Results 121 to 130 of about 31,874 (246)

Prenylcysteine Oxidase 1 Deficiency Protects the Cardiac Muscle Cell Line HL‐1 Against Ischaemic/Hypoxic Stress

The FASEB Journal, Volume 40, Issue 8, 30 April 2026.
Ischaemic/hypoxic stress leads to heart remodeling and dysfunction. PCYOX1 promotes cardiomyocyte survival during injury, reducing the generation of reactive oxygen species. PCYOX1 deficiency regulates key proteins to preserve cardiomyocyte structure and function such as creatine kinase.
Cristina Banfi, Lisa Brocca, Alice Bascucci, Giulia Giusy Papaianni, Alice Mallia, Sonia Eligini   +5 more
wiley   +1 more source

The PPARβ/Delta‐Induced Mesenchymal Stromal Cell Secretome Has Cytoprotective Effects via ANGPTL4 in a Pre‐Clinical Model of Acute Lung Inflammation

The FASEB Journal, Volume 40, Issue 8, 30 April 2026.
Activation of PPARβδ via chemical agonists or free fatty acids lead to the increased production of ANGPTL4 by human bone marrow (BM)‐MSCs. MSC‐conditioned medium (CM) derived ANGPTL4 promotes wound healing in lung epithelial cells in vitro, enhances endothelial barrier function in vivo and reduced pro‐inflammatory cytokine release in a pre‐clinical ...
Courteney Tunstead, Molly Dunlop, Sinéad Ryan, Evelina Volkova, Evangeline Johnston, Sabrina Batah, Claudia C. Dos Santos, Bairbre McNicholas, Claire Masterson, John G. Laffey, Karen English   +10 more
wiley   +1 more source

Preventive cytoprotection in social diseases

Терапевтический архив, 2015
Among many cytoprotective drugs, only a few of them that have a targeted metabolic effect include agents that partially inhibit oxidation of free fatty acids, the so-called p-FOX inhibitors (partial fatty acid oxidation inhibitors). Aim.
A S Skotnikov, G N Gorokhovskaya, A M Shilov, V L Yun, M A Khamurzova   +4 more
doaj  

Therapeutic hypothermia with rapid thin liquid convection is safe and feasible in acute ischemic stroke patients: the SISCO pilot study

Frontiers in Neurology
BackgroundLaboratory studies have shown that rapid therapeutic hypothermia (TH) of <34 °C can reduce stroke infarct volume by over 50%. The EuroHyp-1 and ICTUS 2/3 trials found no benefits in the slow cooling of ischemic stroke patients, while ...
Justin A. Salerian, Robert B. Schock, Clemens M. Schirmer, Souvik Sen, Sheryl Martin-Schild, Oded Goren, Douglas F. Kupas, Robert J. Freedman, Aimee Aysenne   +8 more
doaj   +1 more source

Effects of pyruvate administration on infarct volume and neurological deficits following permanent focal cerebral ischemia in rats [PDF]

, 2003
Recent experimental evidences indicate that pyruvate, the final metabolite of glycolysis, has a remarkable protective effect against different types of brain injury.
Candelario-Jalil, Eduardo, Garcia-Cabrera, Michel, Gonzalez-Falcon, Armando, Leon, Olga S.   +3 more
core  

French Propolis Caffeic Acid Derivatives Protect Skeletal Muscle from Oxidative Damages

Biomolecules
Propolis produced by honeybees, Apis mellifera, has been valued since ancient times as a remedy for different ailments for its broad medicinal properties.
Luis Portillo-Lemus, Barbara Vernus, Béatrice Chabi, Aurélien Lebrun, Guillaume Cazals, Sylvie Rapior, Françoise Fons, Gilles Carnac, Sylvie Morel   +8 more
doaj   +1 more source

Locally targeted cytoprotection with dextran sulfate attenuates experimental porcine myocardial ischaemia/reperfusion injury [PDF]

, 2017
Aims Intravascular inflammatory events during ischaemia/reperfusion injury following coronary angioplasty alter and denudate the endothelium of its natural anticoagulant heparan sulfate proteoglycan (HSPG) layer, contributing to myocardial tissue damage.
Banz, Yara, Bovin, Nicolai V., Csizmadia, Eva, Haeberli, André, Hess, Otto M., Korchagina, Elena Y., Meier, Pascal, Mettler, Daniel, Rieben, Robert, Robson, Simon C.   +9 more
core  

Effect of potassium chloride and actovegin infusions on cardiohemodynamics and enzymemia in acute period of myocardial infarction among patients with left ventricular systolic dysfunction

Российский кардиологический журнал, 2004
То investigate effect of potassium chloride and its combination with actovegin infusions on cardiohemodynamics and CK, AsAT, myoglobine levels in AMI associated with left ventricular systolic dysfunction, two groups of patients were examined ...
G. A. Bojarinov, O. V. Boennov, E. A. Baranov, N. Yu. Shevtzova, I. N. Shamelashvili   +4 more
doaj  

Inhaled nitric oxide in premature infants: effect on tracheal aspirate and plasma nitric oxide metabolites. [PDF]

, 2010
ObjectiveInhaled nitric oxide (iNO) is a potential new therapy for prevention of bronchopulmonary dysplasia and brain injury in premature infants. This study examined dose-related effects of iNO on NO metabolites as evidence of NO delivery.Study designA ...
Ballard, PL, Ballard, RA, Cnaan, A, Golombek, SG, Gow, AJ, NO CLD Investigators, Posencheg, MA, Truog, WE   +7 more
core  

Intra‐Oral Lasering for the Treatment of Nasolabial Folds, Marionette Lines, and Jowls: Case Examples and Protocol Methodology

Journal of Cosmetic Dermatology, Volume 25, Issue 5, May 2026.
Richard J. Miron, Elsa McGilvray, Ana De Gomez Paz, Paras Ahmad   +3 more
wiley   +1 more source