimental observations, we identify a minimal model of SG formation triggered by ATP
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Molecular motors transporting cargos in viscoelastic cytosol: how to beat subdiffusion with a power stroke? [PDF]
Anomalously slow passive diffusion, $\langle \delta x^2(t)\rangle\simeq t^{\alpha}$, with $0<\alpha<1$, of larger tracers such as messenger RNA and endogenous submicron granules in the cytoplasm of living biological cells has been demonstrated in a number of experiments and has been attributed to the viscoelastic physical nature of the cellular ...
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Biological measurement beyond the quantum limit [PDF]
Quantum noise places a fundamental limit on the per photon sensitivity attainable in optical measurements. This limit is of particular importance in biological measurements, where the optical power must be constrained to avoid damage to the specimen. By using non-classically correlated light, we demonstrated that the quantum limit can be surpassed in ...
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Evolution of exploding granules from coordinated observations by THEMIS, IRIS, SDO/HMI, and HINODE, and a simulation [PDF]
Exploding granules constitute the strongest horizontal flows on the quiet Sun and contribute to the structure of the surface horizontal velocity fields which build the large-scale organization of the discrete magnetic field. In this work we explore exploding granule expansion through the observations of the ground-based THEMIS telescope, IRIS, SDO, and
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Dynamics of small-scale convective motions [PDF]
Previous studies have discovered a population of small granules with diameters less than 800 km showing differing physical properties. High resolution simulations and observations of the solar granulation, in combination with automated segmentation and tracking algorithms, allow us to study the evolution of the structural and physical properties of ...
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WBCAtt: A White Blood Cell Dataset Annotated with Detailed Morphological Attributes [PDF]
The examination of blood samples at a microscopic level plays a fundamental role in clinical diagnostics, influencing a wide range of medical conditions. For instance, an in-depth study of White Blood Cells (WBCs), a crucial component of our blood, is essential for diagnosing blood-related diseases such as leukemia and anemia.
arxiv
Investigations of Sizes and Dynamical Motions of Solar Photospheric Granules by a Novel Granular Segmenting Algorithm [PDF]
Granules observed in solar photosphere are believed to be convective and turbulent, but the physical picture of granular dynamical process remains unclear. Here we performed an investigation of granular dynamical motions of full length scales based on data obtained by the 1-meter New Vacuum Solar Telescope (NVST) and the 1.6-meter Goode Solar Telescope
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Vector magnetic fields of Solar Granulation [PDF]
Observations of quiet Sun from the Solar Optical Telescope/Spectro-Polarimeter (SOT/SP) aboard the Hinode spacecraft would reveal the magnetic characters of the solar photosphere. By making use of the deep mode observations of three quiet regions, we have statistically studied the vector magnetic fields of solar granulation.
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