Results 91 to 100 of about 31,874 (246)
Photochemistry and Photobiology, Volume 101, Issue 2, Page 338-349, March/April 2025.In the present work with mouse models, we demonstrate that a novel compound, NEO400, is able to profoundly protect skin against damage caused by UV radiation (UVR) when it is applied to skin post‐UVR exposure. In comparison, Aloe vera or linoleic acid are unable to achieve a similar level of protection.
Stephen Swenson +6 more
wiley +1 more source
Reverse engineering of drug induced DNA damage response signalling pathway reveals dual outcomes of ATM kinase inhibition [PDF]
, 2013 The DNA Damage Response (DDR) pathway represents a signalling mechanism that is activated in eukaryotic cells following DNA damage and comprises of proteins involved in DNA damage detection, DNA repair, cell cycle arrest and apoptosis.
Bown, James L. +3 more
core +3 more sources
Mechanisms of haemoglobin mass expansion following heat stress
The Journal of Physiology, EarlyView.Abstract figure legend Theorised mechanisms of heat stress‐induced erythropoiesis which may facilitate the expansion of haemoglobin mass. A, acute: heat stress‐induced renal ischaemia. Redistribution of blood flow away from the kidneys to facilitate thermoregulation during heat stress could reduce renal oxygen delivery, subsequently lowering renal PO2${
Elliott J. Jenkins +4 more
wiley +1 more source
Induction of Cytoprotective Pathways Is Central to the Extension of Lifespan Conferred by Multiple Longevity Pathways [PDF]
, 2012 Many genetic and physiological treatments that extend lifespan also confer resistance to a variety of stressors, suggesting that cytoprotective mechanisms underpin the regulation of longevity.
A Ben-Zvi +100 more
core +4 more sources
The Journal of Physiology, EarlyView.Abstract figure legend Photobiomodulation restores blood–brain barrier (BBB) integrity following hypoxic stress. A multicellular human BBB model comprising brain microvascular endothelial cells, astrocytes and pericytes was established in a transwell system and subjected to acute hypoxia.
Mirriam Domocos +4 more
wiley +1 more source
Clinical Pharmacology &Therapeutics, Volume 119, Issue 6, Page 1494-1502, June 2026.Carfilzomib is highly effective in the treatment of multiple myeloma, but it has been associated with cardiovascular adverse events that impact patient outcomes. Our prior global metabolomic analyses indicated an association between hydrophilic bile acids and carfilzomib‐cardiotoxicity risk, although a causal relationship remained to be determined ...
Samia Shabnaz +15 more
wiley +1 more source
Nanoshell Fabrication Techniques for Probiotic Encapsulation: A Comprehensive Review
eFood, Volume 7, Issue 3, June 2026.ABSTRACT Probiotics, beneficial microorganisms, confer numerous health benefits when administered. However, their efficacy is hindered by harsh gut conditions, including acidity, bile acids, and enzymatic degradation. To overcome these challenges, encapsulation and nanoshell technology have emerged as a pivotal strategy to enhance probiotic stability ...
Tuba Mustafa +12 more
wiley +1 more source
Administration of Interleukin-15 Peptide Improves Cardiac Function in a Mouse Model of Myocardial Infarction. [PDF]
, 2020 Interleukin-15 is a pleotropic factor, capable of modulating metabolism, survival, proliferation, and differentiation in many different cell types.
Ameri, Kurosh +6 more
core
Redox Regulation and Oxidative Stress in Health and Disease: Mechanisms and Therapeutic Targeting
MedComm – Future Medicine, Volume 5, Issue 2, June 2026.Reactive species serve crucial roles which are tightly regulated in both physiological as well as disease states. At physiological levels, these species are integral to redox signaling, while uncontrolled redox promotes disease pathology. This review examines the dysregulation of these processes.
Mohammad Hossein Azadi +2 more
wiley +1 more source
Antioxidants, 2018 The Asteraceae family is economically very important, because many of these plants are grown mainly for their food value, such as lettuce (Lactuca), chicory (Cichorium), and sunflower (Heliantus aminus).
Wiem Meddeb +8 more
doaj +1 more source