Results 101 to 110 of about 22,691 (239)

Understanding extracellular vesicle biology, isolation, and characterization: The theory of EV‐erything

Periodontology 2000, EarlyView.
Abstract Background Extracellular vesicles (EVs), especially exosomes, are nanoparticles increasingly recognized as key regulators of intercellular communication in both physiological and pathological aspects. Despite rapid progress, inconsistencies in nomenclature, isolation, and characterization continue to restrict translational advancement.
Paras Ahmad, Nima Farshidfar, Nathan E. Estrin, Yulan Wang, Yufeng Zhang, Anton Sculean, Richard J. Miron   +6 more
wiley   +1 more source

NAD(P)H:quinone oxidoreductase 1 inducer activity of some novel anilinoquinazoline derivatives

Drug Design, Development and Therapy, 2016
Mostafa M Ghorab,1,2 Mansour S Alsaid,1 Maureen Higgins,3 Albena T Dinkova-Kostova,3–5 Abdelaaty A Shahat,1,6 Nehal H Elghazawy,7 Reem K Arafa7,8 1Department of Pharmacognosy, College of Pharmacy, King Saud University, Riyadh, Kingdom of Saudi ...
Ghorab MM, Alsaid MS, Higgins M, Dinkova-Kostova AT, Shahat AA, Elghazawy NH, Arafa RK   +6 more
doaj  

Mechanisms of haemoglobin mass expansion following heat stress

The Journal of Physiology, EarlyView.
Abstract figure legend Theorised mechanisms of heat stress‐induced erythropoiesis which may facilitate the expansion of haemoglobin mass. A, acute: heat stress‐induced renal ischaemia. Redistribution of blood flow away from the kidneys to facilitate thermoregulation during heat stress could reduce renal oxygen delivery, subsequently lowering renal PO2${
Elliott J. Jenkins, Brittany A. Edgett, Michael G. Hughes, Joshua C. Tremblay, Mike Stembridge   +4 more
wiley   +1 more source

Avian Eggshell Evolutionary Adaptations Inform Biomimetic Strategies for Next‑Generation Precision Cancer Theranostics

Advanced Oncology, Volume 1, Issue 1, December 2026.
ABSTRACT The avian eggshell is a sophisticated, multi‐functional biocomposite and, more importantly, an autonomous life‐support system evolved to safeguard embryonic development across dynamic and hostile environments. Discussing eggshell‐inspired biomaterials beyond simple structural imitation, this review translates these evolutionary survival ...
Zhiqiang Liu, Sida Ling, Mengqi Zhao, Chunyan Zhu, Yaoye Zhou, Hengquan Hou, Hui Zheng, Pengfei Yan, Peng Liu, Chang Yan, Zuyong Wang, Swee Hin Teoh   +11 more
wiley   +1 more source

A correlative study on the mechanism of adaptive cytoprotection against ethanol-induced gastric lesion formation in rats

, 1994
The protective effect of mild irritants against the subsequent gastric injury induced by necrotizing agents has been termed ‘adaptive cytoprotection'. In this study, the possible pathway and mechanisms of adaptive cytoprotection induced by 20% ethanol ...
Ko, JKS, Ogle, CW, Cho, CH
core   +1 more source

Targeting Oxidative and Immune Dysregulation in Wound Healing via Gold Nanoparticle Conjugate Chitosan

The FASEB Journal, Volume 40, Issue 19, 15 October 2026.
This gold nanoparticle–chitosan (AuNP@chitosan) composite promotes burn wound healing by simultaneously regulating endothelial and immune responses. In vitro, the composite protects TNF‐α‐injured HUVECs by reducing ROS, restoring thrombomodulin, and upregulating hypoxia‐adaptive markers.
Sheng‐Der Hsu, Shu‐Jen Chang, Cheng‐An Lin, Gang‐Yi Fan, Hsin‐Da Tsai, Amber Lin, Juin‐Hong Cherng   +6 more
wiley   +1 more source

Deconstruction of Human Age‐Related Cataract Capsules Defines Aging

Advanced Science, Volume 13, Issue 55, 5 October 2026.
We generate a comprehensive atlas of age‐related cataracts (ARC) at a single‐cell resolution, encompassing three disease states—mild cataract group (Mild), severe cortical cataract group (Severe_C), and severe nuclear cataract group (Severe_N). We find that ARC involves seven distinct lens capsule cell types, with notable differences in cellular ...
Qiaomei Tang, Ziyang Tong, Chunmei Fan, Silong Chen, Jiarui Guo, Jianghua Hu, Ke Yao, Zi Yin, Xiao Chen, Yibo Yu   +9 more
wiley   +1 more source

Implication of Mitochondrial Cytoprotection in Human Islet Isolation and Transplantation [PDF]

, 2020
Islet transplantation is a promising therapy for type 1 diabetes mellitus; however, success rates in achieving both short-and longterm insulin independence are not consistent, due in part to inconsistent islet quality and quantity caused by the complex ...
Tricia A Harvat, Hyojin Jeon, Joshua E Mendoza-Elias, Sang Joon Ahn, Dongyoung Lee, Yong Wang, José Oberholzer, Meirigeng Qi, Diana Gutierrez, Daniel Paushter   +9 more
core  

Hydrogen Sulfide Delivery to Enhance Bone Tissue Engineering Cell Survival

Pharmaceuticals
Though crucial for natural bone healing, local calcium ion (Ca2+) and phosphate ion (Pi) concentrations can exceed the cytotoxic limit leading to mitochondrial overload, oxidative stress, and cell death.
Soheila Ali Akbari Ghavimi, Trent J. Faulkner, Rama Rao Tata, August J. Hemmerla, Samantha E. Huddleston, Farnoushsadat Rezaei, Ethan S. Lungren, Rui Zhang, Erin E. Bumann, Bret D. Ulery   +9 more
doaj   +1 more source

Biophysical Characterization and Proteomic Analysis of Small Extracellular Vesicles Derived From Different Neural Cell Lines

Advanced NanoBiomed Research, Volume 6, Issue 10, October 2026.
This study systematically compares small extracellular vesicles (sEVs) derived from four neural cell lines, revealing how cellular origin shapes vesicle biophysical properties and proteomic cargo. Distinct, lineage‐specific signatures linked to neuronal, astrocytic, and microglial functions are identified, highlighting the importance of cell source ...
Muhammad Waqas Salim, Wei Zhang, Lyndsey E. Collins‐Praino, Andrew Care, Yuling Wang   +4 more
wiley   +1 more source