Results 131 to 140 of about 22,691 (239)

Endothelial TLR4 at the Crossroads of Vascular Senescence and Targeted Senotherapeutics

Aging Cell, Volume 25, Issue 10, October 2026.
While Toll‐like receptor 4 (TLR4) mediates essential innate immune responses, its stress‐induced hyperactivation drives vascular endothelial senescence. The subsequent release of the senescence‐associated secretory phenotype (SASP) accelerates tissue aging and exacerbates various age‐related diseases.
Hyo‐Jin Kim, Jeong‐Hyung Lee, Cheol Hwangbo   +2 more
wiley   +1 more source

Adaptive gastric mucosal cytoprotection in rats: different modes of action by three mild irritants

, 1996
The mechanisms of adaptive mucosal cytoprotection by mild irritants were investigated in rats. In an ex vivo chamber preparation, application of 20% ethanol, 5% NaCl or 0.3 M HCl to the posterior side of the mucosa significantly protected that side of ...
Ko, JKS, Cho, CH
core   +1 more source

Cytoprotection of human endothelial cells from menadione cytotoxicity by caffeic acid phenethyl ester: the role of heme oxygenase-1

, 2008
Caffeic acid phenethyl ester (CAPE), derived from various plant sources, has been shown to ameliorate ischemia/reperfusion injury in vivo, and this has been attributed to its ability to reduce oxidative stress.
Bowman, Phillip D., Zhaoa, Baiteng, Bynum, James A., Wang, Xinyu, Stavchansky, Salomon, Kerwin, Sean M.   +5 more
core   +1 more source

The role of macrophage migration inhibitory factor (MIF) in the pathogenesis and progression of cardiovascular disease

British Journal of Pharmacology, Volume 183, Issue 19, Page 5732-5751, October 2026.
Abstract Cardiovascular disease (CVD) remains the leading global cause of death, driven by complex mechanisms, in which chronic inflammation plays a central role. Inflammatory pathways contribute to all stages of CVD, from endothelial dysfunction and plaque formation to erosion, rupture and myocardial injury.
Shreya Mahabhashyam, James Harris, Jürgen Bernhagen, Antony Vinh, Katrina M. Mirabito Colafella   +4 more
wiley   +1 more source

SIRT1 in Neurodegenerative Diseases: Molecular Mechanisms, Disease Relevance, and Therapeutic Potential

The FASEB Journal, Volume 40, Issue 17, 15 September 2026.
SIRT1, an NAD+‐dependent deacetylase, supports cognitive resilience by coordinating neuroprotection, synaptic plasticity, autophagy–lysosomal proteostasis, and mitochondrial energy homeostasis. Reduced or dysregulated SIRT1 is associated with protein aggregation, neuroinflammation, mitochondrial dysfunction, synaptic loss, and cognitive decline in ...
Jiabin Duan, Jiaqi Liu, Qingsheng Meng, Jiahao Liu, Sitian Yang, Fang Zhou, Jing Cao   +6 more
wiley   +1 more source

Morphologic correlates of “cytoprotection”

Gastroenterology, 1983
P, Zeitoun, A, Duchateau
openaire   +2 more sources

Editorial: Brain cytoprotection for reperfusion injury after acute ischemic stroke. [PDF]

Front Neurol
Tang L, Zhao Z, Zhao W, Ikka L, Liu S, Wei M.   +5 more
europepmc   +1 more source

[Expression of Concern] Novel insights into the role of HSP90 in cytoprotection of H₂S against chemical hypoxia‑induced injury in H9c2  cardiac myocytes. [PDF]

Int J Mol Med
Yang Z, Yang C, Xiao L, Liao X, Lan A, Wang X, Guo R, Chen P, Hu C, Feng J.   +9 more
europepmc   +1 more source

Antiviral Activity of Essential Oil from <i>Populus balsamifera</i> L. Buds and Its Major Compounds Against Betacoronavirus HCoV-OC43 Using a Sensitive Cytoprotection Assay. [PDF]

Molecules
Girard L, Côté H, Pichette A, Savard J, Ripoll L, Legault J.   +5 more
europepmc   +1 more source

Cytoprotection Concepts for Ischemic Stroke in the Recanalization Era. [PDF]

Adv Sci (Weinh)
Boltze J, Fisher M.
europepmc   +1 more source