Results 151 to 160 of about 17,887 (202)

Why Is Taurine Cytoprotective?

2003
The concept that taurine exhibits cytoprotective activity was introduced in 1981. Although several studies at the time had supported the notion that taurine was capable of modulating Ca2+movement, most of those studies focused on the transporter affected by taurine.
Stephen, Schaffer, Junichi, Azuma, Kyoko, Takahashi, Mahmood, Mozaffari   +3 more
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Cytoprotection: concepts and challenges

Supportive Care in Cancer, 1994
Clinical trials with several toxicity protectors (cytoprotective or chemoprotective agents) have been performed during the past decade. These trials are quite complex since they must include sufficient dose-limiting events for study, and assessment of both toxicity (and therefore the efficacy of protection) and antitumor effects must be carried out ...
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Cytoprotection and adapted cytoprotection

1985
Cytoprotection in the stomach can be defined as the phenomenon that damage to the gastric mucosa by irritating agents can be prevented. Data will be outlined below to show that two different forms of cytoprotection exist: 1. direct cytoprotection 2.
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Cytoprotection and intracellular calcium

Journal of Physiology-Paris, 1999
It seems that prostacyclin has an increasing effect on gastric mucosal (antral and fundic) calmodulin level in rats. Using either the calcium channel blocker verapamil or anti-calmodulin drugs (diazepam, trifluoperazine,) the cytoprotective effect of prostacyclin can be inhibited.
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Cytoprotection of the gastric epithelium

World Journal of Surgery, 1981
AbstractThe lining of the stomach of man is protected from its unique secretion, hydrochloric acid, by a variety of highly specialized characteristics. Foremost is its relative impermeability to hydrogen ions. The gastric surface epithelial cell which forms a continuous integument from the esophagus to the duodenum plays an important role in this ...
F G, Moody, C A, Zalewsky, K R, Larsen
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Overview of clinical cytoprotection

Digestive Diseases and Sciences, 1985
In thinking about cytoprotection five questions seem pertinent: (i) what is 'cytoprotection'? For convenience I shall use this term in spite of the semantic controversies between certain centers. (ii) How does cytoprotection occur? In other words what are the mechanisms that impart protection to the surface epithelial cells of the stomach and duodenum?
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Mechanisms of Gastric Cytoprotection

Journal of Clinical Gastroenterology, 1987
Gastric cytoprotection is a real but relative phenomenon that is induced by both endogenous and exogenous compounds. The key element in acute mucosal protection is the preservation of vascular integrity and the resulting maintenance of blood flow.
S, Szabo, G, Pihan
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Current history of cytoprotection

Prostaglandins, 1981
Abstract Several prostaglandins (PG) particularly those of the E type, inhibit gastric secretion in animals and humans. They also prevent ulcer formation and accelerate the rate of ulcer healing (gastric and duodenal, in animals and humans). The antiulcer activity was first ascribed to the antisecretory property.
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PROSTAGLANDINS, NSAIDs, AND CYTOPROTECTION

Gastroenterology Clinics of North America, 1992
Although the effects of prostaglandins on gastrointestinal secretion, blood flow, and motility are quite well characterized, the mechanism underlying the cytoprotective actions of this group of lipid mediators has yet to be clearly established. It seems likely that the ability of NSAIDs to inhibit gastric prostaglandin synthesis is an important ...
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Cytoprotective Channels in Mitochondria

Journal of Bioenergetics and Biomembranes, 2005
Several ion channels are expressed in the inner and outer membranes of mitochondria, but the exact function of these channels is not completely understood. The opening of certain channels is thought to induce the process of cell death or apoptosis. However, other channels of the inner mitochondrial membrane help protect against ischemic injury and ...
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