Results 91 to 100 of about 17,887 (202)

Design and synthesis of 1,4,8-triazaspiro[4.5]decan-2-one derivatives as novel mitochondrial permeability transition pore inhibitors

Journal of Enzyme Inhibition and Medicinal Chemistry
Ischaemia/reperfusion injury (IRI) is a condition that occurs when tissues from different organs undergo reperfusion following an ischaemic event.
Valentina Albanese, Gaia Pedriali, Martina Fabbri, Antonella Ciancetta, Silvia Ravagli, Chiara Roccatello, Remo Guerrini, Giampaolo Morciano, Delia Preti, Paolo Pinton, Salvatore Pacifico   +10 more
doaj   +1 more source

Biomimetic Compartmentalization of Enzymes for Sustainable Coenzyme Recycling in Oxidative Photocatalysis

ChemBioChem, Volume 27, Issue 10, 27 May 2026.
This study presents a novel strategy inspired by the spatial compartmentalization of cellular metabolic pathways to address the challenge of coenzyme regeneration in enzyme–photocatalyst hybrid systems. Glucose dehydrogenase was encapsulated within silica nanoparticles, exploiting the short half‐life and limited diffusion distance of hydroxyl radicals ...
Myung Kyung Jung, So‐Hee Park, Dong‐Hyun You, Ji‐Soo Lee, Da‐Hye Ryu, Dae Youn Hwang, Beum‐Soo An, Seung Yun Yang, Sungbaek Seo, Youngwoo Choi, Seong‐Min Jo   +10 more
wiley   +1 more source

Preventive cytoprotection in social diseases

Терапевтический архив, 2015
Among many cytoprotective drugs, only a few of them that have a targeted metabolic effect include agents that partially inhibit oxidation of free fatty acids, the so-called p-FOX inhibitors (partial fatty acid oxidation inhibitors). Aim.
A S Skotnikov, G N Gorokhovskaya, A M Shilov, V L Yun, M A Khamurzova   +4 more
doaj  

Therapeutic hypothermia with rapid thin liquid convection is safe and feasible in acute ischemic stroke patients: the SISCO pilot study

Frontiers in Neurology
BackgroundLaboratory studies have shown that rapid therapeutic hypothermia (TH) of <34 °C can reduce stroke infarct volume by over 50%. The EuroHyp-1 and ICTUS 2/3 trials found no benefits in the slow cooling of ischemic stroke patients, while ...
Justin A. Salerian, Robert B. Schock, Clemens M. Schirmer, Souvik Sen, Sheryl Martin-Schild, Oded Goren, Douglas F. Kupas, Robert J. Freedman, Aimee Aysenne   +8 more
doaj   +1 more source

French Propolis Caffeic Acid Derivatives Protect Skeletal Muscle from Oxidative Damages

Biomolecules
Propolis produced by honeybees, Apis mellifera, has been valued since ancient times as a remedy for different ailments for its broad medicinal properties.
Luis Portillo-Lemus, Barbara Vernus, Béatrice Chabi, Aurélien Lebrun, Guillaume Cazals, Sylvie Rapior, Françoise Fons, Gilles Carnac, Sylvie Morel   +8 more
doaj   +1 more source

Effect of potassium chloride and actovegin infusions on cardiohemodynamics and enzymemia in acute period of myocardial infarction among patients with left ventricular systolic dysfunction

Российский кардиологический журнал, 2004
То investigate effect of potassium chloride and its combination with actovegin infusions on cardiohemodynamics and CK, AsAT, myoglobine levels in AMI associated with left ventricular systolic dysfunction, two groups of patients were examined ...
G. A. Bojarinov, O. V. Boennov, E. A. Baranov, N. Yu. Shevtzova, I. N. Shamelashvili   +4 more
doaj  

S-Methylmethionine (Vitamin U): A Critical Narrative Review of Pharmacological Mechanisms, Evidence Levels, and Translational Barriers

Pharmaceuticals
S-methylmethionine (SMM, also known as vitamin U) is a sulfur-containing vitamin-like compound that has been investigated since the 1940s for its gastroprotective and cytoprotective properties. Historically derived from observations of antiulcer activity
Arsen A. Ananian, Tatiana Z. Zelenina, Olga I. Stepanova, Anna A. Popova, Zurab T. Bagatelia, Svetlana I. Kosenkova, Grigory Yu. Evzikov, Boris B. Sysuev, Galina E. Brkich, Natalia V. Pyatigorskaya, Yuriy L. Vasil’ev, Elena O. Bakhrushina   +11 more
doaj   +1 more source

Morphologic correlates of “cytoprotection”

Gastroenterology, 1983
P, Zeitoun, A, Duchateau
openaire   +2 more sources

Publication Only

HemaSphere, Volume 10, Issue S1, June 2026.
wiley   +1 more source

[Expression of Concern] Novel insights into the role of HSP90 in cytoprotection of H₂S against chemical hypoxia‑induced injury in H9c2  cardiac myocytes. [PDF]

Int J Mol Med
Yang Z, Yang C, Xiao L, Liao X, Lan A, Wang X, Guo R, Chen P, Hu C, Feng J.   +9 more
europepmc   +1 more source