Results 141 to 150 of about 60,691 (243)

Elevated beta‐hydroxybutyrate within a pediatric population and its associated pathology: A retrospective case series

open access: yesJournal of Forensic Sciences, EarlyView.
Abstract Elevated beta‐hydroxybutyrate (BHB) is a marker for ketoacidosis. Post‐mortem values for the diagnosis of fatal ketoacidosis and the associated clinical and histologic findings are limited in the pediatric population. A retrospective case series of pediatric autopsy records and histology slides was conducted.
Nasim Haghandish   +3 more
wiley   +1 more source

TDRD3, a novel Tudor domain-containing protein, localizes to cytoplasmic stress granules [PDF]

open access: bronze, 2008
Isabelle Goulet   +4 more
openalex   +1 more source

ALS-linked cytoplasmic FUS assemblies are compositionally different from physiological stress granules and sequester hnRNPA3, a novel modifier of FUS toxicity

open access: gold, 2021
Haiyan An   +7 more
openalex   +1 more source

Climate Change, Air Quality, and Pollen Allergies—State of the Art and Recommendations for Research and Public Health

open access: yesAllergy, EarlyView.
ABSTRACT Allergies are one of the major health challenges of our time, associated with a high individual burden of disease and high costs for the healthcare system. Given their prevalence, allergies are also highly relevant from a public health perspective. The development of allergic diseases is multifactorial. In addition to individual factors (e.g.,
Jobst Augustin   +13 more
wiley   +1 more source

Targeting Immunologic Pathways in Eosinophilic Granulomatosis With Polyangiitis: Translating Emerging Evidence Into Clinical Practice

open access: yesAllergy, EarlyView.
ABSTRACT Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare and potentially life‐threatening systemic, inflammatory disease with multi‐organ manifestations, variable presentation and complex pathology. Multiple interconnected immunological pathways are implicated in EGPA pathology, including a type‐2 immune response driving predominantly ...
Harold Wilson‐Morkeh   +7 more
wiley   +1 more source

A model for de novo pigmentation of amelanotic retinal pigment epithelial cells

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose Retinal Pigment Epithelial (RPE) cells perform critical functions in the visual cycle. Their melanin pigmentation, which is organized into specialized compartments – melanosomes, is highly critical for proper vision. A chemical method to induce pigmentation in a non‐pigmented model of ARPE‐19 cells was applied using L‐DOPA as a ...
Santosh Gupta   +10 more
wiley   +1 more source

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