Results 11 to 20 of about 60,691 (243)

Compartmentalized oskar degradation in the germ plasm safeguards germline development

open access: yeseLife, 2020
Partitioning of mRNAs into ribonucleoprotein (RNP) granules supports diverse regulatory programs within the crowded cytoplasm. At least two types of RNP granules populate the germ plasm, a cytoplasmic domain at the posterior of the Drosophila oocyte and ...
Catherine E Eichler   +3 more
doaj   +1 more source

Highly Overexpressed AtC3H18 Impairs Microgametogenesis via Promoting the Continuous Assembly of mRNP Granules

open access: yesFrontiers in Plant Science, 2022
Plant CCCH zinc-finger proteins form a large family of regulatory proteins function in many aspects of plant growth, development and environmental responses.
Liai Xu   +7 more
doaj   +1 more source

Enrichment of Cytoplasmic RNA Granules from Arabidopsis Seedlings

open access: yesBio-Protocol, 2021
RNA granules (RGs) are membraneless intracellular compartments that play important roles in the post-transcriptional control of gene expression. Stress granules (SGs) are a type of RGs that form under environmental challenges and/or internal cellular ...
Zhen Lei, Eun Kim, Jungnam Cho
doaj   +1 more source

The TSN1 Binding Protein RH31 Is a Component of Stress Granules and Participates in Regulation of Salt-Stress Tolerance in Arabidopsis

open access: yesFrontiers in Plant Science, 2021
Tudor staphylococcal nucleases (TSNs) are evolutionarily conserved RNA binding proteins, which include redundant TSN1 and TSN2 in Arabidopsis. It has been showed TSNs are the components of stress granules (SGs) and regulate plant growth under salt stress.
Yanan Liu   +6 more
doaj   +1 more source

Principles of RNA recruitment to viral ribonucleoprotein condensates in a segmented dsRNA virus

open access: yeseLife, 2023
Rotaviruses transcribe 11 distinct RNAs that must be co-packaged prior to their replication to make an infectious virion. During infection, nontranslating rotavirus transcripts accumulate in cytoplasmic protein-RNA granules known as viroplasms that ...
Sebastian Strauss   +6 more
doaj   +1 more source

Zebrafish P54 RNA helicases are cytoplasmic granule residents that are required for development and stress resilience

open access: yesBiology Open, 2016
Stress granules are cytoplasmic foci that directly respond to the protein synthesis status of the cell. Various environmental insults, such as oxidative stress or extreme heat, block protein synthesis; consequently, mRNA will stall in translation, and ...
Cecilia Zampedri   +6 more
doaj   +1 more source

Single mRNP Analysis Reveals that Small Cytoplasmic mRNP Granules Represent mRNA Singletons

open access: yesCell Reports, 2019
Summary: Small cytoplasmic mRNP granules are implicated in mRNA transport, translational control, and decay. Using super-resolution microscopy and fluorescence correlation spectroscopy, we analyzed the molecular composition and dynamics of single ...
Àngels Mateu-Regué   +5 more
doaj   +1 more source

Mechanism and effect of stress granule formation in cancer and its potential roles in breast cancer therapy

open access: yesGenes and Diseases, 2022
Stress granules are non-membranous cytoplasmic foci induced by various stress conditions. It is a protective strategy used by cells to suppress overall translation during stress. In cancer cells, it was thought that the formation of stress granules could
Taobo Hu   +3 more
doaj   +1 more source

Phase transitioned nuclear Oskar promotes cell division of Drosophila primordial germ cells

open access: yeseLife, 2018
Germ granules are non-membranous ribonucleoprotein granules deemed the hubs for post-transcriptional gene regulation and functionally linked to germ cell fate across species.
Kathryn E Kistler   +7 more
doaj   +1 more source

An FNA pitfall: Mammary analog secretory carcinoma mistaken for acinic cell carcinoma due to cytoplasmic granules

open access: yesHuman Pathology: Case Reports, 2014
In the salivary gland, a key differential feature of Mammary analog secretory carcinoma (MASC) from acinic cell carcinoma (ACC) is the lack of cytoplasmic granules.
Nouf Hijazi, MD   +3 more
doaj   +1 more source

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