Results 91 to 100 of about 18,006 (203)

Metabolic Signatures of Aging and Gametogenesis in Hydra oligactis

Aging Cell, Volume 25, Issue 8, August 2026.
Hydra oligactis undergoes cold‐induced sexual differentiation and aging, culminating in death. GC–MS‐based metabolite profiling revealed signatures of gametogenesis, for example, polyamine accumulation, and of aging, such as loss of cytoprotection and neurotransmitter function, including taurine depletion.
Nicki Marami‐Zonouz, Erwann Arc, Thomas Roach, Pidder Jansen‐Dürr, Werner Bader, Bert Hobmayer, Ilse Kranner   +6 more
wiley   +1 more source

Integrated histopathological, physiological, biochemical, and molecular analysis of gill responses to acute salinity stress in red tilapia (Oreochromis spp.)

Journal of the World Aquaculture Society, Volume 57, Issue 4, August 2026.
Abstract Growing freshwater scarcity in China is driving aquaculture interests toward saline‐tolerant fish species. Red tilapia (Oreochromis spp.) is a euryhaline species with strong osmoregulatory capacity, making it an ideal model for investigating stress‐induced physiological changes.
Moustafa Saleh, Rahma Aboueleila, Mohamed Fekri Badran, Jixiang Hua, Yalun Dong, Siqi Lu, Wen‐jing Tao, Yifan Tao, Jun Qiang   +8 more
wiley   +1 more source

Preventive cytoprotection in social diseases

Терапевтический архив, 2015
Among many cytoprotective drugs, only a few of them that have a targeted metabolic effect include agents that partially inhibit oxidation of free fatty acids, the so-called p-FOX inhibitors (partial fatty acid oxidation inhibitors). Aim.
A S Skotnikov, G N Gorokhovskaya, A M Shilov, V L Yun, M A Khamurzova   +4 more
doaj  

Therapeutic hypothermia with rapid thin liquid convection is safe and feasible in acute ischemic stroke patients: the SISCO pilot study

Frontiers in Neurology
BackgroundLaboratory studies have shown that rapid therapeutic hypothermia (TH) of <34 °C can reduce stroke infarct volume by over 50%. The EuroHyp-1 and ICTUS 2/3 trials found no benefits in the slow cooling of ischemic stroke patients, while ...
Justin A. Salerian, Robert B. Schock, Clemens M. Schirmer, Souvik Sen, Sheryl Martin-Schild, Oded Goren, Douglas F. Kupas, Robert J. Freedman, Aimee Aysenne   +8 more
doaj   +1 more source

The Synthetic Melanocortin Agonist NDP‐MSH Ameliorates THSD7A‐Associated Membranous Nephropathy in an Active Immunization Mouse Model

The FASEB Journal, Volume 40, Issue 13, 15 July 2026.
Active immunization with recombinant THSD7A in mice induces autoreactive B cell activation and differentiation into CD138+ antibody‐secreting cells, leading to the production of anti‐THSD7A autoantibodies, glomerular immune injury and proteinuria, characteristic of membranous nephropathy. NDP‐MSH treatment modulates the MITF/IRF4 axis in primed B cells,
Mingzhuo Zhang, Mengxuan Chen, Yan Ge, William Gunning, Rujun Gong   +4 more
wiley   +1 more source

French Propolis Caffeic Acid Derivatives Protect Skeletal Muscle from Oxidative Damages

Biomolecules
Propolis produced by honeybees, Apis mellifera, has been valued since ancient times as a remedy for different ailments for its broad medicinal properties.
Luis Portillo-Lemus, Barbara Vernus, Béatrice Chabi, Aurélien Lebrun, Guillaume Cazals, Sylvie Rapior, Françoise Fons, Gilles Carnac, Sylvie Morel   +8 more
doaj   +1 more source

Effect of potassium chloride and actovegin infusions on cardiohemodynamics and enzymemia in acute period of myocardial infarction among patients with left ventricular systolic dysfunction

Российский кардиологический журнал, 2004
То investigate effect of potassium chloride and its combination with actovegin infusions on cardiohemodynamics and CK, AsAT, myoglobine levels in AMI associated with left ventricular systolic dysfunction, two groups of patients were examined ...
G. A. Bojarinov, O. V. Boennov, E. A. Baranov, N. Yu. Shevtzova, I. N. Shamelashvili   +4 more
doaj  

S-Methylmethionine (Vitamin U): A Critical Narrative Review of Pharmacological Mechanisms, Evidence Levels, and Translational Barriers

Pharmaceuticals
S-methylmethionine (SMM, also known as vitamin U) is a sulfur-containing vitamin-like compound that has been investigated since the 1940s for its gastroprotective and cytoprotective properties. Historically derived from observations of antiulcer activity
Arsen A. Ananian, Tatiana Z. Zelenina, Olga I. Stepanova, Anna A. Popova, Zurab T. Bagatelia, Svetlana I. Kosenkova, Grigory Yu. Evzikov, Boris B. Sysuev, Galina E. Brkich, Natalia V. Pyatigorskaya, Yuriy L. Vasil’ev, Elena O. Bakhrushina   +11 more
doaj   +1 more source

[Expression of Concern] Novel insights into the role of HSP90 in cytoprotection of H₂S against chemical hypoxia‑induced injury in H9c2  cardiac myocytes. [PDF]

Int J Mol Med
Yang Z, Yang C, Xiao L, Liao X, Lan A, Wang X, Guo R, Chen P, Hu C, Feng J.   +9 more
europepmc   +1 more source

Antiviral Activity of Essential Oil from <i>Populus balsamifera</i> L. Buds and Its Major Compounds Against Betacoronavirus HCoV-OC43 Using a Sensitive Cytoprotection Assay. [PDF]

Molecules
Girard L, Côté H, Pichette A, Savard J, Ripoll L, Legault J.   +5 more
europepmc   +1 more source