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Multiple Poliovirus Proteins Repress Cytoplasmic RNA Granules [PDF]

open access: yesViruses, 2015
We have previously shown that poliovirus (PV) infection induces stress granule (SG) formation early in infection and then inhibits the formation of SG and disperses processing bodies (PBs) by the mid-phase of infection.
Jonathan D. Dougherty   +2 more
doaj   +4 more sources

Sequestration of highly expressed mRNAs in cytoplasmic granules, P-bodies, and stress granules enhances cell viability. [PDF]

open access: goldPLoS Genetics, 2012
Transcriptome analyses indicate that a core 10%-15% of the yeast genome is modulated by a variety of different stresses. However, not all the induced genes undergo translation, and null mutants of many induced genes do not show elevated sensitivity to ...
Anna Lavut, Dina Raveh
doaj   +4 more sources

THE OCCURRENCE IN YEAST OF CYTOPLASMIC GRANULES WHICH RESEMBLE MICROBODIES [PDF]

open access: bronzeThe Journal of Cell Biology, 1968
Microbodies and microbody-like cytoplasmic granules have been identified by ultrastructural criteria in liver and kidney cells (1, 7, 17) and in various cell types in all major plant groups (14).
Charlotte J. Avers, Micheline Federman
semanticscholar   +5 more sources

Two Arabidopsis late pollen transcripts are detected in cytoplasmic granules. [PDF]

open access: yesPlant Direct, 2017
Many of mRNAs synthesized during pollen development are translated after germination, and we hypothesize that they are stored in cytoplasmic granules. We analyzed the cellular localization of the SKS14 and AT59 Arabidopsis mRNAs, which are orthologues of
Scarpin MR   +5 more
europepmc   +2 more sources

Single mRNP Analysis Reveals that Small Cytoplasmic mRNP Granules Represent mRNA Singletons [PDF]

open access: goldCell Reports, 2019
Summary: Small cytoplasmic mRNP granules are implicated in mRNA transport, translational control, and decay. Using super-resolution microscopy and fluorescence correlation spectroscopy, we analyzed the molecular composition and dynamics of single ...
Àngels Mateu-Regué   +5 more
doaj   +2 more sources

Cytolytic activity of purified cytoplasmic granules from cytotoxic rat large granular lymphocyte tumors. [PDF]

open access: bronzeJournal of Experimental Medicine, 1984
Purified cytoplasmic granules from cytotoxic rat large granular lymphocytes (LGL) tumors were cytolytic to erythrocytes, splenocytes, and a number of different lymphoid tumor cells.
Pierre A. Henkart   +3 more
openalex   +2 more sources

RNA-binding Motif Protein 4 Translocates to Cytoplasmic Granules and Suppresses Translation via Argonaute2 during Muscle Cell Differentiation [PDF]

open access: hybridJournal of Biological Chemistry, 2009
The RNA-binding motif protein 4 (RBM4) plays multiple roles in mRNA metabolism, including translation control. RBM4 suppresses cap-dependent translation but activates internal ribosome entry site-mediated translation. Because of its high expression level
Jung-Chun Lin, Woan‐Yuh Tarn
openalex   +2 more sources

Regulation of RNG105/caprin1 dynamics by pathogenic cytoplasmic FUS and TDP-43 in neuronal RNA granules modulates synaptic loss [PDF]

open access: goldHeliyon, 2023
In neurodegenerative diseases, the condensation of FUS and TDP-43 with RNA granules in neurons is linked to pathology, including synaptic disorders. However, the effects of FUS and TDP-43 on RNA granule factors remain unclear.
Tomoyo Horio   +3 more
doaj   +2 more sources

THE ISOLATION AND PROPERTIES OF THE SPECIFIC CYTOPLASMIC GRANULES OF RABBIT POLYMORPHONUCLEAR LEUCOCYTES [PDF]

open access: bronzeJournal of Experimental Medicine, 1960
A method has been described for isolation of the specific cytoplasmic granules of rabbit polymorphonuclear leucocytes. Homogeneous suspensions of leucocytes were disrupted by lysis in 0.34 M sucrose.
Zanvil A. Cohn, James G. Hirsch
openalex   +2 more sources

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