Results 121 to 130 of about 22,691 (239)

French Propolis Caffeic Acid Derivatives Protect Skeletal Muscle from Oxidative Damages

Biomolecules
Propolis produced by honeybees, Apis mellifera, has been valued since ancient times as a remedy for different ailments for its broad medicinal properties.
Luis Portillo-Lemus, Barbara Vernus, Béatrice Chabi, Aurélien Lebrun, Guillaume Cazals, Sylvie Rapior, Françoise Fons, Gilles Carnac, Sylvie Morel   +8 more
doaj   +1 more source

Trophoblast Extracellular Vesicles Rewire Immunity: A Symptom‐Relief Avenue for Recessive Dystrophic Epidermolysis Bullosa

Journal of Extracellular Vesicles, Volume 15, Issue 10, October 2026.
First‐trimester trophoblast EVs are enriched in anti‐inflammatory proteins, lipids, and immunoregulatory miRNAs. EVT‐EVs reprogram monocytes toward a pro‐resolving phenotype and restore immune homeostasis in RDEB, supporting their potential as offering a scalable off‐the‐shelf therapy for chronic inflammatory diseases.
Nell Hirt, Enzo Manchon, Ming Wu, Helene Le Buanec, Pauline Bataille, Emmanuelle Bourrat, Jean‐David Bouaziz, Nabila Jabrane‐Ferrat, Reem Al‐Daccak   +8 more
wiley   +1 more source

Maintaining Balance: An Update on Nonpharmacological Cytoprotection Therapy for Acute Ischemic Stroke

International audienceReperfusion therapies have become standard-of-care for patients with acute ischemic stroke (AIS). However, around half of treated patients do not regain functional independence despite successful recanalization.
Chen, Xi, Wu, Chuanjie, Zhang, Yang, Song, Baoying, Hu, Wenbo, Ji, Xunming, Zhou, Chen, Baron, Jean-Claude, Xu, Shuaili, Zhao, Wenbo, Wu, Di, Xu, Yi   +11 more
core   +1 more source

S-Methylmethionine (Vitamin U): A Critical Narrative Review of Pharmacological Mechanisms, Evidence Levels, and Translational Barriers

Pharmaceuticals
S-methylmethionine (SMM, also known as vitamin U) is a sulfur-containing vitamin-like compound that has been investigated since the 1940s for its gastroprotective and cytoprotective properties. Historically derived from observations of antiulcer activity
Arsen A. Ananian, Tatiana Z. Zelenina, Olga I. Stepanova, Anna A. Popova, Zurab T. Bagatelia, Svetlana I. Kosenkova, Grigory Yu. Evzikov, Boris B. Sysuev, Galina E. Brkich, Natalia V. Pyatigorskaya, Yuriy L. Vasil’ev, Elena O. Bakhrushina   +11 more
doaj   +1 more source

Multifunctional Hydrogels: Rational Design and Application in Regenerative Medicine

MedComm, Volume 7, Issue 10, October 2026.
Multifunctional hydrogels represent a paradigm shift in regenerative medicine, integrating rational material design with bioactive functionality to address complex tissue repair challenges. This review systematically examines the molecular engineering, structure–function relationships, and translational landscape of advanced hydrogel systems, spanning ...
Linyang Song, Epiphane K. Silli, Yazhen Xu, Huixia Lv, Ruoxian Song   +4 more
wiley   +1 more source

Effect of potassium chloride and actovegin infusions on cardiohemodynamics and enzymemia in acute period of myocardial infarction among patients with left ventricular systolic dysfunction

Российский кардиологический журнал, 2004
То investigate effect of potassium chloride and its combination with actovegin infusions on cardiohemodynamics and CK, AsAT, myoglobine levels in AMI associated with left ventricular systolic dysfunction, two groups of patients were examined ...
G. A. Bojarinov, O. V. Boennov, E. A. Baranov, N. Yu. Shevtzova, I. N. Shamelashvili   +4 more
doaj  

Design and synthesis of 1,4,8-triazaspiro[4.5]decan-2-one derivatives as novel mitochondrial permeability transition pore inhibitors

Journal of Enzyme Inhibition and Medicinal Chemistry
Ischaemia/reperfusion injury (IRI) is a condition that occurs when tissues from different organs undergo reperfusion following an ischaemic event.
Valentina Albanese, Gaia Pedriali, Martina Fabbri, Antonella Ciancetta, Silvia Ravagli, Chiara Roccatello, Remo Guerrini, Giampaolo Morciano, Delia Preti, Paolo Pinton, Salvatore Pacifico   +10 more
doaj   +1 more source

The Bile Acid Signaling Axis: Deciphering the Roles of FXR and TGR5 in Hepatic Steatosis, Fibrosis, and Cancer

Pharmacology Research &Perspectives, Volume 14, Issue 5, October 2026.
ABSTRACT Bile acids (BAs) serve not only as emulsifiers for lipid digestion but also as essential signaling molecules, governing various physiological and pathological processes through their interaction with the farnesoid X receptor (FXR) and the takeda G protein‐coupled receptor 5 (TGR5).
Jie Liu, Kui Sun, Hongmei Liu, Meiyang Zhu, Chunmeng Li, Yuqi He, Lin Qin   +6 more
wiley   +1 more source

Untargeted Metabolomic and Phytochemical Profiling of Berberis crataegina DC. Plant Parts: Antidiabetic Potential and Cytoprotection in High-Glucose-Exposed SH-SY5Y Cells

Pharmaceuticals
Background/Objectives: Berberis species are recognized for their ethnomedicinal importance and phytochemical richness associated with antidiabetic activity. Although B.
Yiğit Erkmen, Zekiye Ceren Arıtuluk Aydın, Engin Koçak, Hasya Nazlı Gök, Emirhan Nemutlu, Merve Yüzbaşıoğlu Baran   +5 more
doaj   +1 more source

Mechanistic Evaluation of Luteolin in Wound Healing of Diabetic Foot Ulcer via Nrf2 Signaling

Phytotherapy Research, Volume 40, Issue 10, Page 5901-5917, October 2026.
Proposed mechanism by which Luteolin (LU) promotes diabetic foot ulcer healing. LU attenuates hyperglycemia‐induced oxidative stress and lipid peroxidation, improves endothelial cell viability, and suppresses ferroptosis through Nrf2‐dependent antioxidant signaling, thereby accelerating angiogenesis and wound repair. ABSTRACT Diabetic foot ulcers (DFUs)
Muhammed Yusuf, Ayfer Busra Benkli, Ramiz Yusuf   +2 more
wiley   +1 more source