Results 91 to 100 of about 20,124 (297)

A unified model for Duchenne muscular dystrophy gene involvement in cancer: context‐dependent tumour suppression and oncogenicity

FEBS Open Bio, EarlyView.
We propose a context‐dependent model where the Duchenne muscular dystrophy (DMD) gene acts as a tumour suppressor in aggressive tumours and as an oncogene in less aggressive ones. We propose this model as a unified framework to explain the opposing survival associations with DMD expression and to guide experimental exploration of the dual role of DMD ...
Lee Machado, Leanne Jones, Sonika Divakar, Michael Naidoo, Karen Anthony   +4 more
wiley   +1 more source

Culex pipiens crossing type diversity is governed by an amplified and polymorphic operon of Wolbachia

Nature Communications, 2018
Wolbachia causes cytoplasmic incompatibility (CI) between mosquitoes infected with different strains, but the genetic basis of observed CI diversity is unknown. Here, Bonneau et al.
Manon Bonneau, Celestine Atyame, Marwa Beji, Fabienne Justy, Martin Cohen-Gonsaud, Mathieu Sicard, Mylène Weill   +6 more
doaj   +1 more source

Symbiosis As The Way Of Eukaryotic Life: The Dependent Co-Origination Of The Body [PDF]

, 2014
Molecular analyses of symbiotic relationships are challenging our biological definitions of individuality and supplanting them with a new notion of normal part whole relationships. This new notion is that of a \u27holobiont\u27, a consortium of organisms
Gilbert, Scott F.
core   +2 more sources

Functional Characterization and Pathogenicity Classification of PRRT2 Splice Variants in PRRT2‐Related Disorders

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Paroxysmal kinesigenic dyskinesia (PKD) is the most common hereditary paroxysmal movement disorder. The PRRT2 gene is the first identified causative gene and accounts for the majority of PKD. In this study, we investigated the pathogenicity of PRRT2 variants in the splice regions. Methods Patients with clinically suspected PKD and no
Jiao‐Jiao Xu, Yu‐Lan Chen, Wan‐Bing Sun, Hong‐Fu Li, Zhi‐Ying Wu, Dian‐Fu Chen   +5 more
wiley   +1 more source

Asymmetrical reinforcement and Wolbachia infection in Drosophila. [PDF]

PLoS Biology, 2006
Reinforcement refers to the evolution of increased mating discrimination against heterospecific individuals in zones of geographic overlap and can be considered a final stage in the speciation process. One the factors that may affect reinforcement is the
John Jaenike, Kelly A Dyer, Chad Cornish, Miranda S Minhas   +3 more
doaj   +1 more source

Over-expression of an S-domain receptor-like kinase extracellular domain improves panicle architecture and grain yield in rice. [PDF]

, 2015
The S-domain receptor kinase (SRK) comprises a highly polymorphic subfamily of receptor-like kinases (RLKs) originally found to be involved in the self-incompatibility response in Brassica.
Li, Hongyu, Lin, Chentao, Liu, Bin, Liu, Jun, Qin, Zhengrui, Zhang, Chengsheng, Zhang, Chunyu, Zhao, Tao, Zou, Xiaohua   +8 more
core   +2 more sources

Synthetic Strategy for mRNA Encapsulation and Gene Delivery with Nanoscale Metal‐Organic Frameworks

Advanced Functional Materials, EarlyView.
This research utilizes the ZIF‐8 for the encapsulation and intracellular delivery of nucleic acids, specifically mRNA, for applications in gene delivery. Integrating PEI addresses the issue of mRNA leakage from ZIF‐8, resulting in the delivery and expression of green fluorescent protein (GFP) in vitro and firefly luciferase in vivo.
Harrison Douglas Lawson, Huy Hoang Nguyen, Keng‐Jung Lee, Nattarat Wongsuwan, Ayesha Tupe, Mengrou Lu, Mariah Lynn Arral, Anne Behre, Zihan Ling, Kathryn Ann Whitehead, Adam Walter Feinberg, Xi Ren, Si‐Yang Zheng   +12 more
wiley   +1 more source

Horizontal transfer of parasitic sex ratio distorters between crustacean hosts [PDF]

, 1998
Parasitic sex ratio distorters were artificially transferred within and between crustacean host species in order to study the effects of parasitism on host fitness and sex determination and to investigate parasite–host specificity. Implantation of Nosema
Dunn, A.M., Rigaud, T.
core   +1 more source

Induced Paternal Effects Mimic Cytoplasmic Incompatibility in Drosophila [PDF]

Genetics, 2006
Abstract Wolbachia is an intracellular microbe found in a wide diversity of arthropod and filarial nematode hosts. In arthropods these common bacteria are reproductive parasites that manipulate central elements of their host's reproduction to increase their own maternal transmission in one of several ways. Cytoplasmic incompatibility (CI)
Timothy L. Karr, Michael E. Clark, Benjamin D. Heath, Cort L. Anderson, Cort L. Anderson   +4 more
openaire   +3 more sources

Fabrication of Free‐Standing Undulating Graphene Oxide Modular Tapered Pipes Using the Marangoni Effect

Advanced Functional Materials, EarlyView.
Free‐standing undulating graphene oxide (GO) modular tapered pipes fabricated based on the Marangoni effect and viscosity control are modular tubular structures that effectively utilize the lamination process between GO films. This novel tubular GO structure allows for the realization of various forms through the assembly of identical modules ...
Cheol‐Hwi Kim, Jeong Hyun Heo, Fu Nan Ju, Seo Young Kim, Chang‐Dae Kim, Hyungbin Son, Zhengtang Luo, Yoonhee Jin, Tae‐Hyung Kim   +8 more
wiley   +1 more source